Zobrazeno 1 - 10
of 3 663
pro vyhledávání: '"Michael W, Weiner"'
Autor:
Kwangsik Nho, Shannon L. Risacher, Liana G. Apostolova, Paula J. Bice, Jared R. Brosch, Rachael Deardorff, Kelley Faber, Martin R. Farlow, Tatiana Foroud, Sujuan Gao, Thea Rosewood, Jun Pyo Kim, Kelly Nudelman, Meichen Yu, Paul Aisen, Reisa Sperling, Basavaraj Hooli, Sergey Shcherbinin, Diana Svaldi, Clifford R. Jack, William J. Jagust, Susan Landau, Aparna Vasanthakumar, Jeffrey F. Waring, Vincent Doré, Simon M. Laws, Colin L. Masters, Tenielle Porter, Christopher C. Rowe, Victor L. Villemagne, Logan Dumitrescu, Timothy J. Hohman, Julia B. Libby, Elizabeth Mormino, Rachel F. Buckley, Keith Johnson, Hyun-Sik Yang, Ronald C. Petersen, Vijay K. Ramanan, Nilüfer Ertekin-Taner, Prashanthi Vemuri, Ann D. Cohen, Kang-Hsien Fan, M. Ilyas Kamboh, Oscar L. Lopez, David A. Bennett, Muhammad Ali, Tammie Benzinger, Carlos Cruchaga, Diana Hobbs, Philip L. De Jager, Masashi Fujita, Vaishnavi Jadhav, Bruce T. Lamb, Andy P. Tsai, Isabel Castanho, Jonathan Mill, Michael W. Weiner, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI), the Department of Defense Alzheimer’s Disease Neuroimaging Initiative (DoD-ADNI), the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study) and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN), the Australian Imaging, Biomarker & Lifestyle Study (AIBL), Andrew J. Saykin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Determining the genetic architecture of Alzheimer’s disease pathologies can enhance mechanistic understanding and inform precision medicine strategies. Here, we perform a genome-wide association study of cortical tau quantified by positron
Externí odkaz:
https://doaj.org/article/534dba93d5bf4620975ce9a0f564baf7
Autor:
Cristina Jaén, Christopher Maute, Scott Mackin, Monica R Camacho, Diana Truran, Rachel Nosheny, Michael W Weiner, Pamela Dalton
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301264 (2024)
BackgroundEarly identification of deficits in our ability to perceive odors is important as many normal (i.e., aging) and pathological (i.e., sinusitis, viral, neurodegeneration) processes can result in diminished olfactory function. To realistically
Externí odkaz:
https://doaj.org/article/58398d384f7344958aa100a2ad5b9e3f
Autor:
Miriam T. Ashford, Chengshi Jin, John Neuhaus, Adam Diaz, Anna Aaronson, Rachana Tank, Joseph Eichenbaum, Monica R. Camacho, Juliet Fockler, Aaron Ulbricht, Derek Flenniken, Diana Truran, Robert Scott Mackin, Michael W. Weiner, Monica Rivera Mindt, Rachel L. Nosheny
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION This study aimed to understand whether older adults’ longitudinal completion of assessments in an online Alzheimer's disease and related dementias (ADRD)–related registry is influenced by self‐reported medical conditions.
