Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Michael Y. Zhao"'
1
Akademický článek
Convenient decagram scale preparation of ethyl 3,4-diethylpyrrole-2-carboxylate, a versatile precursor for pyrrole-based macrocycles and chromophores
Autor: Axel Steinbrueck, James T. Brewster, II, Michael Y. Zhao, Adam C. Sedgwick, Jonathan L. Sessler
Publikováno v: Results in Chemistry, Vol 2, Iss , Pp 100075- (2020)
Herein, we describe a detailed preparation of the versatile pyrrole building block 3,4-diethylpyrrole-2-carboxylate (1), a key structural feature in various porphyrins, porphyrinoids, and other chromophores. 1 was prepared via a one-pot DBU catalyzed
Externí odkaz: https://doaj.org/article/ca12254ef6074873949bb4cd2a51a823
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2
Akademický článek
A Deferasirox Derivative That Acts as a Multifaceted Platform for the Detection and Quantification of Fe3+
Autor: Axel Steinbrueck, Adam C. Sedgwick, Suh-Mi Hwang, Sajal Sen, Michael Y. Zhao, Dan-Ying Huang, Daniel M. Knoll, Yu-Ying Wang, Jonathan L. Sessler
Publikováno v: Chemosensors, Vol 9, Iss 4, p 68 (2021)
Here, we report that ExSO3H, a synthetically accessible, water-soluble, non-toxic derivative of the clinical iron chelator deferasirox, acts as a colorimetric chemosensor that permits the detection and quantification of Fe3+ in aqueous samples at pH
Externí odkaz: https://doaj.org/article/70c03152a38e43829d4ea61007b259b5
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3
Akademický článek
Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection
Autor: Xia Liu, Jingjing Yu, Longyong Xu, Katharine Umphred-Wilson, Fanglue Peng, Yao Ding, Brendan M Barton, Xiangdong Lv, Michael Y Zhao, Shengyi Sun, Yuning Hong, Ling Qi, Stanley Adoro, Xi Chen
Publikováno v: eLife, Vol 10 (2021)
Signals from the pre-T cell receptor and Notch coordinately instruct β-selection of CD4–CD8–double negative (DN) thymocytes to generate αβ T cells in the thymus. However, how these signals ensure a high-fidelity proteome and safeguard the clon
Externí odkaz: https://doaj.org/article/a0882b95451b420da0b3daebf835253f
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6
In vitro studies of deferasirox derivatives as potential organelle-targeting traceable anti-cancer therapeutics
Autor: Dan-Ying Huang, Hai-Hao Han, Axel Steinbrueck, Xiao-Peng He, Adam C. Sedgwick, Michael Y. Zhao, Sajal Sen, Jia Li, Yi Zang, Jonathan L. Sessler
Publikováno v: Chem Commun (Camb)
We report here strategic functionalization of the FDA approved chelator deferasirox (1) in an effort to produce organelle-targeting iron chelators with enhanced activity against A549 lung cancer cells. Derivative 8 was found to have improved antiprol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df7c9b600b88aab7080d3090deb97cf
https://doi.org/10.1039/d0cc08156f
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7
Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection
Autor: Fanglue Peng, Shengyi Sun, Ling Qi, Brendan M Barton, Michael Y Zhao, Xiangdong Lv, Yao Ding, Yuning Hong, Katharine Umphred-Wilson, Xia Liu, Stanley Adoro, Longyong Xu, Xi Chen, Jingjing Yu
Publikováno v: eLife
eLife, Vol 10 (2021)
Signals from the pre-T cell receptor and Notch coordinately instruct β-selection of CD4–CD8–double negative (DN) thymocytes to generate αβ T cells in the thymus. However, how these signals ensure a high-fidelity proteome and safeguard the clon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2e91d1f7bf2695bbc5208a8cd33e67
http://europepmc.org/articles/PMC8315795
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9
Notch-Induced Endoplasmic Reticulum-Associated Degradation Governs Thymocyte β−Selection
Autor: Jingjing Yu, Stanley Adoro, Yao Ding, Xiangdong Lv, Xia Liu, Fanglue Peng, Longyong Xu, Yuning Hong, Xi Chen, Brendan M Barton, Shengyi Sun, Katharine Umphred-Wilson, Ling Qi, Michael Y Zhao
Signals from the pre-T cell receptor and Notch coordinately instruct β-selection of CD4−CD8− double negative (DN) thymocytes to generate αβ T cells in the thymus. However, how these signals ensure a high-fidelity proteome and safeguard the clo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8355c21411cd1ee3f308f6e98bc5b79
https://doi.org/10.1101/2021.05.06.443041
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10
A Deferasirox Derivative That Acts as a Multifaceted Platform for the Detection and Quantification of Fe3+
Autor: Yu-Ying Wang, Michael Y. Zhao, Adam C. Sedgwick, Axel Steinbrueck, Suh-Mi Hwang, Dan-Ying Huang, Jonathan L. Sessler, Sajal Sen, Daniel M. Knoll
Publikováno v: Chemosensors
Volume 9
Issue 4
Chemosensors, Vol 9, Iss 68, p 68 (2021)
Here, we report that ExSO3H, a synthetically accessible, water-soluble, non-toxic derivative of the clinical iron chelator deferasirox, acts as a colorimetric chemosensor that permits the detection and quantification of Fe3+ in aqueous samples at pH
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20bcaa88d3c8adb3a2acbf72420aee0f
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