Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michaela C. Olson"'
Autor:
Talia Greenstein, Bree B. Aldridge, Michaela C. Olson, Nhi Van, Jonah Larkins-Ford, Artem Sokolov, Yonatan N. Degefu
A lengthy multidrug chemotherapy is required to achieve a durable cure in tuberculosis. Variation in Mycobacterium tuberculosis drug response is created by the differing microenvironments in lesions, which generate different bacterial drug susceptibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be6ccfef80530830f5cd87514c55a38e
https://doi.org/10.1101/2021.02.03.429579
https://doi.org/10.1101/2021.02.03.429579
Autor:
Xin Wang, Joel S. Freundlich, Trever C. Smith, Michaela C. Olson, Jonah Larkins-Ford, Ian W. Richardson, Bree B. Aldridge, Sophia Hu, Krista M. Pullen, D. Michael Ando, Morgan E. McNellis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Tuberculosis is a leading cause of death in the world and requires treatment with an arduous multidrug regimen. Many new tuberculosis drugs are in development, and the drug development pipeline would benefit from more rapid methods to le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdfffc1a0bc673c28a52b3726270396
https://pubmed.ncbi.nlm.nih.gov/32680963
https://pubmed.ncbi.nlm.nih.gov/32680963
Autor:
Joel S. Freundlich, Michaela C. Olson, Jonah Larkins-Ford, Morgan E. McNellis, Krista M. Pullen, Bree B. Aldridge, D. Michael Ando, Sophia Hu, Ian W. Richardson, Trever C. Smith, Xin Wang
Morphological profiling is a method to classify target pathways of antibacterials based on how bacteria respond to treatment through changes to cellular shape and spatial organization. Here, we utilized the cell-to-cell variation in morphological fea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343e514275fa0b4ed623c2ab33ac639f
https://doi.org/10.1101/2020.03.11.987545
https://doi.org/10.1101/2020.03.11.987545
Autor:
Michaela C. Olson, Nhi Van, Jonah Larkins-Ford, Talia Greenstein, Bree B. Aldridge, Yonatan N. Degefu, Artem Sokolov
Publikováno v:
Cell Systems
Summary Lengthy multidrug chemotherapy is required to achieve a durable cure in tuberculosis. However, we lack well-validated, high-throughput in vitro models that predict animal outcomes. Here, we provide an extensible approach to rationally priorit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1fd5422e6b0088b198c36d31d1756f0
http://europepmc.org/articles/PMC8617591
http://europepmc.org/articles/PMC8617591