Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Michael Wannemuehler"'
Autor:
Lawrance Chandra, Dana C. Borcherding, Dawn Kingsbury, Todd Atherly, Yoko M. Ambrosini, Agnes Bourgois-Mochel, Wang Yuan, Michael Kimber, Yijun Qi, Qun Wang, Michael Wannemuehler, N. Matthew Ellinwood, Elizabeth Snella, Martin Martin, Melissa Skala, David Meyerholz, Mary Estes, Martin E. Fernandez-Zapico, Albert E. Jergens, Jonathan P. Mochel, Karin Allenspach
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-21 (2019)
Abstract Background Large animal models, such as the dog, are increasingly being used for studying diseases including gastrointestinal (GI) disorders. Dogs share similar environmental, genomic, anatomical, and intestinal physiologic features with hum
Externí odkaz:
https://doaj.org/article/f1fd34c1386747e0ad2d608f68d2611e
Publikováno v:
Antibiotics, Vol 11, Iss 8, p 1093 (2022)
The enormous and diverse population of microorganisms residing in the digestive tracts of humans and animals influence the development, regulation, and function of the immune system. Recently, the understanding of the association between autoimmune d
Externí odkaz:
https://doaj.org/article/7af521b7a8fa4e4b849ab6ea3a23126f
Autor:
Zahra Davoudi, Nathan Peroutka-Bigus, Bryan Bellaire, Albert Jergens, Michael Wannemuehler, Qun Wang
Publikováno v:
Marine Drugs, Vol 19, Iss 5, p 282 (2021)
Intestinal organoids can be used as an ex vivo epithelial model to study different drug delivery effects on epithelial cells’ luminal surface. In this study, the impact of surface charge on the delivery of 5-ASA loaded PLGA nanoparticles into the l
Externí odkaz:
https://doaj.org/article/6ff5f694d0414740bc57b5b231479060
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191517 (2018)
The intestinal epithelium of the gastrointestinal (GI) tract constantly renews itself to absorb nutrients and provide protection for the body from the outside world. Since the intestinal epithelium is constantly exposed to various chemicals and dieta
Externí odkaz:
https://doaj.org/article/9082037e63fa41a3b5574f7cc00db850
Autor:
John C Christiansen, Luman Liu, Prakash Kshirsagar, Emad Wafa, Shailendra Gautam, Abhijit Aithal, Mansi Gulati, Sushil Kumar, Joyce Solheim, Surinder Batra, Aliasger Salem, Maneesh Jain, Michael Wannemuehler, Balaji Narasimhan
Publikováno v:
The Journal of Immunology. 208:123.13-123.13
Patients diagnosed with pancreatic ductal adenocarcinoma (PDAC) have an unrelentingly poor prognosis, in part because of the lack of neoantigen targets associated with PDAC tumors. However, another approach would be to take advantage of differentiall
Autor:
Yijun, Qi, Jo, Lohman, Kaitlin M, Bratlie, Nathan, Peroutka-Bigus, Bryan, Bellaire, Michael, Wannemuehler, Kyoung-Jin, Yoon, Terrence A, Barrett, Qun, Wang
Publikováno v:
J Biomed Mater Res A
Vitamin C (ascorbic acid) and vitamin B(3) (niacin) have been extensively studied since the 20th century. In the area of stem cell biology, vitamin C has shown its direct impact towards homeostasis and epigenetic changes.(1) Vitamin B(3) aids in main
Autor:
Zahra, Davoudi, Nathan, Peroutka-Bigus, Bryan, Bellaire, Michael, Wannemuehler, Terrence A, Barrett, Balaji, Narasimhan, Qun, Wang
Publikováno v:
Journal of biomedical materials research. Part A. 106(4)
Inflammatory bowel disease (IBD) causes inflammation to the gastrointestinal tract. Local administration of anti-inflammatory drugs such as 5-aminosalicylic acid (5-ASA) can alleviate the symptoms of IBD. The application of nanoparticles for IBD trea
Autor:
Lucas Huntimer, Kathleen Ross, Ross Darling, Amanda Ramer-Tait, Balaji Narasimhan, Michael Wannemuehler
Publikováno v:
The Journal of Immunology. 190:177.16-177.16
Bioerodible nanoparticles have been shown to be useful as vaccine delivery vehicles. Previous work from this laboratory has shown that polyanhydride nanoparticles (NPs) can be used as an effective platform delivery system with the ability to modulate
Publikováno v:
The Journal of Immunology. 190:179.18-179.18
Previous studies have shown that the use of the polyanhydride nanoparticle (NP) vaccine platform provides innate immunomodulatory activity while also controlling antigen release kinetics that enhance antibody-mediated immunity. The goal of this proje
Autor:
Ross Darling, Lucas Huntimer, Kathleen Ross, Amanda Ramer-Tait, Balaji Narasimhan, Michael Wannemuehler
Publikováno v:
The Journal of Immunology. 190:132.15-132.15
Immunotherapies designed to direct the immune system to elimate malignancies is a growing area of research aimed at providing a safe and effective alternative and/or adjunct therapy to chemotherapeutic and surgical interventions. These approaches req