Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Michael Y Zhang"'
Autor:
Sabine Topka, Joseph Vijai, Michael F Walsh, Lauren Jacobs, Ann Maria, Danylo Villano, Pragna Gaddam, Gang Wu, Rose B McGee, Emily Quinn, Hiroto Inaba, Christine Hartford, Ching-Hon Pui, Alberto Pappo, Michael Edmonson, Michael Y Zhang, Polina Stepensky, Peter Steinherz, Kasmintan Schrader, Anne Lincoln, James Bussel, Steve M Lipkin, Yehuda Goldgur, Mira Harit, Zsofia K Stadler, Charles Mullighan, Michael Weintraub, Akiko Shimamura, Jinghui Zhang, James R Downing, Kim E Nichols, Kenneth Offit
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005262 (2015)
Somatic mutations affecting ETV6 often occur in acute lymphoblastic leukemia (ALL), the most common childhood malignancy. The genetic factors that predispose to ALL remain poorly understood. Here we identify a novel germline ETV6 p. L349P mutation in
Externí odkaz:
https://doaj.org/article/857b67bb97a141dd80ae77fd0dd250d4
Autor:
Takahide Nejo, Lin Wang, Kevin K. Leung, Albert Wang, Senthilnath Lakshmanachetty, Marco Gallus, Darwin W. Kwok, Chibo Hong, Lee H. Chen, Diego A. Carrera, Michael Y. Zhang, Nicholas O. Stevers, Gabriella C. Maldonado, Akane Yamamichi, Payal B. Watchmaker, Akul Naik, Anny Shai, Joanna J. Phillips, Susan M. Chang, Arun P. Wiita, James A. Wells, Joseph F. Costello, Aaron A. Diaz, Hideho Okada
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Despite advancements in cancer immunotherapy, solid tumors remain formidable challenges. In glioma, profound inter- and intra-tumoral heterogeneity of antigen landscape hampers therapeutic development. Therefore, it is critical to consider a
Externí odkaz:
https://doaj.org/article/4c9ca26f096d46feb278b4dfc8e66f04
Autor:
Micaela G. Fosdick, Pratik Rajesh Chheda, Phuong M. Tran, Alex Wolff, Ronal Peralta, Michael Y. Zhang, Robert Kerns, Jon C. D. Houtman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Glycerol monolaurate (GML), a naturally occurring monoglyceride, is widely used commercially for its antimicrobial properties. Interestingly, several studies have shown that GML not only has antimicrobial properties but is also an anti-infla
Externí odkaz:
https://doaj.org/article/3f0a0641182b469a9ee320d86e8250d8
Autor:
Abrar Choudhury, Stephen T. Magill, Charlotte D. Eaton, Briana C. Prager, William C. Chen, Martha A. Cady, Kyounghee Seo, Calixto-Hope G. Lucas, Tim J. Casey-Clyde, Harish N. Vasudevan, S. John Liu, Javier E. Villanueva-Meyer, Tai-Chung Lam, Jenny Kan-Suen Pu, Lai-Fung Li, Gilberto Ka-Kit Leung, Danielle L. Swaney, Michael Y. Zhang, Jason W. Chan, Zhixin Qiu, Michael V. Martin, Matthew S. Susko, Steve E. Braunstein, Nancy Ann Oberheim Bush, Jessica D. Schulte, Nicholas Butowski, Penny K. Sneed, Mitchel S. Berger, Nevan J. Krogan, Arie Perry, Joanna J. Phillips, David A. Solomon, Joseph F. Costello, Michael W. McDermott, Jeremy N. Rich, David R. Raleigh
Publikováno v:
Nature genetics, vol 54, iss 5
Nat Genet
Nat Genet
Meningiomas are the most common primary intracranial tumors. There are no effective medical therapies for meningioma patients, and new treatments have been encumbered by limited understanding of meningioma biology. Here, we use DNA methylation profil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fe497895b27e3b5342d54b19fe322d
https://doi.org/10.1038/s41588-022-01061-8
https://doi.org/10.1038/s41588-022-01061-8
Autor:
Roman O. Kowalchuk, Ajay Niranjan, Judith Hess, Joseph P. Antonios, Michael Y. Zhang, Steve Braunstein, Richard B. Ross, Stylianos Pikis, Christopher P. Deibert, Cheng-chia Lee, Huai-che Yang, Anne-Marie Langlois, David Mathieu, Selcuk Peker, Yavuz Samanci, Chad G. Rusthoven, Veronica Chiang, Zhishuo Wei, L. Dade Lunsford, Daniel M. Trifiletti, Jason P. Sheehan
Publikováno v:
Journal of neurosurgery.
