Zobrazeno 1 - 2
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pro vyhledávání: '"Michael eBlock"'
Publikováno v:
Frontiers in Physiology, Vol 4 (2013)
The renin-angiotensin-aldosterone system (RAAS) plays a key role in the pathogenesis of cardiovascular disorders including hypertension and is one of the most important targets for drugs. A whole body physiologically-based pharmacokinetic (wb PBPK) m
Externí odkaz:
https://doaj.org/article/ef0c720d57a64fd3a9a13d1240f59ebd
Autor:
Thomas eEissing, Lars eKuepfer, Corina eBecker, Michael eBlock, Katrin eCoboeken, Thomas eGaub, Linus eGoerlitz, Juergen eJaeger, Roland eLoosen, Bernd eLudewig, Michaela eMeyer, Christoph eNiederalt, Michael eSevestre, Hans-Ulrich eSiegmund, Juri eSolodenko, Kirstin eThelen, Ulrich eTelle, Wolfgang eWeiss, Thomas eWendl, Stefan eWillmann, Joerg eLippert
Publikováno v:
Frontiers in Physiology, Vol 2 (2011)
Today, in silico studies and trial simulations already complement experimental approaches in pharmaceutical R&D and have become indispensable tools for decision making and communication with regulatory agencies. While biology is multi-scale by nature
Externí odkaz:
https://doaj.org/article/0588ce89404e46678b3f03d96ab6ec8f