Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Michael W Y Chan"'
Autor:
Mita T M T Tran, Kun-Tu Yeh, Yu-Ming Chuang, Po-Yen Hsu, Jie-Ting Low, Himani Kumari, Yu-Ting Lee, Yin-Chen Chen, Wan-Hong Huang, Hongchuan Jin, Shu-Hui Lin, Michael W Y Chan
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250499 (2021)
Gastric cancer is one of the leading causes of cancer death worldwide. Previous studies demonstrated that activation of STAT3 is crucial for the development and progression of gastric cancer. However, the role of STAT3 in neuronal related gene methyl
Externí odkaz:
https://doaj.org/article/f4830aa23b334a6895b7ca5a976c1d9a
Autor:
Jing-Siang Jhang, Hanoch Livneh, Shu-Yi Yang, Hui-Ju Huang, Michael W Y Chan, Chia-Chou Yeh, Tzung-Yi Tsai
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
ObjectivesPatients with type 2 diabetes have a higher risk of colorectal cancer (CRC), but whether Chinese herbal medicines (CHMs) can reduce this risk is unknown. This study investigated the effect that CHMs have on CRC risk in patients with type 2
Externí odkaz:
https://doaj.org/article/06b837f75bdc4e67807e089f201a53b2
Autor:
Kuo-Liang Wei, Jian-Liang Chou, Yin-Chen Chen, Hongchuan Jin, Yu-Min Chuang, Cheng-Shyong Wu, Michael W Y Chan
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218338 (2019)
Gastric cancer is a leading cause of cancer worldwide. Our previous studies showed that aberrant activation of JAK/STAT3 signaling confer epigenetically silences STAT3 target genes in gastric cancer. To further investigate the clinical significance o
Externí odkaz:
https://doaj.org/article/d3e70c3b5fea42f9abdab44c7795123b
Autor:
Chi-Chen Lu, Cheng-Huang Shen, Chia-Bin Chang, Hsiao-Yen Hsieh, Jiann-Der Wu, Ling-Huei Tseng, Dennis W Hwang, Syue-Yi Chen, Shu-Fen Wu, Michael W Y Chan, Cheng-Da Hsu
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 64-73 (2016)
Abstract Alternative intravesical agents are required to overcome the side effects currently associated with the treatment of bladder cancer. This study used an orthotopic bladder cancer mouse model to evaluate Guizhi Fuling Wan (GFW) as an intravesi
Externí odkaz:
https://doaj.org/article/3deefdd09ab344a888d2445c03d3deb3
Autor:
Frank H C Cheng, Baltazar D Aguda, Je-Chiang Tsai, Marek Kochańczyk, Jora M J Lin, Gary C W Chen, Hung-Cheng Lai, Kenneth P Nephew, Tzy-Wei Hwang, Michael W Y Chan
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116050 (2014)
Accumulating data indicate that cancer stem cells contribute to tumor chemoresistance and their persistence alters clinical outcome. Our previous study has shown that ovarian cancer may be initiated by ovarian cancer initiating cells (OCIC) character
Externí odkaz:
https://doaj.org/article/09ff0015f6134dfca09ab83ea71acb7d
Autor:
Pritam Banerjee, Gobinda Dey, Jyoti Prakash Maity, Kathryn A. Stewart, Raju Kumar Sharma, Michael W. Y. Chan, Kuanhsuen Lee, Chien‐Yen Chen
Publikováno v:
Ecology and Evolution, Vol 14, Iss 4, Pp n/a-n/a (2024)
Abstract The cryptic invasion of golden apple snails (Pomacea canaliculata and P. maculata) in Taiwan has caused significant ecological and economical damage over the last few decades, however, their management remains difficult due to inadequate tax
Externí odkaz:
https://doaj.org/article/af4af4b327bb4464b9d5159764a4e7b5
Autor:
Brian A Kennedy, Daniel E Deatherage, Fei Gu, Binhua Tang, Michael W Y Chan, Kenneth P Nephew, Tim H-M Huang, Victor X Jin
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22606 (2011)
Deregulation of the transforming growth factor-β (TGFβ) signaling pathway in epithelial ovarian cancer has been reported, but the precise mechanism underlying disrupted TGFβ signaling in the disease remains unclear. We performed chromatin immunopr
Externí odkaz:
https://doaj.org/article/8b4b29ea02c0411c966c546bdf736d90
Autor:
Mita T. M. T. Tran, Fu-Chen Kuo, Jie-Ting Low, Yu-Ming Chuang, Sofia Sultana, Wen-Long Huang, Zhe-Young Lin, Guan-Ling Lin, Chia-Fang Wu, Sih-Syuan Li, Jau-Ling Suen, Chih-Hsing Hung, Ming-Tsang Wu, Michael W. Y. Chan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Recent experimental and observational research has suggested that childhood allergic asthma and other conditions may be the result of prenatal exposure to environmental contaminants, such as di-(2-ethylhexyl) phthalate (DEHP). In a previous
Externí odkaz:
https://doaj.org/article/ecb4fd85fba449b5b3924902901cdde9
Autor:
Bonan Chen, Xiaoli Liu, Peiyao Yu, Fuda Xie, Johnny S. H. Kwan, Wai Nok Chan, Canbin Fang, Jinglin Zhang, Alvin H. K. Cheung, Chit Chow, Gloria W. M. Leung, Kam Tong Leung, Shihua Shi, Bin Zhang, Shouyu Wang, Dazhi Xu, Kaili Fu, Chi Chun Wong, William K. K. Wu, Michael W. Y. Chan, Patrick M. K. Tang, Chi Man Tsang, Kwok Wai Lo, Gary M. K. Tse, Jun Yu, Ka Fai To, Wei Kang
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 11, Pp n/a-n/a (2023)
Abstract Background Gastric cancer (GC) is one of the most common tumours in East Asia countries and is associated with Helicobacter pylori infection. H. pylori utilizes virulence factors, CagA and VacA, to up‐regulate pro‐inflammatory cytokines
Externí odkaz:
https://doaj.org/article/7bfa61a822b64b09a39959da5d928f18
Autor:
Yuan-Hong Jiang, Yu-Shu Liu, Yu-Chung Wei, Jia-Fong Jhang, Hann-Chorng Kuo, Hsin-Hui Huang, Michael W. Y. Chan, Guan-Ling Lin, Wen-Chi Cheng, Shu-Chuan Lin, Hung-Jung Wang
Publikováno v:
Diagnostics, Vol 14, Iss 5, p 468 (2024)
Bladder cancer (BCa) is a significant health issue and poses a healthcare burden on patients, highlighting the importance of an effective detection method. Here, we developed a urine DNA methylation diagnostic panel for distinguishing between BCa and
Externí odkaz:
https://doaj.org/article/f2e49546d01a4774b53ea3015fda9dd4