Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Michael W. Sereda"'
Autor:
Robert Fledrich, Dagmar Akkermann, Vlad Schütza, Tamer A. Abdelaal, Doris Hermes, Erik Schäffner, M. Clara Soto-Bernardini, Tilmann Götze, Axel Klink, Kathrin Kusch, Martin Krueger, Theresa Kungl, Clara Frydrychowicz, Wiebke Möbius, Wolfgang Brück, Wolf C. Mueller, Ingo Bechmann, Michael W. Sereda, Markus H. Schwab, Klaus-Armin Nave, Ruth M. Stassart
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Onion bulbs are a hallmark of demyelinating peripheral neuropathies. Here the authors identify Neuregulin-1 type I expression in Schwann cells as an essential mechanism involved in the formation of these characteristic structures.
Externí odkaz:
https://doaj.org/article/d62e39531a3348db81bc0e371f8388cc
Autor:
Giovanna Sociali, Davide Visigalli, Thomas Prukop, Ilaria Cervellini, Elena Mannino, Consuelo Venturi, Santina Bruzzone, Michael W. Sereda, Angelo Schenone
Publikováno v:
Neurobiology of Disease, Vol 95, Iss , Pp 145-157 (2016)
Charcot-Marie-Tooth 1A (CMT1A) is a demyelinating hereditary neuropathy for which pharmacological treatments are not yet available. An abnormally high intracellular Ca2+ concentration was observed in Schwann cells (SC) from CMT1A rats, caused by the
Externí odkaz:
https://doaj.org/article/e0b812583bae437a95e6d60c5edf1094
Autor:
Robert Fledrich, Dagmar Akkermann, Vlad Schütza, Tamer A. Abdelaal, Doris Hermes, Erik Schäffner, M. Clara Soto-Bernardini, Tilmann Götze, Axel Klink, Kathrin Kusch, Martin Krueger, Theresa Kungl, Clara Frydrychowicz, Wiebke Möbius, Wolfgang Brück, Wolf C. Mueller, Ingo Bechmann, Michael W. Sereda, Markus H. Schwab, Klaus-Armin Nave, Ruth M. Stassart
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-2 (2019)
Michael W. Sereda was incorrectly associated with the Department of Cellular Neurophysiology, Hanover Medical School, Carl-Neuberg-Str. 1, 30625 Hanover, Germany. The correct affiliations for Michael W. Sereda are Department of Neurogenetics, Max-Pla
Externí odkaz:
https://doaj.org/article/97556eb535534b8791b4801491656226
Autor:
Gerd Meyer zu Horste, Timo A. Miesbach, Johanna I. Muller, Robert Fledrich, Ruth M. Stassart, Bernd C. Kieseier, Michael P. Coleman, Michael W. Sereda
Publikováno v:
Neurobiology of Disease, Vol 42, Iss 1, Pp 1-8 (2011)
Charcot-Marie-Tooth disease (CMT) is the most common inherited neuropathy and a duplication of the peripheral myelin protein of 22 kDa (PMP22) gene causes the most frequent subform CMT1A. Clinical impairments are determined by the amount of axonal lo
Externí odkaz:
https://doaj.org/article/deaaff98cb1a46f29740b2f3f9ce1367
Autor:
Doris Krauter, Daniela Stausberg, Timon J Hartmann, Stefan Volkmann, Theresa Kungl, David A Rasche, Gesine Saher, Robert Fledrich, Ruth M Stassart, Klaus-Armin Nave, Sandra Goebbels, David Ewers, Michael W Sereda
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 3, Pp 616-640 (2024)
Abstract Haplo-insufficiency of the gene encoding the myelin protein PMP22 leads to focal myelin overgrowth in the peripheral nervous system and hereditary neuropathy with liability to pressure palsies (HNPP). Conversely, duplication of PMP22 causes
Externí odkaz:
https://doaj.org/article/7fd4960236094ab48972800c5f7528ba
Autor:
Sean Ekins, Nadia K. Litterman, Renée J.G. Arnold, Robert W. Burgess, Joel S. Freundlich, Steven J. Gray, Joseph J. Higgins, Brett Langley, Dianna E. Willis, Lucia Notterpek, David Pleasure, Michael W. Sereda, Allison Moore
Publikováno v:
F1000Research, Vol 4 (2015)
This brief review of current research progress on Charcot-Marie-Tooth (CMT) disease is a summary of discussions initiated at the Hereditary Neuropathy Foundation (HNF) scientific advisory board meeting on November 7, 2014. It covers recent published
Externí odkaz:
https://doaj.org/article/3547c770fb444cc882536cb3aeb4f6a8
Autor:
Sophie B Siems, Olaf Jahn, Maria A Eichel, Nirmal Kannaiyan, Lai Man N Wu, Diane L Sherman, Kathrin Kusch, Dörte Hesse, Ramona B Jung, Robert Fledrich, Michael W Sereda, Moritz J Rossner, Peter J Brophy, Hauke B Werner
Publikováno v:
eLife, Vol 9 (2020)
Proteome and transcriptome analyses aim at comprehending the molecular profiles of the brain, its cell-types and subcellular compartments including myelin. Despite the relevance of the peripheral nervous system for normal sensory and motor capabiliti
Externí odkaz:
https://doaj.org/article/0ee8234d2e754139a9f492fe22e31c0d
Autor:
Doris Krauter, Timon J Hartmann, Stefan Volkmann, Theresa Kungl, Daniela Stausberg, Gesine Saher, Robert Fledrich, Ruth M Stassart, Klaus-Armin Nave, Sandra Goebbels, David Ewers, Michael W Sereda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d7dfe768b17d6ae26c7d3134fddee26
https://doi.org/10.15252/rc.2023410581
https://doi.org/10.15252/rc.2023410581
Autor:
Sandra Kleinecke, Sarah Richert, Livia de Hoz, Britta Brügger, Theresa Kungl, Ebrahim Asadollahi, Susanne Quintes, Judith Blanz, Rhona McGonigal, Kobra Naseri, Michael W Sereda, Timo Sachsenheimer, Christian Lüchtenborg, Wiebke Möbius, Hugh Willison, Myriam Baes, Klaus-Armin Nave, Celia Michèle Kassmann
Publikováno v:
eLife, Vol 6 (2017)
Impairment of peripheral nerve function is frequent in neurometabolic diseases, but mechanistically not well understood. Here, we report a novel disease mechanism and the finding that glial lipid metabolism is critical for axon function, independent
Externí odkaz:
https://doaj.org/article/278b7784adc34b6b9b3600532a3126a2
Publikováno v:
Mol Cell
The product of hexokinase (HK) enzymes, glucose-6-phosphate, can be metabolized through glycolysis or directed to alternative metabolic routes, such as the pentose phosphate pathway (PPP) to generate anabolic intermediates. HK1 contains an N-terminal