Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Michael. R. Holbrook"'
Autor:
Pramila Walpita, Yu Cong, Peter B. Jahrling, Oscar Rojas, Elena Postnikova, Shuiqing Yu, Lisa Johns, Michael. R. Holbrook
Publikováno v:
npj Vaccines, Vol 2, Iss 1, Pp 1-9 (2017)
Nipah virus: Virus-like particles protect against major public health concern A vaccine candidate consisting of virus-like particles could offer the first effective prophylaxis against the deadly Nipah virus. Endemic to Malaysia, Bangladesh, and Indi
Externí odkaz:
https://doaj.org/article/c73ddbefeb8a401ca3556c3aba293d75
Autor:
Thayne H. Dickey, Rui Ma, Sachy Orr-Gonzalez, Tarik Ouahes, Palak Patel, Holly McAleese, Brandi Butler, Elizabeth Eudy, Brett Eaton, Michael Murphy, Jennifer L. Kwan, Nichole D. Salinas, Michael R. Holbrook, Lynn E. Lambert, Niraj H. Tolia
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112266- (2023)
Summary: Waning immunity and emerging variants necessitate continued vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Improvements in vaccine safety, tolerability, and ease of manufacturing would benefit these efforts
Externí odkaz:
https://doaj.org/article/2f8a750ed97546e7a5f0d5c5d170d242
Autor:
Jana Sirmarova, Jiri Salat, Martin Palus, Vaclav Hönig, Helena Langhansova, Michael R. Holbrook, Daniel Ruzek
Publikováno v:
Emerging Microbes and Infections, Vol 7, Iss 1, Pp 1-12 (2018)
Abstract Kyasanur Forest disease virus (KFDV) is a highly pathogenic tick-borne flavivirus enzootic to India. In humans, KFDV causes a severe febrile disease. In some infected individuals, hemorrhagic manifestations, such as bleeding from the nose an
Externí odkaz:
https://doaj.org/article/c15ce01a93a14f51b137a8c249be8305
Autor:
Brian P Epling, Joseph M Rocco, Kristin L Boswell, Elizabeth Laidlaw, Frances Galindo, Anela Kellogg, Sanchita Das, Allison Roder, Elodie Ghedin, Allie Kreitman, Robin L Dewar, Sophie E M Kelly, Heather Kalish, Tauseef Rehman, Jeroen Highbarger, Adam Rupert, Gregory Kocher, Michael R Holbrook, Andrea Lisco, Maura Manion, Richard A Koup, Irini Sereti
Publikováno v:
Clinical Infectious Diseases. 76:573-581
Background Nirmatrelvir/ritonavir, the first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protease inhibitor, reduces the risk of hospitalization and death by coronavirus disease 2019 (COVID-19) but has been associated with symptomati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5048ffdbe16bdbdb0012f954d6ce766
https://doi.org/10.1093/cid/ciac663
https://doi.org/10.1093/cid/ciac663
Autor:
Cherrelle Dacon, Courtney Tucker, Linghang Peng, Chang-Chun D. Lee, Ting-Hui Lin, Meng Yuan, Yu Cong, Lingshu Wang, Lauren Purser, Jazmean K. Williams, Chul-Woo Pyo, Ivan Kosik, Zhe Hu, Ming Zhao, Divya Mohan, Andrew J. R. Cooper, Mary Peterson, Jeff Skinner, Saurabh Dixit, Erin Kollins, Louis Huzella, Donna Perry, Russell Byrum, Sanae Lembirik, David Drawbaugh, Brett Eaton, Yi Zhang, Eun Sung Yang, Man Chen, Kwanyee Leung, Rona S. Weinberg, Amarendra Pegu, Daniel E. Geraghty, Edgar Davidson, Iyadh Douagi, Susan Moir, Jonathan W. Yewdell, Connie Schmaljohn, Peter D. Crompton, Michael R. Holbrook, David Nemazee, John R. Mascola, Ian A. Wilson, Joshua Tan
Publikováno v:
Science. 377:728-735
The potential for future coronavirus outbreaks highlights the need to broadly target this group of pathogens. We used an epitope-agnostic approach to identify six monoclonal antibodies that bind to spike proteins from all seven human-infecting corona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00be51410add1f540a8cd59d08b048c3
https://doi.org/10.1126/science.abq3773
https://doi.org/10.1126/science.abq3773
Autor:
