Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Michael Y, Gerner"'
Autor:
Sara B. Cohen, Courtney R. Plumlee, Lindsay Engels, Dat Mai, Tara A. Murray, Ana N. Jahn, Bridget Alexander, Jared L. Delahaye, Lauren M. Cross, Karolina Maciag, Sam Schrader, Kaitlin Durga, Elizabeth S. Gold, Alan Aderem, Michael Y. Gerner, Benjamin H. Gern, Alan H. Diercks, Kevin B. Urdahl
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
To investigate how host and pathogen diversity govern immunity against Mycobacterium tuberculosis (Mtb), we performed a large-scale screen of vaccine-mediated protection against aerosol Mtb infection using three inbred mouse strains [C57BL/6 (B6), C3
Externí odkaz:
https://doaj.org/article/8f1d5d9be6814725a222414224aa913c
Autor:
Caleb R. Stoltzfus, Ramya Sivakumar, Leo Kunz, Brandy E. Olin Pope, Elena Menietti, Dario Speziale, Roberto Adelfio, Marina Bacac, Sara Colombetti, Mario Perro, Michael Y. Gerner
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tumors are populated by a multitude of immune cell types with varied phenotypic and functional properties, which can either promote or inhibit anti-tumor responses. Appropriate localization and function of these cells within tumors is critical for pr
Externí odkaz:
https://doaj.org/article/162c262b779c407882480c615e849b6e
Autor:
Adam K. Glaser, Nicholas P. Reder, Ye Chen, Chengbo Yin, Linpeng Wei, Soyoung Kang, Lindsey A. Barner, Weisi Xie, Erin F. McCarty, Chenyi Mao, Aaron R. Halpern, Caleb R. Stoltzfus, Jonathan S. Daniels, Michael Y. Gerner, Philip R. Nicovich, Joshua C. Vaughan, Lawrence D. True, Jonathan T. C. Liu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Light-sheet microscopes are increasingly used for imaging cleared tissues, but have imposed constraints on sample geometries and protocols. Here the authors present a multi-immersion open-top light-sheet microscope to overcome these limitations and e
Externí odkaz:
https://doaj.org/article/90636626e5c14c7aacc695bf6808696a
Autor:
Caleb R. Stoltzfus, Jakub Filipek, Benjamin H. Gern, Brandy E. Olin, Joseph M. Leal, Yajun Wu, Miranda R. Lyons-Cohen, Jessica Y. Huang, Clarissa L. Paz-Stoltzfus, Courtney R. Plumlee, Thomas Pöschinger, Kevin B. Urdahl, Mario Perro, Michael Y. Gerner
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp - (2020)
Summary: Recently developed approaches for highly multiplexed imaging have revealed complex patterns of cellular positioning and cell-cell interactions with important roles in both cellular- and tissue-level physiology. However, tools to quantitative
Externí odkaz:
https://doaj.org/article/1df5a2d1e3124838b0964fff24a70671
Publikováno v:
Immunol Rev
Immune responses must be rapid, tightly orchestrated, and tailored to the encountered stimulus. Lymphatic vessels facilitate this process by continuously collecting immunological information (i.e., antigens, immune cells, and soluble mediators) about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1646c08454579ce77c637b7a7b7d30b2
https://doi.org/10.1111/imr.13046
https://doi.org/10.1111/imr.13046
Publikováno v:
Nature Immunology. 22:541-543
Single-cell technologies reveal the building blocks of secondary lymphoid organs, identifying Grem1(+) fibroblastic reticular cells (FRCs) as critical niche cells that contribute to resident dendritic cell homeostasis and T cell immunity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab645c08ce28d695b893dfb3856c2538
