Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Michael W. McLane"'
Autor:
Solange N Eloundou, JiYeon Lee, Dan Wu, Jun Lei, Mia C Feller, Maide Ozen, Yan Zhu, Misun Hwang, Bei Jia, Han Xie, Julia L Clemens, Michael W McLane, Samar AlSaggaf, Nita Nair, Marsha Wills-Karp, Xiaobin Wang, Ernest M Graham, Ahmet Baschat, Irina Burd
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214951 (2019)
Exposure to intrauterine inflammation (IUI) is associated with short- and long-term adverse perinatal outcomes. However, little data exist on utilizing placenta to prognosticate fetal injury in this scenario. Our study aimed to utilize imaging modali
Externí odkaz:
https://doaj.org/article/3e6ec767d67e4bc0b5126cf729f140c7
Autor:
Michael W. McLane, Jun Lei, Hongxi Zhao, Irina Burd, Mia C. Feller, Julia L. Clemens, Yan Zhu, Bei Jia, Li Xie, Maide Ozen, Andreas Facciabene, Hattan Arif, Lu Zong
Publikováno v:
Reproductive Sciences. 27:1465-1476
The objective of this study was to determine if mouse bone marrow-derived mesenchymal stem cells (BMMSCs) ameliorate preterm birth and perinatal brain injury induced by intrauterine inflammation (IUI). A mouse model of IUI-induced perinatal brain inj
Autor:
Jun Lei, Michael W. McLane, Irina Burd, Su Li, Quan Na, Bei Jia, Ji Yeon Lee, Anna Chudnovets, Jie Dong, Na Shin
Publikováno v:
Biology of Reproduction. 101:1046-1055
Maternal inflammation (MI) is associated with many adverse perinatal outcomes. The placenta plays a vital role in mediating maternal-fetal resource allocation. Studies have shown that MI contributes to placental dysfunction, which then leads to adver
Publikováno v:
Placenta. 69:86-91
Introduction We investigated the feasibility of dynamic glucose enhanced (DGE) MRI in accessing placental function in a mouse model of intrauterine inflammatory injury (IUI). DGE uses the glucose chemical exchange saturation transfer (glucoCEST) effe
Autor:
Rayyan Rozzah, Michael W. McLane, Hattan Arif, Ghada Al Yousif, Hongxi Zhao, Dan Wu, Ahmad Almalki, Wenyu Zhong, Jun Lei, Nader Alhejaily, Irina Burd
Publikováno v:
Reproductive Sciences. 25:1175-1185
Fetal brain injury induced by intrauterine inflammation is a major risk factor for adverse neurological outcomes, including cerebral palsy, cognitive dysfunction, and behavioral disabilities. There are no adequate therapies for neuronal protection to
Autor:
Michael W. McLane, Jun Lei, James Maylie, Wendy W. Wu, Han Xie, Kyle D. Hart, Leonardo Pereira, Melissa H. Kelley, Irina Burd
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-8 (2017)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Recent evidence suggests that exposure to intrauterine inflammation causes acute fetal brain injury and is linked to a spectrum of neurobehavioral disorders. In a rodent model of intrauterine inflammation induced by lipopolysaccharide (LPS
Autor:
Quan Na, Irina Burd, Kimberly Jones-Beatty, Su Li, Maide Ozen, Jun Lei, Na E. Shin, Michael W. McLane, Jie Dong, Bei Jia, Ji Yeon Lee
Publikováno v:
Journal of Pineal Research. 67
Melatonin has been shown to reduce oxidative stress and mitigate hypercoagulability. We hypothesized that maternally administered melatonin may reduce placental oxidative stress and hypercoagulability associated with exposure to intrauterine inflamma
Autor:
Hongxi, Zhao, Li, Xie, Julia L, Clemens, Lu, Zong, Michael W, McLane, Hattan, Arif, Mia C, Feller, Bei, Jia, Yan, Zhu, Andreas, Facciabene, Maide, Ozen, Jun, Lei, Irina, Burd
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.). 27(7)
The objective of this study was to determine if mouse bone marrow-derived mesenchymal stem cells (BMMSCs) ameliorate preterm birth and perinatal brain injury induced by intrauterine inflammation (IUI). A mouse model of IUI-induced perinatal brain inj
Autor:
Ji Yeon Lee, Haengseok Song, Mira Park, Michael W. McLane, Irina Burd, Jun Lei, Oyunbileg Dash, Jong Yun Hwang, Na E. Shin
Publikováno v:
American Journal of Reproductive Immunology. 82
Problem Maternal inflammation leads to preterm birth and perinatal brain injury. Melatonin, through its anti-inflammatory effects, has been shown to be protective against inflammation-induced perinatal adverse effects. However, the immunomodulatory e
Autor:
Quan Na, Jie Dong, Irina Burd, Ji Yeon Lee, Michael W. McLane, Su Li, Jun Lei, Na E. Shin, Anna Chudnovets, Christopher M. Novak
Publikováno v:
Journal of reproductive immunology. 133
Problem Exposure to systemic maternal inflammation (i.e., maternal sepsis, influenza, human immunodeficiency virus, or pyelonephritis) and intrauterine (IU) inflammation (i.e., chorioamnionitis or preterm labor) have been associated with adverse peri