Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Michaela Hull"'
1
Akademický článek
BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control
Autor: Christopher L Axelrod, William T King, Gangarao Davuluri, Robert C Noland, Jacob Hall, Michaela Hull, Wagner S Dantas, Elizabeth RM Zunica, Stephanie J Alexopoulos, Kyle L Hoehn, Ingeborg Langohr, Krisztian Stadler, Haylee Doyle, Eva Schmidt, Stephan Nieuwoudt, Kelly Fitzgerald, Kathryn Pergola, Hisashi Fujioka, Jacob T Mey, Ciaran Fealy, Anny Mulya, Robbie Beyl, Charles L Hoppel, John P Kirwan
Publikováno v: EMBO Molecular Medicine, Vol 12, Iss 7, Pp 1-20 (2020)
Abstract Obesity is a leading cause of preventable death worldwide. Despite this, current strategies for the treatment of obesity remain ineffective at achieving long‐term weight control. This is due, in part, to difficulties in identifying tolerab
Externí odkaz: https://doaj.org/article/61fe5cb6b2dd4631b169f643148abc19
Zobrazit plný text záznamu
2
Akademický článek
UCC118 supplementation reduces exercise‐induced gastrointestinal permeability and remodels the gut microbiome in healthy humans
Autor: Christopher L. Axelrod, Connery J. Brennan, Gail Cresci, Deborah Paul, Michaela Hull, Ciarán E. Fealy, John P. Kirwan
Publikováno v: Physiological Reports, Vol 7, Iss 22, Pp n/a-n/a (2019)
Abstract Dysregulation of gut microbiota and intestinal barrier function has emerged as potential mechanisms underlying digestive diseases, yet targeted therapies are lacking The purpose of this investigation was to assess the efficacy of UCC118, a c
Externí odkaz: https://doaj.org/article/104708f3fdad40feb3cee9c6cc0bcc5e
Zobrazit plný text záznamu
5
Facial Gunshot Wound: Mandibular Fracture With Internal Fixation and a Pectoralis Myocutaneous Flap Coverage
Autor: Michaela Hull, Kamran Shayesteh, William Aukerman, Siddhartha Nannapaneni
Publikováno v: Cureus
Facial penetrating gunshot wounds (GSWs) are seen in an assault, suicide, and accidental injury. They often carry high mortality given the important anatomical structures located within the neck. The foundations of maxillofacial GSWs are rooted in da
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ea81ecf0d2b5663544ee940034e569
http://europepmc.org/articles/PMC8087489
Zobrazit plný text záznamu
6
BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control
Autor: Jacob T. Mey, Gangarao Davuluri, Ciaran E. Fealy, Anny Mulya, Ingeborg M. Langohr, Elizabeth R M Zunica, Kathryn Pergola, Charles L. Hoppel, Christopher L. Axelrod, Kelly M. Fitzgerald, Krisztian Stadler, Michaela Hull, Hisashi Fujioka, Haylee Doyle, Stephanie J. Alexopoulos, Kyle L. Hoehn, Eva Schmidt, Robert C. Noland, Robbie A. Beyl, Stephan Nieuwoudt, Wagner S Dantas, Jacob Hall, John P. Kirwan, William T. King
Publikováno v: EMBO Molecular Medicine, Vol 12, Iss 7, Pp n/a-n/a (2020)
EMBO Molecular Medicine
Obesity is a leading cause of preventable death worldwide. Despite this, current strategies for the treatment of obesity remain ineffective at achieving long‐term weight control. This is due, in part, to difficulties in identifying tolerable and ef
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab58f8414c50e3db0b36ab79217b384
https://doaj.org/article/61fe5cb6b2dd4631b169f643148abc19
Zobrazit plný text záznamu
7
UCC118 supplementation reduces exercise-induced gastrointestinal permeability and remodels the gut microbiome in healthy humans
Autor: John P. Kirwan, Deborah Paul, Connery J. Brennan, Ciaran E. Fealy, Michaela Hull, Christopher L. Axelrod, Gail Cresci
Publikováno v: Physiological Reports
Physiological Reports, Vol 7, Iss 22, Pp n/a-n/a (2019)
Dysregulation of gut microbiota and intestinal barrier function has emerged as potential mechanisms underlying digestive diseases, yet targeted therapies are lacking The purpose of this investigation was to assess the efficacy of UCC118, a characteri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3378af3694d8d8fd1d69871687dc40
https://pubmed.ncbi.nlm.nih.gov/31758610
Zobrazit plný text záznamu
8
Pharmacologic Uncoupling of Skeletal Muscle Mitochondria Promotes Glucose Metabolism
Autor: Jessica Sacks, Michaela Hull, Kelly M. Fitzgerald, John P. Kirwan, Christopher L. Axelrod
Publikováno v: Diabetes. 67
Mitochondrial uncoupling was one of the earliest pharmacologic approaches to the treatment of obesity-related diseases. However, low mitochondrial specificity and negative off-target effects limited the viability of such agents. BAM15 is a small mole
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::812ebd380463d75c221625208941f025
https://doi.org/10.2337/db18-1778-p
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje