Health-related quality of life and utility outcomes with selinexor in relapsed/refractory diffuse large B-cell lymphoma

Autor: Agnes Nagy, Rene-Olivier Casasnovas, Sameer Bakhshi, Sharon Shacham, Juan-Manuel Sancho, Ronit Gurion, Josée M. Zijlstra, Jatin P. Shah, Miklos Egyed, Brian T. Hill, Krzysztof Warzocha, Gabriel Tremblay, Michael W. Schuster, Fritz Offner, Reda Bouabdallah, Dimitrios Tomaras, Paolo Caimi, Andre Goy, Priyanka Samal, Catherine Thieblemont, Joost S.P. Vermaat, Matthew Ku, Ulrich Jäger, John Kuruvilla, Nagesh Kalakonda, George A Follows, Eric Van Den Neste, Miguel Ángel Canales Albendea, Michael Kauffman, Nada Hamad, Fatima De la Cruz, Patrick Daniele, Marie Maerevoet, Theodoros Vasilakopoulos, Federica Cavallo, Sylvain Choquet

Publikováno v: Future Oncology
Future Oncology, Future Medicine, 2021, 17 (11), pp.1295-1310. ⟨10.2217/fon-2020-0946⟩
Future Oncology, 17(11), 1295-1310. FUTURE MEDICINE LTD
FUTURE ONCOLOGY
Future oncology, Vol. 17, no.11, p. 1295-1310 (2021)

Aim: Evaluate health-related quality of life (HRQoL) and health utility impact of single-agent selinexor in heavily pretreated patients with relapsed/refractory diffuse large B-cell lymphoma. Patients & methods: Functional Assessment of Cancer Therap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6489da8e0ec446342a61908102b6dd3
https://doi.org/10.2217/fon-2020-0946

Selinexor in patients with relapsed or refractory diffuse large B-cell lymphoma (SADAL): a single-arm, multinational, multicentre, open-label, phase 2 trial

Autor: Josée M. Zijlstra, Anita Joshi, Marie Maerevoet, Joost S.P. Vermaat, Eric Van Den Neste, Kelly Corona, Fatima De la Cruz, Olivier Casasnovas, Andre Goy, Michael W. Schuster, Reda Bouabdallah, Sourav Mishra, Sharon Shacham, Sameer Bakhshi, George A Follows, Michael Kauffman, Hongwei Wang, Yosef Landesman, Juan-Manuel Sancho, Theodoros P. Vassilakopoulos, Miguel Canales, Federica Cavallo, Jean Richard Saint-Martin, Catherine Thieblemont, Hua Chang, Nada Hamad, Miklos Egyed, Nagesh Kalakonda, Ulrich Jaeger, Ronit Gurion, Fritz Offner, Krzysztof Warzocha, Daniel McCarthy, Xiwen Ma, Sylvain Choquet, Brian T. Hill, Jatin P. Shah

Publikováno v: The Lancet Haematology, 7(7), e511-e522. Lancet Publishing Group
Kalakonda, N, Maerevoet, M, Cavallo, F, Follows, G, Goy, A, Vermaat, J S P, Casasnovas, O, Hamad, N, Zijlstra, J M, Bakhshi, S, Bouabdallah, R, Choquet, S, Gurion, R, Hill, B, Jaeger, U, Sancho, J M, Schuster, M, Thieblemont, C, De la Cruz, F, Egyed, M, Mishra, S, Offner, F, Vassilakopoulos, T P, Warzocha, K, McCarthy, D, Ma, X, Corona, K, Saint-Martin, J R, Chang, H, Landesman, Y, Joshi, A, Wang, H, Shah, J, Shacham, S, Kauffman, M, Van Den Neste, E & Canales, M A 2020, ' Selinexor in patients with relapsed or refractory diffuse large B-cell lymphoma (SADAL) : a single-arm, multinational, multicentre, open-label, phase 2 trial ', The Lancet Haematology, vol. 7, no. 7, pp. e511-e522 . https://doi.org/10.1016/S2352-3026(20)30120-4
Lancet Haematology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname

BACKGROUND: Relapsed or refractory diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer with a median overall survival of less than 6 months. We aimed to assess the response to single-agent selinexor, an oral selective inhibitor of nuclear e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a5caa4328ab8a348c48fb45df0a5c5
https://doi.org/10.1016/s2352-3026(20)30120-4

