Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Michaela, Seeling"'
Autor:
Thomas Weissmann, Michael Rückert, Jian-Guo Zhou, Michaela Seeling, Sebastian Lettmaier, Anna-Jasmina Donaubauer, Falk Nimmerjahn, Oliver J. Ott, Markus Hecht, Florian Putz, Rainer Fietkau, Benjamin Frey, Udo S. Gaipl, Lisa Deloch
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Osteoarthritis (OA) is the leading degenerative joint disease in the western world and leads, if left untreated, to a progressive deterioration of joint functionality, ultimately reducing quality of life. Recent data has shown, that especially OA of
Externí odkaz:
https://doaj.org/article/7430f9a63ad5426197ea0ccd2a915717
Autor:
Clara-Sophie Kossel, Mandy Wahlbuhl, Sonia Schuepbach-Mallepell, Jung Park, Christine Kowalczyk-Quintas, Michaela Seeling, Klaus von der Mark, Pascal Schneider, Holm Schneider
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
X-linked hypohidrotic ectodermal dysplasia with the cardinal symptoms hypodontia, hypotrichosis and hypohidrosis is caused by a genetic deficiency of ectodysplasin A1 (EDA1). Prenatal EDA1 replacement can rescue the development of skin appendages and
Externí odkaz:
https://doaj.org/article/29f8c79279b345aaa0a27af1af43f8d9
Autor:
Olga O. Zaytseva, Michaela Seeling, Jasminka Krištić, Gordan Lauc, Marija Pezer, Falk Nimmerjahn
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Immunoglobulin G (IgG) is the most abundant immunoglobulin isotype in the blood and is involved in the pathogenesis and progression of various diseases. Glycosylation of the IgG fragment crystallizable (Fc) region is shown to vary in different physio
Externí odkaz:
https://doaj.org/article/0d5a34daaa8446c1acf26e65b1fdf2c7
Autor:
Lisa Deloch, Stephanie Hehlgans, Michael Rückert, Andreas Maier, Annika Hinrichs, Ann-Sophie Flohr, Denise Eckert, Thomas Weissmann, Michaela Seeling, Falk Nimmerjahn, Rainer Fietkau, Franz Rödel, Claudia Fournier, Benjamin Frey, Udo S. Gaipl
Publikováno v:
Cells, Vol 11, Iss 4, p 689 (2022)
Radon treatment is used as an established therapy option in chronic painful inflammatory diseases. While analgesic effects are well described, little is known about the underlying molecular effects. Among the suspected mechanisms are modulations of t
Externí odkaz:
https://doaj.org/article/58a965f20dc54cc5860cdf6ee44998fd
Autor:
Cecilia Engdahl, Albert Bondt, Ulrike Harre, Jasmin Raufer, René Pfeifle, Alessandro Camponeschi, Manfred Wuhrer, Michaela Seeling, Inga-Lill Mårtensson, Falk Nimmerjahn, Gerhard Krönke, Hans U. Scherer, Helena Forsblad-d’Elia, Georg Schett
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-11 (2018)
Abstract Background Rheumatoid arthritis (RA) preferentially affects women, with the peak incidence coinciding with estrogen decrease in menopause. Estrogen (E2) may therefore have intrinsic immune-regulatory properties that vanish with menopause. Fc
Externí odkaz:
https://doaj.org/article/e440625e94dc4c1c8ab28633f770c1aa
Autor:
Michaela Seeling, Matthias Pöhnl, Sibel Kara, Nathalie Horstmann, Carolina Riemer, Miriam Wöhner, Chunguang Liang, Christin Brückner, Patrick Eiring, Anja Werner, Markus Biburger, Leon Altmann, Martin Schneider, Lukas Amon, Christian H.K. Lehmann, Sooyeon Lee, Meik Kunz, Diana Dudziak, Georg Schett, Tobias Bäuerle, Anja Lux, Jan Tuckermann, Timo Vögtle, Bernhardt Nieswandt, Markus Sauer, Rainer A. Böckmann, Falk Nimmerjahn
Immunoglobulin G (IgG) antibodies are major drivers of inflammation during infectious and autoimmune diseases. In pooled serum IgG (IVIg), however, antibodies have a potent immunomodulatory and anti-inflammatory activity, but how this is mediated is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1351f723d8fef785ccb450d337d55549
https://publica.fraunhofer.de/handle/publica/441501
https://publica.fraunhofer.de/handle/publica/441501
Autor:
Anja Lux, Michaela Seeling, Anne Baerenwaldt, Birgit Lehmann, Inessa Schwab, Roland Repp, Norbert Meidenbauer, Andreas Mackensen, Arndt Hartmann, Gordon Heidkamp, Diana Dudziak, Falk Nimmerjahn
Publikováno v:
Cell Reports, Vol 7, Iss 1, Pp 236-248 (2014)
Genetic differences between humans and in vivo model systems, including mice and nonhuman primates, make it difficult to predict the efficacy of immunoglobulin G (IgG) activity in humans and understand the molecular and cellular mechanisms underlying
Externí odkaz:
https://doaj.org/article/36dfe42316c14b8aa11600d77db51bfd
Autor:
Thomas Winkler, Elena Percivalle, Dmytro Royzman, Falk Nimmerjahn, Vanessa Popp, Alexander Steinkasserer, Marina A Korn, Stefanie Brey, Elisabeth Zinser, Lars Nitschke, Michaela Seeling, Heike Schmitt, David Chambers, Sieglinde Angermüller, Uwe Thorsten Lux, Tobias Bäuerle, Christin Brückner
Publikováno v:
The Journal of Immunology. 205:2595-2605
Siglec-15 is a conserved sialic acid–binding Ig-like lectin, which is expressed on osteoclasts. Deficiency of Siglec-15 leads to an impaired osteoclast development, resulting in a mild osteopetrotic phenotype. The role of Siglec-15 in arthritis is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb1be2ed2379a526aa3eb3eedfc4590
https://doi.org/10.4049/jimmunol.2000472
https://doi.org/10.4049/jimmunol.2000472
Autor:
Olga O, Zaytseva, Michaela, Seeling, Jasminka, Krištić, Gordan, Lauc, Marija, Pezer, Falk, Nimmerjahn
Publikováno v:
Frontiers in Cell and Developmental Biology
Immunoglobulin G (IgG) is the most abundant immunoglobulin isotype in the blood and is involved in the pathogenesis and progression of various diseases. Glycosylation of the IgG fragment crystallizable (Fc) region is shown to vary in different physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25840d617c9b28545480b2df9388d267
https://pubmed.ncbi.nlm.nih.gov/32195245
https://pubmed.ncbi.nlm.nih.gov/32195245
Autor:
Joachim R. Göthert, Pegah Seddigh, Zeinab Abdullah, Franziska Neumann, Ari Waisman, Mike Hasenberg, Anika Klingberg, Sabrina Klebow, Michaela Seeling, Swen Engelmann, Sven Brandau, Annegret Reinhold, Anja Hasenberg, Linda Männ, Andreas Kraus, Manuel Stecher, Lars Borkenstein, Burkhart Schraven, Daniel R. Engel, Matthias Gunzer, Falk Nimmerjahn
Publikováno v:
Nature Methods. 12:445-452
Neutrophil granulocyte biology is a central issue of immunological research, but the lack of animal models that allow for neutrophil-selective genetic manipulation has delayed progress. By modulating the neutrophil-specific locus Ly6G with a knock-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ffb343dc029a602d3d765d797799a0
https://doi.org/10.1038/nmeth.3322
https://doi.org/10.1038/nmeth.3322