Mark N. Polizzotto, Jacqueline Nordwall, Abdel G. Babiker, Andrew Phillips, David M. Vock, Nnakelu Eriobu, Vivian Kwaghe, Roger Paredes, Lourdes Mateu, Srikanth Ramachandruni, Rajeev Narang, Mamta K. Jain, Susana M. Lazarte, Jason V. Baker, Anne E.P. Frosch, Garyfallia Poulakou, Konstantinos N. Syrigos, Gretchen S. Arnoczy, Natalie A. McBride, Philip A. Robinson, Farjad Sarafian, Sanjay Bhagani, Hassan S. Taha, Thomas Benfield, Sean T.H. Liu, Anastasia Antoniadou, Jens Ulrik Stæhr Jensen, Ioannis Kalomenidis, Adityo Susilo, Prasetyo Hariadi, Tomas O. Jensen MD, Jose Luis Morales-Rull, Marie Helleberg, Sreenath Meegada, Isik S. Johansen, Daniel Canario, Eduardo Fernández-Cruz, Simeon Metallidis, Amish Shah, Aki Sakurai, Nikolaos G. Koulouris, Robin Trotman, Amy C. Weintrob, Daria Podlekareva, Usman Hadi, Kathryn M. Lloyd, Birgit Thorup Røge, Sho Saito, Kelly Sweerus, Jakob J. Malin, Christoph Lübbert, Jose Muñoz, Matthew J. Cummings, Marcelo H. Losso, Dan Turner, Kathryn Shaw-Saliba, Robin Dewar, Helene Highbarger, Perrine Lallemand, Tauseef Rehman, Norman Gerry, Dona Arlinda, Christina C. Chang, Birgit Grund, Michael R. Holbrook, Horace P. Holley, Fleur Hudson, Laura A. McNay, Daniel D. Murray, Sarah L. Pett, Megan Shaughnessy, Mary C. Smolskis, Giota Touloumi, Mary E. Wright, Mittie K. Doyle, Sharon Popik, Christine Hall, Roshan Ramanathan, Huyen Cao, Elsa Mondou, Todd Willis, Joseph V. Thakuria, Leman Yel, Elizabeth Higgs, Virginia L. Kan, Jens D. Lundgren, James D. Neaton, H. Clifford Lane
Publikováno v:
Lancet (London, England)
Background Passive immunotherapy using hyperimmune intravenous immunoglobulin (hIVIG) to SARS-CoV-2, derived from recovered donors, is a potential rapidly available, specific therapy for an outbreak infection such as SARS-CoV-2. Findings from randomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fa915184eaa7554ec475c89515acde
https://doi.org/10.1016/s0140-6736(22)00101-5
https://doi.org/10.1016/s0140-6736(22)00101-5
Autor:
David X. Liu, Peter B. Jahrling, Russell Byrum, Danny Ragland, Donna L. Perry, Nejra Isic, Timothy K. Cooper, Louis Huzella, Rebecca J. Reeder, Kurt Cooper, Michael R. Holbrook, James Logue, Richard S. Bennett, Marisa St. Claire, Lisa E. Hensley, Randy Hart, Amanda M.W. Hischak
Publikováno v:
The American Journal of Pathology. 192:121-129
The pathogenesis of Ebola virus disease (EVD) is still incomplete, although the non-human primate model has been studied for more than 4 decades. To further investigate EVD pathogenesis, a natural history study has been conducted using 27 Chinese-ori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e3f4427c636123c80be2f8c9801d5fa
https://doi.org/10.1016/j.ajpath.2021.09.009
https://doi.org/10.1016/j.ajpath.2021.09.009
Autor:
Kenneth S Jensen, Ricky Adams, Richard S Bennett, John Bernbaum, Peter B Jahrling, Michael R Holbrook
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199534 (2018)
Nipah virus (NiV) is a highly pathogenic zoonotic paramyxovirus that can result in severe pulmonary disease and fatal encephalitis in humans and is responsible for outbreaks in Bangladesh, Malaysia, Singapore, India and possibly the Philippines. NiV
Externí odkaz:
https://doaj.org/article/b01127e22ba242cf840ac1956ee40c90
Autor:
Elena Postnikova, Yu Cong, Lisa Evans DeWald, Julie Dyall, Shuiqing Yu, Brit J Hart, Huanying Zhou, Robin Gross, James Logue, Yingyun Cai, Nicole Deiuliis, Julia Michelotti, Anna N Honko, Richard S Bennett, Michael R Holbrook, Gene G Olinger, Lisa E Hensley, Peter B Jahrling
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194880 (2018)
Identifying effective antivirals for treating Ebola virus disease (EVD) and minimizing transmission of such disease is critical. A variety of cell-based assays have been developed for evaluating compounds for activity against Ebola virus. However, ve
Externí odkaz:
https://doaj.org/article/b7073771bcb34e73930d7a2a00ff3b23
Autor:
Marcos J. Ramos-Benitez, Jeffrey R. Strich, Sara Alehashemi, Sydney Stein, Andre Rastegar, Adriana Almeida de Jesus, Farzana Bhuyan, Sabrina Ramelli, Ashley Babyak, Luis Perez-Valencia, Kevin M. Vannella, Gabrielle Grubbs, Surender Khurana, Robin Gross, Kyra Hadley, Janie Liang, Steven Mazur, Elena Postnikova, Seth Warner, Michael R. Holbrook, Lindsay M. Busch, Blake Warner, Willard Applefeld, Sarah Warner, Sameer S Kadri, Richard T Davey, Raphaela Goldbach-Mansky, Daniel S. Chertow
Publikováno v:
medRxiv : the preprint server for health sciences.
Understanding early innate immune responses to coronavirus disease 2019 (COVID–19) is crucial to developing targeted therapies to mitigate disease severity. Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection elicits interferon exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a81308166f3aaa47f6ef6de63ec448a
https://pubmed.ncbi.nlm.nih.gov/36415460
https://pubmed.ncbi.nlm.nih.gov/36415460