Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michael W M, Kühn"'
Autor:
Frank G. Rücker, Lars Bullinger, Sibylle Cocciardi, Sabrina Skambraks, Tamara J. Luck, Daniela Weber, Julia Krzykalla, Ema Pozek, Isabelle Schneider, Andrea Corbacioglu, Verena I. Gaidzik, Annika Meid, Sophia Aicher, Frank Stegelmann, Anika Schrade, Frauke Theis, Walter Fiedler, Helmut R. Salih, Gerald Wulf, Hans Salwender, Thomas Schroeder, Katharina S. Götze, Michael W. M. Kühn, Michael Lübbert, Richard F. Schlenk, Axel Benner, Felicitas Thol, Michael Heuser, Arnold Ganser, Hartmut Döhner, Konstanze Döhner
Publikováno v:
Blood Advances, Vol 8, Iss 23, Pp 6067-6080 (2024)
Abstract: Measurable residual disease (MRD) monitoring in acute myeloid leukemia (AML) with an FLT3 internal tandem duplication (FLT3-ITDpos) has been hampered by the broad heterogeneity of ITD mutations. Using our recently developed FLT3-ITD paired-
Externí odkaz:
https://doaj.org/article/a1ba49620d1d47c78a4a31023fcd9129
Autor:
Frank G. Rücker, Andrea Corbacioglu, Julia Krzykalla, Sibylle Cocciardi, Claudia Lengerke, Ulrich Germing, Gerald Wulf, Maisun A. Samra, Lino L. Teichmann, Michael Lübbert, Michael W. M. Kühn, Martin Bentz, Jörg Westermann, Lars Bullinger, Verena I. Gaidzik, Annika Meid, Sophia Aicher, Frank Stegelmann, Daniela Weber, Anika Schrade, Felicitas Thol, Michael Heuser, Arnold Ganser, Axel Benner, Hartmut Döhner, Konstanze Döhner, for the German‐Austrian Acute Myeloid Leukemia Study Group (AMLSG)
Publikováno v:
HemaSphere, Vol 8, Iss 7, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/57b77f726894460c9984828c82423457
Autor:
Nuria Tubío-Santamaría, Ashok Kumar Jayavelu, Tina M. Schnoeder, Theresa Eifert, Chen-Jen Hsu, Florian Perner, Qirui Zhang, Daniela V. Wenge, Fynn M. Hansen, Joanna M. Kirkpatrick, Nidhi Jyotsana, Steven W. Lane, Björn von Eyss, Aniruddha J. Deshpande, Michael W. M. Kühn, Juerg Schwaller, Clemens Cammann, Ulrike Seifert, Frédéric Ebstein, Elke Krüger, Andreas Hochhaus, Michael Heuser, Alessandro Ori, Matthias Mann, Scott A. Armstrong, Florian H. Heidel
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-21 (2023)
Abstract Pharmacologic targeting of chromatin-associated protein complexes has shown significant responses in KMT2A-rearranged (KMT2A-r) acute myeloid leukemia (AML) but resistance frequently develops to single agents. This points to a need for thera
Externí odkaz:
https://doaj.org/article/32a44bd3490c43d78d23fc64b13aaac5
Autor:
Nawid Albinger, Rita Pfeifer, Marcus Nitsche, Sarah Mertlitz, Julia Campe, Katja Stein, Hermann Kreyenberg, Ralf Schubert, Melissa Quadflieg, Dina Schneider, Michael W. M. Kühn, Olaf Penack, Congcong Zhang, Nina Möker, Evelyn Ullrich
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 4, Pp 1-9 (2022)
Abstract Acute myeloid leukemia (AML) is a malignant disorder derived from neoplastic myeloid progenitor cells characterized by abnormal proliferation and differentiation. Although novel therapeutics have recently been introduced, AML remains a thera
Externí odkaz:
https://doaj.org/article/6fc0ca3995ea457188b66816b74dd4ba
Autor:
Hartmut Döhner, Daniela Weber, Julia Krzykalla, Walter Fiedler, Gerald Wulf, Helmut Salih, Michael Lübbert, Michael W. M. Kühn, Thomas Schroeder, Hans Salwender, Katharina Götze, Jörg Westermann, Lars Fransecky, Karin Mayer, Bernd Hertenstein, Mark Ringhoffer, Hans-Joachim Tischler, Sigrid Machherndl-Spandl, Anika Schrade, Peter Paschka, Verena I. Gaidzik, Frauke Theis, Felicitas Thol, Michael Heuser, Richard F. Schlenk, Lars Bullinger, Maral Saadati, Axel Benner, Richard Larson, Richard Stone, Konstanze Döhner, Arnold Ganser
Publikováno v:
Blood Advances. 6:5345-5355
We conducted a single-arm, phase 2 trial (German-Austrian Acute Myeloid Leukemia Study Group [AMLSG] 16-10) to evaluate midostaurin with intensive chemotherapy followed by allogeneic hematopoietic-cell transplantation (HCT) and a 1-year midosta urin
Autor:
Hartmut Döhner, Daniela Weber, Julia Krzykalla, Walter Fiedler, Michael W M Kühn, Thomas Schroeder, Karin Mayer, Michael Lübbert, Mohammed Wattad, Katharina Götze, Lars Fransecky, Elisabeth Koller, Gerald Wulf, Jan Schleicher, Mark Ringhoffer, Richard Greil, Bernd Hertenstein, Jürgen Krauter, Uwe M Martens, David Nachbaur, Maisun Abu Samra, Sigrid Machherndl-Spandl, Nadezda Basara, Claudia Leis, Anika Schrade, Silke Kapp-Schwoerer, Sibylle Cocciardi, Lars Bullinger, Felicitas Thol, Michael Heuser, Peter Paschka, Verena I Gaidzik, Maral Saadati, Axel Benner, Richard F Schlenk, Konstanze Döhner, Arnold Ganser, Michael W.M. Kühn, Mohammad Wattad, Uwe M. Martens, Verena I. Gaidzik, Richard F. Schlenk
Publikováno v:
The Lancet Haematology.
Autor:
Nawid, Albinger, Rita, Pfeifer, Marcus, Nitsche, Sarah, Mertlitz, Julia, Campe, Katja, Stein, Hermann, Kreyenberg, Ralf, Schubert, Melissa, Quadflieg, Dina, Schneider, Michael W M, Kühn, Olaf, Penack, Congcong, Zhang, Nina, Möker, Evelyn, Ullrich
Publikováno v:
Blood cancer journal. 12(4)
Acute myeloid leukemia (AML) is a malignant disorder derived from neoplastic myeloid progenitor cells characterized by abnormal proliferation and differentiation. Although novel therapeutics have recently been introduced, AML remains a therapeutic ch
Publikováno v:
Current opinion in hematology. 28(5)
Comprehensive sequencing studies aimed at determining the genetic landscape of myeloid neoplasms have identified epigenetic regulators to be among the most commonly mutated genes. Detailed studies have also revealed a number of epigenetic vulnerabili
Autor:
Katrin, Teich, Julia, Krzykalla, Silke, Kapp-Schwoerer, Verena I, Gaidzik, Richard F, Schlenk, Peter, Paschka, Daniela, Weber, Walter, Fiedler, Michael W M, Kühn, Thomas, Schroeder, Karin, Mayer, Michael, Lübbert, Dhanya, Ramachandran, Axel, Benner, Arnold, Ganser, Hartmut, Döhner, Michael, Heuser, Konstanze, Döhner, Felicitas, Thol
Publikováno v:
Haematologica