Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michaela K Back"'
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6298, p 6298 (2021)
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6298, p 6298 (2021)
Onset and progression of Alzheimer’s disease (AD) pathophysiology differs between brain regions. The neocortex, for example, is a brain region that is affected very early during AD. NMDA receptors (NMDARs) are involved in mediating amyloid beta (A
Autor:
David P. Wolfer, Lutz Slomianka, Susann Ludewig, Martin Korte, Kang Han, Dominique Fässler, Jakob von Engelhardt, Irmgard Amrein, Max Richter, Ulrike Müller, Michaela K Back, Susanne Erdinger, Vicky Steubler
Publikováno v:
The EMBO Journal, 40 (12)
e107471
The EMBO journal
England
The EMBO Journal
e107471
The EMBO journal
England
The EMBO Journal
The key role of APP for Alzheimer pathogenesis is well established. However, perinatal lethality of germline knockout mice lacking the entire APP family has so far precluded the analysis of its physiological functions for the developing and adult bra
Autor:
Dirk Grimm, Florian Hetsch, Janina Kupke, Anna D'Errico, Ralf H. Adams, Andromachi Karakatsani, Hellmut G. Augustin, Hyun-Woo Jeong, Géza Schermann, Michaela K Back, Heike Adler, Michele De Palma, Ellen Wiedtke, Robert Luck, Jakob von Engelhardt, Amparo Acker-Palmer, Carmen Ruiz de Almodovar, Nathalie Tisch, Bhavin Shah
Publikováno v:
Cell Reports
Neuro-vascular communication is essential to synchronize central nervous system development. Here, we identify angiopoietin/Tie2 as a neuro-vascular signaling axis involved in regulating dendritic morphogenesis of Purkinje cells (PCs). We show that i
Publikováno v:
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12664
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12664, p 12664 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12664, p 12664 (2021)
Mouse models are frequently used to study Huntington’s disease (HD). Onset and severity of neuronal and behavioral pathologies vary greatly between HD mouse models, which results from different huntingtin expression levels and different CAG repeat