OBJECTIVE Stereotactic radiosurgery (SRS) is an effective treatment for intracranial metastatic disease, but its role in triple-negative breast cancer requires further study. Herein, the authors report overall survival (OS) and local tumor control in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7479024130a880ef3bf555b272b2e5a9
https://pubmed.ncbi.nlm.nih.gov/36433878
https://pubmed.ncbi.nlm.nih.gov/36433878
Autor:
Michael Y. Zhang, Siobán B. Keel, Tom Walsh, Ming K. Lee, Suleyman Gulsuner, Amanda C. Watts, Colin C. Pritchard, Stephen J. Salipante, Michael R. Jeng, Inga Hofmann, David A. Williams, Mark D. Fleming, Janis L. Abkowitz, Mary-Claire King, Akiko Shimamura
Publikováno v:
Haematologica, Vol 100, Iss 1 (2015)
Accurate and timely diagnosis of inherited bone marrow failure and inherited myelodysplastic syndromes is essential to guide clinical management. Distinguishing inherited from acquired bone marrow failure/myelodysplastic syndrome poses a significant
Externí odkaz:
https://doaj.org/article/99cc2267d23347f9a4d88322df9476dd
Autor:
Michael Y. Zhang, Micaela G. Fosdick, Pratik Rajesh Chheda, Jon C. D. Houtman, Alex Wolff, Phuong M. Tran, Ronal Peralta, Robert J. Kerns
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Glycerol monolaurate (GML), a naturally occurring monoglyceride, is widely used commercially for its antimicrobial properties. Interestingly, several studies have shown that GML not only has antimicrobial properties but is also an anti-inflammatory a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe6c23a749731d1c9a16316fa88bd00
https://doi.org/10.1038/s41598-021-88584-y
https://doi.org/10.1038/s41598-021-88584-y
Autor:
Abrar Choudhury, Stephen T. Magill, Charlotte D. Eaton, Briana C. Prager, William C. Chen, Kyounghee Seo, Calixto-Hope G. Lucas, Javier E. Villanueva-Meyer, Tai-Chung Lam, Jenny Kan-Suen Pu, Lai-Fung Li, Gilberto Ka-Kit Leung, Harish N. Vasudevan, S. John Liu, Jason W. Chan, Zhixin Qiu, Michael Y. Zhang, Michael V. Martin, Matthew S. Susko, Steve E. Braunstein, Nancy Ann Oberheim Bush, Jessica Schulte, Nicholas Butowski, Penny K. Sneed, Mitchel S. Berger, Arie Perry, Joanna J. Phillips, David A. Solomon, Joseph F. Costello, Michael W. McDermott, Jeremy N. Rich, David R. Raleigh
SUMMARYMeningiomas arising from the meningothelial central nervous system lining are the most common primary intracranial tumors, and a significant cause of neurologic morbidity and mortality1. There are no effective medical therapies for meningioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::095a68adc866805ada6d7e17b4bf6510
https://doi.org/10.1101/2020.11.23.20237495
https://doi.org/10.1101/2020.11.23.20237495
Autor:
Vivian L. MacKay, Nicholas Burwick, Abdel Kareem Azab, Tomoka Nakamura, Melisa Ruiz-Gutierrez, Marilyn Sanchez-Bonilla, Michael Y. Zhang, Pilar de la Puente, Teresa S. Hyun, Akiko Shimamura, Jeffrey J. Delrow
Publikováno v:
Leukemia Research. 55:23-32
Dexamethasone (dex) induces apoptosis in multiple myeloma (MM) cells and is a frontline treatment for this disease. However resistance to dex remains a major challenge and novel treatment approaches are needed. We hypothesized that dex utilizes trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f21415ca9a3f68314145d726be146a
https://doi.org/10.1016/j.leukres.2017.01.007
https://doi.org/10.1016/j.leukres.2017.01.007
Autor:
R. Coleman Lindsley, Inga Hofmann, Sioban Keel, Colin C. Pritchard, Scott A. Coats, Tom Walsh, Rafael Márquez, Boglarka Gyurkocza, Mary Claire King, David A. Williams, Barbara Neistadt, Marshall S. Horwitz, Michael Y. Zhang, Melissa Forouhar, Christopher J. Mariani, Keith R. Loeb, Ryan Basom, Jeffrey J. Delrow, Ming K. Lee, Suleyman Gulsuner, Akiko Shimamura, Bradford S Schwartz, Janis L. Abkowitz, Marilyn Sanchez-Bonilla, Lucy A. Godley, Jane E. Churpek
Publikováno v:
Nature Genetics. 47:180-185
We report germline missense mutations in ETV6 segregating with the dominant transmission of thrombocytopenia and hematologic malignancy in three unrelated kindreds, defining a new hereditary syndrome featuring thrombocytopenia with susceptibility to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b813faef712e661ebfc35a76bb55e62
https://doi.org/10.1038/ng.3177
https://doi.org/10.1038/ng.3177