Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michael Z. Palo"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Group I introns are catalytic RNAs that coordinate two consecutive transesterification reactions for self-splicing. To understand how the group I intron promotes catalysis and coordinates self-splicing reactions, we determine the structures
Externí odkaz:
https://doaj.org/article/018a293b8b7744bcba8619887a8752c2
Publikováno v:
Nucleic Acids Research. 51:1317-1325
Tetrahymena ribozyme is a group I intron, whose self-splicing is the result of two sequential ester-transfer reactions. To understand how it facilitates catalysis in the first self-splicing reaction, we used cryogenic electron microscopy (cryo-EM) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5b2ed24e29f207932bc65ed5aefad72
https://doi.org/10.1093/nar/gkac1268
https://doi.org/10.1093/nar/gkac1268
Autor:
Shanshan, Li, Michael Z, Palo, Grigore, Pintilie, Xiaojing, Zhang, Zhaoming, Su, Kalli, Kappel, Wah, Chiu, Kaiming, Zhang, Rhiju, Das
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(37)
The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63942d8fd7f3d2a81d0f8bce835fbbf0
https://pubmed.ncbi.nlm.nih.gov/36067294
https://pubmed.ncbi.nlm.nih.gov/36067294
Publikováno v:
Biochemistry
In all domains of life, multisubunit RNA polymerases (RNAPs) catalyze both the extension of mRNA transcripts by nucleotide addition and the hydrolysis of RNA, which enables proofreading by removal of misincorporated nucleotides. A highly conserved ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d5281f6f4c7ca79530f4f09234c066
https://pubmed.ncbi.nlm.nih.gov/34705427
https://pubmed.ncbi.nlm.nih.gov/34705427
Autor:
Ramya Rangan, Shanshan Li, Rhiju Das, Zhaoming Su, Kalli Kappel, Grigore D. Pintilie, Yuquan Wei, Bingnan Luo, Wah Chiu, Kaiming Zhang, Michael Z. Palo
Publikováno v:
Nature
Single-particle cryogenic electron microscopy (cryo-EM) has become a standard technique for determining protein structures at atomic resolution1–3. However, cryo-EM studies of protein-free RNA are in their early days. The Tetrahymena thermophila gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4476d4ea4c640ea124393872fcf65c52
https://pubmed.ncbi.nlm.nih.gov/34381213
https://pubmed.ncbi.nlm.nih.gov/34381213
Autor:
Juliane Merl-Pham, Tjasa Lepko, Tomohiro Yamazaki, Jernej Ule, Flora C.Y. Lee, Alexander Meissner, Stefanie M. Hauck, Gregor Rot, Michael Z. Palo, Boris Rogelj, Tetsuro Hirose, Micha Drukker, Ejona Rusha, Silvia Schirge, Miha Modic, Davide Cacchiarelli, Dmitry Shaposhnikov, Markus Grosch, Heiko Lickert, Christian von Mering
Publikováno v:
Molecular Cell
Summary RNA-binding proteins (RBPs) and long non-coding RNAs (lncRNAs) are key regulators of gene expression, but their joint functions in coordinating cell fate decisions are poorly understood. Here we show that the expression and activity of the RB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5bfd5db7bfe764de428436b7165c2f8
https://hdl.handle.net/21.11116/0000-0004-DA40-E21.11116/0000-0003-906C-1
https://hdl.handle.net/21.11116/0000-0004-DA40-E21.11116/0000-0003-906C-1
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f77deb491a5dc0c495c16beb6f24da5
https://doi.org/10.1096/fasebj.2019.33.1_supplement.624.2
https://doi.org/10.1096/fasebj.2019.33.1_supplement.624.2
Publikováno v:
Proceedings of the National Academy of Sciences. 114
The active site of multisubunit RNA polymerases (RNAPs) is highly conserved from humans to bacteria. This single site catalyzes both nucleotide addition required for RNA transcript synthesis and excision of incorrect nucleotides after misincorporatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feece103d1006f803c0d1f237c490d8d
https://doi.org/10.1073/pnas.1702383114
https://doi.org/10.1073/pnas.1702383114