Frailty is associated with long-term outcome in patients with sepsis who are over 80 years old: results from an observational study in 241 European ICUs

Autor: Nigel White, Jenny Lord, Angela Prado Mira, Ala Khaled, Hubert Hymczak, Kristian Strand, Lenneke E M Haas, Mirosław Czuczwar, Lettie van den Berg, Pieter De Buysscher, Małgorzata Lipińska-Gediga, Simon Dubler, Michel Djibré, Ignacio Martin-Loeches, Georgina Randell, Diederik Gommers, Jose Maia, Patrick Meybohm, Wojciech Gola, Lina De Geer, Tom Lawton, Jonas Juul Pedersen, Isabel Amorim Ferreira, Kristina Fuest, Marcus Franz, McDonald Mupudzi, Kounougeri Aikaterini, Zoi Aidoni, Anastasia Koutsikou, Joakim Sivik, Hans Flaatten, Catia Cilloniz, Paweł Zatorski, Sally Humphreys, Henrik Westberg, Eva Rice, Peter de Jager, Helder Filipe, Stefania Brusa, Maria Faulkner, Jan Stefaniak, Cyril Charron, Nuno Candeias, Sten Walther, Nathalie Rolin, Muhammed Elhadi, Marta Serwa, Sebastian Allgäuer, Thomas Elkmann, Philipp Eller, Jean-Luc Chagnon, Gonzalo Navarro Velasco, Raimund Helbok, Catherine Motherway, Dorota Studzińska, Alan Pope, Ahmed Tarek, Cristina Sousa, Natalia Kozera, Michael Horacek, Camilla Brorsson, Tom Dormans, Nuno Catorze, Michael Joannidis, Andrea Neville Cracchiolo, Walter Swinnen, Oscar Hoiting, Africa Lores, Dominic Spray, Vladislav Belskiy, Marijana Mikačić, Rachel Savine, Tim Rahmel, Christoffer Sølling, Fredrik Schiöler, Henning Ebelt, Urszula Kościuczuk, Marek Pietruszko, Alexander D Cornet, Vasiiios Zidianakis, Bogdan Raitsiou, Ana Rita Santos, Nick Spittle Nick Spittle, Jan Peter Jensen, Alena Breidablik Alena Breidablik, Wojciech Szczeklik, Joerg C. Schefold, Karin Kleiven Thiringer, Alexandre Fernandes Pinto, Antoine Romen, Ingeborg D Welters, Nikolaas de Neve, Joanne Jones, Carole Boulanger, Ciaran Hart, Georgios Papathanakos, Jessica Nauska, Gaspar Eixarch, Pål Klepstad, Wesal Ali Belkhair, Ximena Watson, Brian Marsh, Emmanuel Guerot, Michael W. Schuster, Julie North, Bartosz Kudlinski, Alessandro Morandi, Stefan Schering, Fotios Tsimpoukas, Mercedes Ibarz, Ioannis Koutsodimitropoulos, Maurizio Cecconi, David Perez-Torres, Stephan Steiner, Agnieszka Kubisz-Pudelko, Johan Berkius, Phillipa Wakefield, Joanna Zorska, Anne-Karin Rime, Jacobo Bacariza Blanco, Reni Jacob, Guillaume Besch, Jane Evans, Mathilde Hummelmose Enevoldsen, Jasper Haringman, Xavier Valette, Pierre Garçon, Waldemar Cyrankiewicz, Megan Lea-Hagerty, Jason Cupitt, Yolanda Baird, Eberhard Barth, Stylliani Kourelea, Christine Cramer, Gerardo Aguilar, Christophe Vinsonneau, Maud Mousset Hovaere, Hans Frank Strietzel, Patricia Jimeno Cubero, René Schmutz, Aristide Morigi, Jonathan Ball, Raphael Romano Bruno, Kirsti Tøien, Ahmed Elhadi, Susan Dowling, Antonio Artigas, Aleksandra Biernacka, Clare Bolger, Italo Calamai, Dorthe Ørsnes, Giorgos Marinakis, Amy Collins, Leila Hergafi, Didier Thevenin, Michael Spivey, Bård E S Dahle, Willem Dieperink, Lucie Vettoretti, Vryza Konstantinia, Tasioudis Polychronis, Laura Ortiz-Ruiz De Gordoa, Julien Maizel, Louise Bell, Nicholas Love, Christian Frey, Joanna Solek-Pastuszka, Richard Pugh, Stefan J. Schaller, Hervé Mentec, Mercedes Ibarz Villamayor, Ritoo Kapoor, W. Khaliq, Gemma Gomà, Patrick Morgan, Finn H. Andersen, Madhu Balasubramaniam, Irina Grecu, Filippo Boroli, Saad Nseir, Mariusz Piechota, Ana M. Fernandes, Katarzyna Cwyl, Elli Niki Flioni, Jørund Langørgen, Kiran Salaunkey, Jean-Pierre Quenot, Philippe Burtin, Michael Reay, Ryszard Gawda, Ariane Boumendil, Anders Bastiansen, Hazem Ahmed, Evangelia Neou, Ihor Yovenko, Rik T Gerritsen, Bente Jannestad, Tarkeshwari Mane, Richard Innes, Kelly Tiercelet, Christian Jung, Rui Moreno, Maciej Zukowski, Dariusz Maciejewski, Dylan W. de Lange, Jeremy Henning, Paweł Nasiłowski, Estefania Prol-Silva, Tilemachos Zafeiridis, Lukasz J Krzych, Jérémy Rosman, Tobias Graf, Sonia López-Cuenca, Marcela Vizcaychipi, Jeremy Castaneray, Steve Rose, Vongayi Ogbeide, Arnaud Galbois, Yuriy Nalapko, Sandra Oeyen, Joke Nollet, Ismail Yıldız, Chris Read, Philippe Eckert, Ashok Raj, Anita Slapgard, Anna Kluzik, Mirosław Ziętkiewicz, Christian Rabe, Guillaume Savary, Noemí Llamas Fernández, João Teles Carvalho, Nikoletta Rovina, Jakob Edelberg Thomsen, Britt Sjøbøe, Andreas Husted, Jean-Philippe Rigaud, Bertrand Guidet, Piotr Galkin, Marián Irazábal Jaimes, Anders Sjöqvist, Paweł Sendur, Thorben Dieck, A. Vakalos, Enver Rodriguez, Jesper Fjølner, Eva van Boven, Inês Barros, Susannah Leaver, Patricia Williams, Messika Messika, Emilio Maseda, Michael Hahn, Teresa Tomasa

