Biophysical characterization and a roadmap towards the NMR solution structure of G0S2, a key enzyme in non-alcoholic fatty liver disease.

Autor: Michael W Moran, Elizabeth P Ramirez, James D Zook, Alicia M Saarinen, Bobby Baravati, Matthew R Goode, Vasiliki Laloudakis, Emily K Kaschner, Tien L Olson, Felicia M Craciunescu, Debra T Hansen, Jun Liu, Petra Fromme

Publikováno v: PLoS ONE, Vol 16, Iss 7, p e0249164 (2021)

In the United States non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease, affecting an estimated 80 to 100 million people. It occurs in every age group, but predominantly in people with risk factors such as obes

Externí odkaz: https://doaj.org/article/df709f94f5d2437182ca1909b6b7e4f4

X-ray Emission Spectroscopy at X-ray Free Electron Lasers: Limits to Observation of the Classical Spectroscopic Response for Electronic Structure Analysis

Autor: Alex Schaffer, Raymond G. Sierra, Christopher Kupitz, Gerald T. Seidler, Yulia Pushkar, Nadia A. Zatsepin, Jay How Yang, Juraj Knoska, Oleksandr Yefanov, Jose Meza Aguilar, Dominik Oberthür, Gihan K. Ketawala, Daniel A. Hartzler, Stella Lisova, Salah Awel, Saša Bajt, Raimund Fromme, Brendan Sullivan, Michael Heymann, Marc Messerschmidt, Scott Jensen, Henry N. Chapman, Richard A. Kirian, Xuanxuan Li, Victoria Mazalova, Mark S. Hunter, Sébastien Boutet, Garrett Nelson, Jose M. Martin-Garcia, Uwe Weierstall, P. Lourdu Xavier, Natalie Vaughn, Richard Bean, Shibom Basu, Max O. Wiedorn, Andrew Aquila, Matthias Frank, Chelsie E. Conrad, Valerio Mariani, Petra Fromme, Michael W. Moran, Mengning Liang, Thomas D. Grant

Publikováno v: The Journal of Physical Chemistry Letters
The journal of physical chemistry letters 10(3), 441-446 (2019). doi:10.1021/acs.jpclett.8b03595

The journal of physical chemistry letters 10(3), 441 - 446 (2019). doi:10.1021/acs.jpclett.8b03595
X-ray free electron lasers (XFELs) provide ultrashort intense X-ray pulses suitable to probe electron dynamics but can also induce a multitude of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3c2d11fe4eb2c2a4f898459eb2fb0f