Zobrazeno 1 - 10
of 337
pro vyhledávání: '"Michael W Schwartz"'
Autor:
Chelsea L Faber, Jennifer D Deem, Bao Anh Phan, Tammy P Doan, Kayoko Ogimoto, Zaman Mirzadeh, Michael W Schwartz, Gregory J Morton
Publikováno v:
eLife, Vol 10 (2021)
The brain plays an essential role in driving daily rhythms of behavior and metabolism in harmony with environmental light–dark cycles. Within the brain, the dorsomedial hypothalamic nucleus (DMH) has been implicated in the integrative circadian con
Externí odkaz:
https://doaj.org/article/de654672db84412caa24254afde95e76
Autor:
Jennifer D Deem, Chelsea L Faber, Christian Pedersen, Bao Anh Phan, Sarah A Larsen, Kayoko Ogimoto, Jarrell T Nelson, Vincent Damian, Megan A Tran, Richard D Palmiter, Karl J Kaiyala, Jarrad M Scarlett, Michael R Bruchas, Michael W Schwartz, Gregory J Morton
Publikováno v:
eLife, Vol 9 (2020)
To maintain energy homeostasis during cold exposure, the increased energy demands of thermogenesis must be counterbalanced by increased energy intake. To investigate the neurobiological mechanisms underlying this cold-induced hyperphagia, we asked wh
Externí odkaz:
https://doaj.org/article/3bf1e03edc9c473196f7e1c90cbf2a36
Autor:
Sanshiro Tateya, Norma Rizzo-De Leon, Andrew M Cheng, Brian P Dick, Woo Je Lee, Madeleine L Kim, Kevin O'Brien, Gregory J Morton, Michael W Schwartz, Francis Kim
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215601 (2019)
During periods in which glucose absorption from the gastrointestinal (GI) tract is insufficient to meet body requirements, hepatic gluconeogenesis plays a key role to maintain normal blood glucose levels. The current studies investigated the role in
Externí odkaz:
https://doaj.org/article/149227ddf9234b0385ca67ec70389f22
Autor:
Kendra L. Francis, Hengqi B. Zheng, David L. Suskind, Taylor A. Murphree, Bao Anh Phan, Emily Quah, Aarun S. Hendrickson, Xisheng Zhou, Mason Nuding, Alexandra S. Hudson, Miklos Guttman, Gregory J. Morton, Michael W. Schwartz, Kimberly M. Alonge, Jarrad M. Scarlett
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The intestinal extracellular matrix (ECM) helps maintain appropriate tissue barrier function and regulate host-microbial interactions. Chondroitin sulfate- and dermatan sulfate-glycosaminoglycans (CS/DS-GAGs) are integral components of the i
Externí odkaz:
https://doaj.org/article/079a8bfa3048479493c38f401f2d9cdd
Autor:
Michael W. Schwartz
Publikováno v:
Frontiers in Conservation Science, Vol 5 (2024)
The Uganda Carnivore Program (UCP), located in Queen Elizabeth National Park (QENP), has—among other large carnivore research and conservation measures—engaged in human-carnivore conflict mitigation and prevention efforts since 2015. UCP’s expe
Externí odkaz:
https://doaj.org/article/e7665b72935e4f828cfa46527197b2c9
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119391 (2015)
Survival of free-living animals depends on the ability to maintain core body temperature in the face of rapid and dramatic changes in their thermal environment. If food intake is not adjusted to meet the changing energy demands associated with change
Externí odkaz:
https://doaj.org/article/69968a4b36d74999925016589ae6bbee
Autor:
Allison Wanting Xu, Christopher B Kaelin, Gregory J Morton, Kayoko Ogimoto, Kimber Stanhope, James Graham, Denis G Baskin, Peter Havel, Michael W Schwartz, Gregory S Barsh
Publikováno v:
PLoS Biology, Vol 3, Iss 12, p e415 (2005)
Normal aging in humans and rodents is accompanied by a progressive increase in adiposity. To investigate the role of hypothalamic neuronal circuits in this process, we used a Cre-lox strategy to create mice with specific and progressive degeneration
Externí odkaz:
https://doaj.org/article/4114ec43dfc945be96b9873c0a23960f
Publikováno v:
Diabetes. 72:547-556
The glucose homeostasis system ensures that the circulating glucose level is maintained within narrow physiological limits both in the fasting (or basal) state and following a nutrient challenge. Although glucose homeostasis is traditionally conceptu
Publikováno v:
Diabetes Care
“Relative hypoglycemia” is an often-overlooked complication of diabetes characterized by an increase in the glycemic threshold for detecting and responding to hypoglycemia. The clinical relevance of this problem is linked to growing evidence that
Autor:
James S, Krinsley, Michael, Brownlee, Michael W, Schwartz, Gregory, Roberts, Jean-Charles, Preiser, Peter, Rule, Guillermo E, Umpierrez, Irl B, Hirsch
Publikováno v:
The Lancet Diabetes & Endocrinology. 10:555-557