Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Michael Wördehoff"'
Autor:
Rebecca Sternke‐Hoffmann, Xun Sun, Andreas Menzel, Miriam Dos Santos Pinto, Urte Venclovaite, Michael Wördehoff, Wolfgang Hoyer, Wenwei Zheng, Jinghui Luo
Publikováno v:
Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)
Abstract The coacervation of alpha‐synuclein (αSyn) into cytotoxic oligomers and amyloid fibrils are considered pathological hallmarks of Parkinson's disease. While aggregation is central to amyloid diseases, liquid–liquid phase separation (LLPS
Externí odkaz:
https://doaj.org/article/10bfb530c60d48c099309f9f078216d8
Autor:
Michael Wördehoff, Wolfgang Hoyer
Publikováno v:
Bio-Protocol, Vol 8, Iss 14 (2018)
Studying the aggregation of amyloid proteins like α-synuclein in vitro is a convenient and popular tool to gain kinetic insights into aggregation as well as to study factors (e.g., aggregation inhibitors) that influence it. These aggregation assays
Externí odkaz:
https://doaj.org/article/3f4fa28bc1e5434ba47def9ebff6daac
Autor:
Silke Dornieden, Andreas Müller-Schiffmann, Heinrich Sticht, Nan Jiang, Yeliz Cinar, Michael Wördehoff, Carsten Korth, Susanne Aileen Funke, Dieter Willbold
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59820 (2013)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with devastating effects. Currently, therapeutic options are limited to symptomatic treatment. For more than a decade, research focused on immunotherapy for the causal treatment of
Externí odkaz:
https://doaj.org/article/121dd23d47ec4c12979a8398704700cf