Externí odkaz:
https://doaj.org/article/ac8070f83d8a491a8f4a1960fc963b4d
Autor:
Pierrick Bourgeat, Vincent Doré, Christopher C. Rowe, Tammie Benzinger, Duygu Tosun, Manu S. Goyal, Pamela LaMontagne, Liang Jin, Michael W. Weiner, Colin L. Masters, Jurgen Fripp, Victor L. Villemagne, for the Alzheimer's Disease Neuroimaging Initiative, OASIS3, and the AIBL research group
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 3, Pp n/a-n/a (2023)
Abstract INTRODUCTION The Centiloid (CL) project was developed to harmonize the quantification of amyloid beta (Aβ) positron emission tomography (PET) scans to a unified scale. The CL neocortical mask was defined using 11C Pittsburgh compound B (PiB
Externí odkaz:
https://doaj.org/article/5776b4bca24f437f806ac7c5e2774184
Autor:
Rosita Shishegar, Timothy Cox, David Rolls, Pierrick Bourgeat, Vincent Doré, Fiona Lamb, Joanne Robertson, Simon M. Laws, Tenielle Porter, Jurgen Fripp, Duygu Tosun, Paul Maruff, Greg Savage, Christopher C. Rowe, Colin L. Masters, Michael W. Weiner, Victor L. Villemagne, Samantha C. Burnham
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract To improve understanding of Alzheimer’s disease, large observational studies are needed to increase power for more nuanced analyses. Combining data across existing observational studies represents one solution. However, the disparity of su
Externí odkaz:
https://doaj.org/article/42fdcdd7f3cb4cf2a359b106d65ccf69
Autor:
Pierrick Bourgeat, Vincent Doré, Samantha C. Burnham, Tammie Benzinger, Duygu Tosun, Shenpeng Li, Manu Goyal, Pamela LaMontagne, Liang Jin, Christopher C Rowe, Michael W. Weiner, John C Morris, Colin L Masters, Jurgen Fripp, Victor L Villemagne
Publikováno v:
NeuroImage, Vol 262, Iss , Pp 119527- (2022)
Introduction: The Centiloid scale was developed to harmonise the quantification of β-amyloid (Aβ) PET images across tracers, scanners, and processing pipelines. However, several groups have reported differences across tracers and scanners even afte
Externí odkaz:
https://doaj.org/article/128cc763d3534e119f8b75294ba84d3d
Autor:
Matthias Arnold, Kwangsik Nho, Alexandra Kueider-Paisley, Tyler Massaro, Kevin Huynh, Barbara Brauner, Siamak MahmoudianDehkordi, Gregory Louie, M. Arthur Moseley, J. Will Thompson, Lisa St John-Williams, Jessica D. Tenenbaum, Colette Blach, Rui Chang, Roberta D. Brinton, Rebecca Baillie, Xianlin Han, John Q. Trojanowski, Leslie M. Shaw, Ralph Martins, Michael W. Weiner, Eugenia Trushina, Jon B. Toledo, Peter J. Meikle, David A. Bennett, Jan Krumsiek, P. Murali Doraiswamy, Andrew J. Saykin, Rima Kaddurah-Daouk, Gabi Kastenmüller
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Sex and the APOE ε4 genotype are important risk factors for late-onset Alzheimer’s disease. In the current study, the authors investigate how sex and APOE ε4 genotype modify the association between Alzheimer’s disease biomarkers and metabolites
Externí odkaz:
https://doaj.org/article/4622f4afa16f4c509372906b7b40a13c
Autor:
Kelly V. Giudici, Sophie Guyonnet, Christelle Cantet, Philipe deSouto Barreto, Michael W. Weiner, Duygu Tosun, Corina Boschat, Julie Hudry, Sandrine Andrieu, Bruno Vellas, Jeroen A. J. Schmitt, for the Nolan/DSA group
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction This study aimed to test the efficacy of a nutritional blend (NB) in improving nutritional biomarkers and preventing cognitive decline among older adults. Methods A 1‐year randomized, double‐blind, multicenter, placebo‐con
Externí odkaz:
https://doaj.org/article/7f1c2f08bbb54f7ea7ba5c374da4206b
Autor:
Rachel L. Nosheny, Chengshi Jin, John Neuhaus, Philip S. Insel, Robert Scott Mackin, Michael W. Weiner, Alzheimer’s Disease Neuroimaging Initiative investigators
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 12, Pp 2448-2459 (2019)
Abstract Objective Identifying individuals at risk for cognitive decline, Mild Cognitive Impairment (MCI), and dementia due to Alzheimer’s disease (AD) is a critical need. Functional decline is associated with risk and can be efficiently assessed b
Externí odkaz:
https://doaj.org/article/b488f799435b4989ad20ea70afa1304b
Autor:
Yeji Moon, Jin-Ju Yang, Won June Lee, Ji Young Lee, Yu Jeong Kim, Han Woong Lim, The Alzheimer's Disease Neuroimaging Initiative (ADNI), Michael W Weiner, Paul Aisen, Ronald Petersen, Clifford Jack, Matthew Bernstein, Nick Fox, Paul Thompson, Norbert Schuff, Charles DeCArli, Bret Borowski, Jeff Gunter, Matt Senjem, Prashanthi Vemuri, David Jones, Kejal Kantarci, Chad Ward, Laurel Beckett
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Purpose: To quantitatively investigate the microstructural properties of the optic nerve (ON) in vivo using diffusion magnetic resonance imaging (dMRI) tractography in an elderly population and to determine the differences between the ON diffusion pr
Externí odkaz:
https://doaj.org/article/e722e1c62aaa49ed9d2eff4e1b6ed198