Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Michael Zuker"'
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 2, p e1001090 (2011)
MicroRNAs (miRNAs) suppress gene expression by forming a duplex with a target messenger RNA (mRNA), blocking translation or initiating cleavage. Computational approaches have proven valuable for predicting which mRNAs can be targeted by a given miRNA
Externí odkaz:
https://doaj.org/article/8654742d22b243c2b80127fcb7f473ad
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5745 (2009)
Transcriptional regulation by microRNAs (miRNAs) involves complementary base-pairing at target sites on mRNAs, yielding complex secondary structures. Here we introduce an efficient computational approach and software (FASTH) for genome-scale predicti
Externí odkaz:
https://doaj.org/article/a02d4d33919a464b82f25c6f74c0c49b
Publikováno v:
PLoS ONE, Vol 4, Iss 7 (2009)
Externí odkaz:
https://doaj.org/article/917c2f43dbac4ec4ab0eb4789686fdef
Autor:
Rachel Santiago, James E. Albrecht, Scott A. Tenenbaum, Pan T.X. Li, Michael Zuker, Papa Nii Asare-Okai, Sean Keller, William Stephenson
Publikováno v:
Phys. Chem. Chem. Phys.. 16:906-917
RNA folding in cells typically occurs at mesophilic temperatures. However, in vitro, RNA can be unfolded either by increasing temperature to values that are much higher than physiological, or by mechanically pulling structures apart at ambient temper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0ee447ded851f8035460df7c371598
https://doi.org/10.1039/c3cp52042k
https://doi.org/10.1039/c3cp52042k
Publikováno v:
RNA. 16:865-878
The use of free energy-based algorithms to compute RNA secondary structures produces, in general, large numbers of foldings. Recent research has addressed the problem of grouping structures into a small number of clusters and computing a representati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98beffcbe4cef9f66ade6bcd4fb1add
https://doi.org/10.1261/rna.903510
https://doi.org/10.1261/rna.903510
Autor:
Yanping P. Chen, Dawn Gundensen-Rindal, Jeff Pettis, Michael Zuker, Charles Murphy, Robin R. Gutell, Jay D. Evans
Publikováno v:
Journal of Eukaryotic Microbiology. 56:142-147
Nosema ceranae, a microsporidian parasite originally described from Apis cerana, has been found to infect Apis melllifera and is highly pathogenic to its new host. In the present study, data on the ultrastructure of N. ceranae, presence of N. ceranae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8998c8b131b903b4cde9de94ab7dce8
https://doi.org/10.1111/j.1550-7408.2008.00374.x
https://doi.org/10.1111/j.1550-7408.2008.00374.x
Autor:
Aadel A. Chaudhuri, Amy E. Pasquinelli, Robert Nissen, Clifford J. Tabin, Phillip A. Sharp, Michael T. McManus, Brian D. Harfe, Jennifer H. Mansfield, Raphael Farzan-Kashani, Jalagani Srineel, John C. Obenauer, Michael Zuker, Gary Ruvkun
Publikováno v:
Nature Genetics. 36:1079-1083
MicroRNAs (miRNAs) are a class of short ( approximately 22-nt) noncoding RNA molecules that downregulate expression of their mRNA targets. Since their discovery as regulators of developmental timing in Caenorhabditis elegans, hundreds of miRNAs have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893159184c441dc860a13d77eedf0f40
https://doi.org/10.1038/ng1421
https://doi.org/10.1038/ng1421
Autor:
Michael Zuker
Publikováno v:
Nucleic Acids Research. 31:3406-3415
The abbreviated name, 'mfold web server', describes a number of closely related software applications available on the World Wide Web (WWW) for the prediction of the secondary structure of single stranded nucleic acids. The objective of this web serv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b91db879c57a778a079826309b0781c
https://doi.org/10.1093/nar/gkg595
https://doi.org/10.1093/nar/gkg595
Autor:
Michael Zuker
Publikováno v:
Current Opinion in Structural Biology. 10:303-310
New results for calculating nucleic acid secondary structure by free energy minimization and phylogenetic comparisons have recently been reported. A complete set of DNA energy parameters is now available and the RNA parameters have been improved. Alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a25099d0473d12d9a7a938b9004ae3
https://doi.org/10.1016/s0959-440x(00)00088-9
https://doi.org/10.1016/s0959-440x(00)00088-9
Publikováno v:
Journal of Computational Biology. 7:277-292
Many different programs have been developed for the prediction of the secondary structure of an RNA sequence. Some of these programs generate an ensemble of structures, all of which have free energy close to that of the optimal structure, making it i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5022b25359afea8ab9dd2fd5f9a929d
https://doi.org/10.1089/10665270050081522
https://doi.org/10.1089/10665270050081522