Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Michaela Hejl"'
Autor:
Juliana Ivanova, Rositsa Kukeva, Radostina Stoyanova, Tanya Zhivkova, Abedulkadir Abudalleh, Lora Dyakova, Radostina Alexandrova, Irena Pashkunova-Martic, Johannes Theiner, Peter Dorkov, Michaela Hejl, Michael A. Jakupec, Bernhard Keppler, Ivo Grabchev
Publikováno v:
Inorganics, Vol 12, Iss 8, p 206 (2024)
In this study we demonstrated for the first time synthetic procedures for composites of salinomycin (SalH) and two-line ferrihydrite. The products were characterized by various methods such as elemental analysis, attenuated total reflectance–Fourie
Externí odkaz:
https://doaj.org/article/e1f77c51436d46cb900135f3ca61b5ae
Autor:
Yvonne Lerchbammer-Kreith, Michaela Hejl, Dominik Wenisch, Michael A. Jakupec, Mathea S. Galanski, Bernhard K. Keppler
Publikováno v:
Inorganics, Vol 11, Iss 10, p 411 (2023)
A series of thirty novel tetracarboxylatoplatinum(IV) complexes in trans-configuration featuring combinations of mixed ammine, methylamine, dimethylamine, and cyclopentylamine ligands as well as acetato/propanoato and trifluoropropanoato ligands was
Externí odkaz:
https://doaj.org/article/6093e1aff91a4d12af737a1628b50509
Autor:
Yvonne Lerchbammer-Kreith, Michaela Hejl, Nadine S. Sommerfeld, Xian Weng-Jiang, Uchechukwu Odunze, Ryan D. Mellor, David G. Workman, Michael A. Jakupec, Andreas G. Schätzlein, Ijeoma F. Uchegbu, Mathea S. Galanski, Bernhard K. Keppler
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 1027 (2023)
Quaternary ammonium palmitoyl glycol chitosan (GCPQ) has already shown beneficial drug delivery properties and has been studied as a carrier for anticancer agents. Consequently, we synthesised cytotoxic platinum(IV) conjugates of cisplatin, carboplat
Externí odkaz:
https://doaj.org/article/b83c0dfc255c45309374a06652151faa
Autor:
Klaudia Cseh, Iker Berasaluce, Valentin Fuchs, Alexandra Banc, Andreas Schweikert, Alexander Prado-Roller, Michaela Hejl, Debora Wernitznig, Gunda Koellensperger, Michael A. Jakupec, Wolfgang Kandioller, Michael S. Malarek, Bernhard K. Keppler
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1875 (2023)
The synthesis, characterization and biological activity of tungstenocenes with varying biologically active (O,O–), (S,O–) and (N,O–) chelates are described. Complexes were characterized by 1H and 13C NMR, elemental analysis, ESI-mass spectromet
Externí odkaz:
https://doaj.org/article/ea3cf9f74c25426fa612f412705e4581
Autor:
Yvonne Lerchbammer-Kreith, Michaela Hejl, Petra Vician, Michael A. Jakupec, Walter Berger, Mathea S. Galanski, Bernhard K. Keppler
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1515 (2023)
Based on their drug delivery properties and activity against tumors, we combined PAMAM dendrimers with various platinum(IV) complexes in order to provide an improved approach of anticancer treatment. Platinum(IV) complexes were linked to terminal NH2
Externí odkaz:
https://doaj.org/article/a76602e5e3d84c4bb7a76ae7b269b879
Autor:
Klaudia Cseh, Heiko Geisler, Kristina Stanojkovska, Julia Westermayr, Philipp Brunmayr, Dominik Wenisch, Natalie Gajic, Michaela Hejl, Martin Schaier, Gunda Koellensperger, Michael A. Jakupec, Philipp Marquetand, Wolfgang Kandioller
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2466 (2022)
The main purpose of this study was to synthesize a new set of naphthoquinone-based ruthenium(II) arene complexes and to develop an understanding of their mode of action. This study systematically reviews the steps of synthesis, aiming to provide a si
Externí odkaz:
https://doaj.org/article/44bade57a6da472699725b6490e5fc1f
Autor:
Irena Pashkunova-Martic, Rositsa Kukeva, Radostina Stoyanova, Ivayla Pantcheva, Peter Dorkov, Joachim Friske, Michaela Hejl, Michael Jakupec, Mariam Hohagen, Anton Legin, Werner Lubitz, Bernhard K. Keppler, Thomas H. Helbich, Juliana Ivanova
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2319 (2022)
Combining therapeutic with diagnostic agents (theranostics) can revolutionize the course of malignant diseases. Chemotherapy, hyperthermia, or radiation are used together with diagnostic methods such as magnetic resonance imaging (MRI). In contrast t
Externí odkaz:
https://doaj.org/article/e50f045701ca45629fc7bdedbd6ad422
Autor:
Stephan Mokesch, Klaudia Cseh, Heiko Geisler, Michaela Hejl, Matthias H. M. Klose, Alexander Roller, Samuel M. Meier-Menches, Michael A. Jakupec, Wolfgang Kandioller, Bernhard K. Keppler
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
A series of 2-phenylbenzothiazole derivatives and their corresponding organometallic ruthenium(II) and osmium(II) complexes were synthesized, designed to exploit both, the attributes of the half-sandwich transition metal scaffold and the bioactivity
Externí odkaz:
https://doaj.org/article/68571d82c92d4b019aea10e20ae51176
Autor:
Stephan Mokesch, Daniela Schwarz, Michaela Hejl, Matthias H. M. Klose, Alexander Roller, Michael A. Jakupec, Wolfgang Kandioller, Bernhard K. Keppler
Publikováno v:
Molecules, Vol 24, Iss 13, p 2373 (2019)
Fine-tuning of the properties of a recently reported 1,3-indandione-based organoruthenium complex is attempted to optimize the stability under physiological conditions. Previous work has shown its capacity of inhibiting topoisomerase IIα; however, f
Externí odkaz:
https://doaj.org/article/dd3aa5952d9147769e35b1f58c7ae505
Autor:
Klaudia Cseh, Heiko Geisler, Natalie Gajic, Valentin Fuchs, Michael A. Jakupec, Michaela Hejl, Philipp Marquetand, Julia Westermayr, Wolfgang Kandioller, Sophia Harringer, Sarah Plutzar, Dominik Wenisch
Publikováno v:
Inorganic Chemistry
A series of nine RuII arene complexes bearing tridentate naphthoquinone-based N,O,O-ligands was synthesized and characterized. Aqueous stability and their hydrolysis mechanism were investigated via UV/vis photometry, HPLC-MS, and density functional t