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pro vyhledávání: '"Michael W. Meanwell"'
Autor:
Thirupathi Nuligonda, Gautam Kumar, Jason W. Wang, Dinithi Rajapaksha, Ismael A. Elayan, Ramiz Demir, Neil J. Meanwell, Sherrie F. Wang, Lara K. Mahal, Alex Brown, Michael W. Meanwell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract C4ʹ-modified nucleoside analogues continue to attract global attention for their use in antiviral drug development and oligonucleotide-based therapeutics. However, current approaches to C4ʹ-modified nucleoside analogues still involve lengt
Externí odkaz:
https://doaj.org/article/d7aee5e037d04b6daf31add4ec8c4aae
Publikováno v:
Chemical Communications.
We report a mild, electrochemical trihydrodefluorination (e-THDF) for breaking highly stable C–F bonds in trifluoromethyl arenes to form the corresponding methyl arene products.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4559b0512080cbb53cb11f816d3d6cf7
https://doi.org/10.1039/d3cc01850d
https://doi.org/10.1039/d3cc01850d