Výsledky vyhledávání - "Michael W, West"

De novo amyloid proteins from designed combinatorial libraries

Autor: James Beasley, Michael H. Hecht, Weixun Wang, Joseph D. Mancias, Michael W. West, Jennifer Patterson

Publikováno v: Proceedings of the National Academy of Sciences. 96:11211-11216

Amyloid deposits are associated with several neurodegenerative diseases, including Alzheimer’s disease and the prion diseases. The amyloid fibrils isolated from these different diseases share similar structural features. However, the protein sequen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00754c7d3ceeb036c924c45065667bb7
https://doi.org/10.1073/pnas.96.20.11211

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Nitric Oxide Inhibition Simulates the Enhancement of α1Agonist-Induced Vasoconstriction in Diabetes

Autor: Stewart P. Wang, Lisa Dresner, Ihor N. Ponomarenko, Richard B. Wait, Cathy M. Mueller, Michael W. West

Publikováno v: Journal of Surgical Research. 70:119-123

We have previously reported that endothelium-dependent, nitric oxide (NO)-mediated vasorelaxation is impaired in diabetic mesenteric arteries. We hypothesized that vasoconstrictor responses should therefore be enhanced. The purpose of this study was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1631c29ff5a904cc143fe9884913a49
https://doi.org/10.1006/jsre.1997.5106

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Effect of short-term pair housing of juvenile rhesus macaques (Macaca mulatta) on immunologic parameters

Autor: Carrie G, Benton, Michael W, West, Shane M, Hall, Shannon T, Marko, Joshua C, Johnson

Publikováno v: Journal of the American Association for Laboratory Animal Science : JAALAS. 52(3)

Social housing of nonhuman primates (NHP) in an infectious disease setting presents unique challenges, and individual housing is often scientifically justified. At our institute, we recognized an opportunity to limit individual housing to the minimal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f2533d39f055b013dea96483f86e2489
https://pubmed.ncbi.nlm.nih.gov/23849405

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Binary patterning of polar and nonpolar amino acids in the sequences and structures of native proteins

Autor: Michael H. Hecht, Michael W. West

Publikováno v: Protein Science. 4:2032-2039

Protein sequences can be represented as binary patterns of polar ([symbol: see text]) and nonpolar ([symbol: see text]) amino acids. These binary sequence patterns are categorized into two classes: Class A patterns match the structural repeat of an i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5608c1ac39b7b60aa0a4151983a2c367
https://doi.org/10.1002/pro.5560041008

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Extensional reactivation of thrust faults accompanied by coseismic surface rupture, southwestern Wyoming and north-central Utah

Autor: Michael W. West

Publikováno v: Geological Society of America Bulletin. 105:1137-1150

Extensional reactivation of thrust faults north of the Uinta Mountains in Utah and Wyoming is accompanied by Quaternary surface faulting, tilting, and monoclinal folding. The 40-km-long Bear River fault zone consists of down-to- the-west, right-stepp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3143e535761b220e03e3bd7edf8bdd3d
https://doi.org/10.1130/0016-7606(1993)105<1137:erotfa>2.3.co

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Alterations in cytokines and effects of dexamethasone immunosuppression during subclinical infections of invasive Klebsiella pneumoniae with hypermucoviscosity phenotype in rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques

Autor: Robin L, Burke, Michael W, West, Rebecca, Erwin-Cohen, Edward B, Selby, Diana E, Fisher, Nancy A, Twenhafel

Publikováno v: Comparative medicine. 60(1)

Invasive Klebsiella pneumoniae with the hypermucoviscosity phenotype (HMV K. pneumoniae) is an emerging human pathogen that also has been attributed to fatal multisystemic disease in African green monkeys at our institution. Combining a cluster of su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ab8d514e7532190d53146c9150cadc48
https://pubmed.ncbi.nlm.nih.gov/20158951

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Effects of diabetes and uremia on mesenteric vascular reactivity

Autor: Richard B. Wait, Dale A. Distant, Michael W. West, Jordan F. Fleishhacker, Cathy M. Mueller, Lisa Dresner, Stewart P. Wang

Publikováno v: Surgery. 120(2)

Diabetes and uremia are comorbid conditions that have significant effects on cardiovascular physiology. These studies were designed to examine the effects of diabetes and uremia on vascular reactivity.Sprague-Dawley rats were divided into control (C)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34789782f4178d4c39ca27cae6315ba
https://pubmed.ncbi.nlm.nih.gov/8751601

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