https://doi.org/10.1038/s41590-021-00924-2
https://doi.org/10.1038/s41590-021-00924-2
Autor:
Andrea J Radtke, Wolfgang Kastenmüller, Diego A Espinosa, Michael Y Gerner, Sze-Wah Tse, Photini Sinnis, Ronald N Germain, Fidel P Zavala, Ian A Cockburn
Publikováno v:
PLoS Pathogens, Vol 11, Iss 2, p e1004637 (2015)
Malaria infection begins when a female Anopheles mosquito injects Plasmodium sporozoites into the skin of its host during blood feeding. Skin-deposited sporozoites may enter the bloodstream and infect the liver, reside and develop in the skin, or mig
Externí odkaz:
https://doaj.org/article/fc456f521ca44b5994215478590319b0
Autor:
Jay Shendure, Takato Imaizumi, Prayag Murawala, Lindsey A. Barner, Kevin Bishop, Nicholas P. Reder, Pooja Balaram, Ramya Sivakumar, Xing Wei, Andrew K. Hempton, Shimpei I. Kubota, R. Clay Reid, Yating Yi, Gan Gao, Hongyi Huang, Jasmine Wilson, Adam K. Glaser, Jayaram Chandrashekar, Jonathan T. C. Liu, Elya Shamskhou, Lawrence D. True, Brian J. Beliveau, Hiroki R. Ueda, Hu Zhao, Luciano A. G. Lucas, Marko Pende, Etsuo A. Susaki, Hans Dodt, Li Xin, Karel Svoboda, Philip R. Nicovich, Robert Serafin, Caleb R. Stoltzfus, Michael Y. Gerner, Hoyin Lai, Eva Nichols, Emily Turschak
Light-sheet microscopy has emerged as the preferred means for high-throughput volumetric imaging of cleared tissues. However, there is a need for a user-friendly system that can address diverse imaging applications with varied requirements in terms o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7f98796627fd56a18f1fec8472f08c1
https://doi.org/10.21203/rs.3.rs-860253/v1
https://doi.org/10.21203/rs.3.rs-860253/v1
Autor:
Adam K. Glaser, Kevin W. Bishop, Lindsey A. Barner, Etsuo A. Susaki, Shimpei I. Kubota, Gan Gao, Robert B. Serafin, Pooja Balaram, Emily Turschak, Philip R. Nicovich, Hoyin Lai, Luciano A. G. Lucas, Yating Yi, Eva K. Nichols, Hongyi Huang, Nicholas P. Reder, Jasmine J. Wilson, Ramya Sivakumar, Elya Shamskhou, Caleb R. Stoltzfus, Xing Wei, Andrew K. Hempton, Marko Pende, Prayag Murawala, Hans-Ulrich Dodt, Takato Imaizumi, Jay Shendure, Brian J. Beliveau, Michael Y. Gerner, Li Xin, Hu Zhao, Lawrence D. True, R. Clay Reid, Jayaram Chandrashekar, Hiroki R. Ueda, Karel Svoboda, Jonathan T. C. Liu
Publikováno v:
Nat Methods
Light-sheet microscopy has emerged as the preferred means for high-throughput volumetric imaging of cleared tissues. However, there is a need for a flexible system that can address imaging applications with varied requirements in terms of resolution,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a14ef16f11808b273323bf3f73a75af
https://pubmed.ncbi.nlm.nih.gov/35545718
https://pubmed.ncbi.nlm.nih.gov/35545718
Autor:
Shahin Shafiani, Kevin B. Urdahl, Michael Y. Gerner, Benjamin H. Gern, Jared L. Delahaye, Sara B. Cohen, Courtney R. Plumlee
Publikováno v:
The Journal of Immunology. 203:807-812
Growing evidence suggests the outcome of Mycobacterium tuberculosis infection is established rapidly after exposure, but how the current tuberculosis vaccine, bacillus Calmette–Guérin (BCG), impacts early immunity is poorly understood. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e8f607f0213323277850d325abbfc2d
https://doi.org/10.4049/jimmunol.1900108
https://doi.org/10.4049/jimmunol.1900108