Zobrazeno 1 - 10
of 286
pro vyhledávání: '"Michael Way"'
Autor:
Yiqi Huang, Valter Bergant, Vincent Grass, Quirin Emslander, M. Sabri Hamad, Philipp Hubel, Julia Mergner, Antonio Piras, Karsten Krey, Alexander Henrici, Rupert Öllinger, Yonas M. Tesfamariam, Ilaria Dalla Rosa, Till Bunse, Gerd Sutter, Gregor Ebert, Florian I. Schmidt, Michael Way, Roland Rad, Andrew G. Bowie, Ulrike Protzer, Andreas Pichlmair
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Multiple omics analyzes of Vaccinia virus (VACV) infection have defined molecular characteristics of poxvirus biology. However, little is known about the monkeypox (mpox) virus (MPXV) in humans, which has a different disease manifestation de
Externí odkaz:
https://doaj.org/article/b2ed5b05f7224f76b575fd05ca07bceb
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Vaccinia virus assembly in the cytoplasm of infected cells involves the formation of a biconcave viral core inside the maturing viral particle. The boundary of the core is defined by a pseudohexagonal palisade layer, composed of trimers proj
Externí odkaz:
https://doaj.org/article/2135ede2aae540f587f2a82b8d633b69
Autor:
Angika Basant, Michael Way
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Vaccinia virus exiting from host cells activates Src/Abl kinases to phosphorylate A36, an integral membrane viral protein. Phosphorylated A36 binds the adaptors Nck and Grb2, which recruit N-WASP to activate Arp2/3-driven actin polymerizatio
Externí odkaz:
https://doaj.org/article/9bc74eedb898435eb0ea53846796e308
Autor:
Elena Sindram, Andrés Caballero-Oteyza, Naoko Kogata, Shaina Chor Mei Huang, Zahra Alizadeh, Laura Gámez-Díaz, Mohammad Reza Fazlollhi, Xiao Peng, Bodo Grimbacher, Michael Way, Michele Proietti
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 7 (2023)
Externí odkaz:
https://doaj.org/article/be44d41ed634488ebb81bb9fc0e62e5e
Autor:
Lopamudra Sadhu, Nikolaos Tsopoulidis, Md Hasanuzzaman, Vibor Laketa, Michael Way, Oliver T Fackler
Publikováno v:
eLife, Vol 12 (2023)
CD4 T cell activation induces nuclear and cytoplasmic actin polymerization via the Arp2/3 complex to activate cytokine expression and strengthen T cell receptor (TCR) signaling. Actin polymerization dynamics and filament morphology differ between nuc
Externí odkaz:
https://doaj.org/article/d00d81b2ab4d4bc9802cbc22defe29ad
Publikováno v:
PLoS Biology, Vol 21, Iss 3, p e3002005 (2023)
During its cytoplasmic replication, vaccinia virus assembles non-infectious spherical immature virions (IV) coated by a viral D13 lattice. Subsequently, IV mature into infectious brick-shaped intracellular mature virions (IMV) that lack D13. Here, we
Externí odkaz:
https://doaj.org/article/4a59616b1a694467835702683bc31bc5
Autor:
Angika Basant, Michael Way
Publikováno v:
eLife, Vol 11 (2022)
Phosphotyrosine (pTyr) motifs in unstructured polypeptides orchestrate important cellular processes by engaging SH2-containing adaptors to assemble complex signalling networks. The concept of phase separation has recently changed our appreciation of
Externí odkaz:
https://doaj.org/article/0b9efa0953ea4d23832d4751a25d364d
Autor:
China Williams, Alexandra Walsh, Valentina Vaglica, Aysegül Sirakaya, Manuela daSilva, Gemedo Dalle, Deborah Winterton, Wendy Annecke, Paul Smith, Paul J. Kersey, Michael Way, Alexandre Antonelli, Carly Cowell
Publikováno v:
Plants, People, Planet, Vol 2, Iss 5, Pp 535-545 (2020)
Societal Impact Statement Biodiversity loss is happening at an unprecedented rate. Understanding and protecting biodiversity has never been more urgent, and scientific research is key to this. Fair and transparent access and benefit sharing policies
Externí odkaz:
https://doaj.org/article/93f23a0e742942be92dc5c0b6eef7e4b
Autor:
Salvador Sampayo-Maldonado, Cesar A. Ordoñez-Salanueva, Efisio Mattana, Michael Way, Elena Castillo-Lorenzo, Patricia D. Dávila-Aranda, Rafael Lira-Saade, Oswaldo Téllez-Valdés, Norma I. Rodríguez-Arévalo, Cesar M. Flores-Ortiz, Tiziana Ulian
Publikováno v:
Plants, Vol 12, Iss 1, p 150 (2022)
Cedrela odorata is a native tree of economic importance, as its wood is highly demanded in the international market. In this work, the current and future distributions of C. odorata in Mexico under climate change scenarios were analyzed according to
Externí odkaz:
https://doaj.org/article/a8f5833e2b9c4fcb861ed51071c61047
Autor:
Adrian Pelin, Johann Foloppe, Julia Petryk, Ragunath Singaravelu, Marian Hussein, Florian Gossart, Victoria A. Jennings, Lawton J. Stubbert, Madison Foster, Christopher Storbeck, Antonio Postigo, Elena Scut, Brian Laight, Michael Way, Philippe Erbs, Fabrice Le Boeuf, John C. Bell
Publikováno v:
Molecular Therapy: Oncolytics, Vol 14, Iss , Pp 246-252 (2019)
Vaccinia virus (VACV) possesses a great safety record as a smallpox vaccine and has been intensively used as an oncolytic virus against various types of cancer over the past decade. Different strategies were developed to make VACV safe and selective
Externí odkaz:
https://doaj.org/article/5d24d17ce15143d1abecc60ad4722916