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pro vyhledávání: '"Michael Y.-X. Ma"'
Autor:
Shaji T. George, Biji Jacob-Samuel, Jeanne C. Dignam, Steven H. Gray, Godwin W. Fong, Michael Y.-X. Ma, Linhui Li
Publikováno v:
Nucleic Acids Research. 25:3590-3593
3-ethoxy-1,2,4-dithiazoline-5-one (EDITH) was recently introduced as an efficient sulfurizing reagent for solid-phase oligonucleotide synthesis. The successful syntheses were performed using standard base protecting groups (i.e. benzoyl for A and C,
Autor:
Raya Kuperman, Shane C. Climie, Wing C. Lin, Richard W. Barnett, Kirk McCallum, Michael Y.-X. Ma, Martin Sumner-Smith
Publikováno v:
Nucleic acids research. 21(11)
We recently developed an approach which allows rapid generation of short, double-stranded oligonucleotides whereby one end of the duplex was joined and stabilized by a synthetic linker of specific design (miniduplexes)(6). Model miniduplexes based on
Autor:
Shane C. Climie, Wing C. Lin, Raya Kuperman, Richard W. Barnett, Martin Sumner-Smith, Lorne S. Reid, Michael Y.-X. Ma
Publikováno v:
Biochemistry. 32(7)
Double-stranded oligodeoxyribonucleotides or single-stranded oligoribonucleotides with specific secondary structure have been proposed as potential antagonists to target nucleic acid-binding proteins (the sense approach). A major limitation of this s