Publikováno v: Age and Ageing, 50(5), 1719-1727. Baillière Tindall Ltd

Background Sepsis is one of the most frequent reasons for acute intensive care unit (ICU) admission of very old patients and mortality rates are high. However, the impact of pre-existing physical and cognitive function on long-term outcome of ICU pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf27ea6af7250f42401a12219e0e513
https://research.hanze.nl/en/publications/3dead5ac-9170-4ca2-ba3b-3581001bd4c9

Enzymatic-based cytometry, a sensitive single-cell cytometric method to assess BCR-ABL1 activity in CML

Autor: Chiara Luberto, Ling Li, Eric Brouzes, Phenix-Lan Quan, Jinzhu Yu, Sitapriya Moorthi, Michael W. Schuster, Ki Oh, Helmut H. Strey

Publikováno v: Lab Chip

We developed a simple, rapid and cost-effective enzymatic-based cytometry platform to measure intracellular signaling pathway activity. Our single-cell microwell array platform quantifies protein phosphorylation using enzymatic signal amplification a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b9b54ba118cc3dd0183b49d0045d36
https://doi.org/10.1039/c9lc01213c

Illness Uncertainties Tied to Developmental Tasks Among Young Adult Survivors of Hematologic Cancers

Autor: Amanda M. Marin-Chollom, Michael W. Schuster, Tracey A. Revenson, Joel Erblich, Ian Z Pervil, Aliza A. Panjwani, Lisa R. Rubin

Publikováno v: Journal of Adolescent and Young Adult Oncology. 8:149-156

Young adulthood is a period of building autonomy, relationships, and careers. Experiencing cancer as a young adult (YA) is an "off-time" event in the normative adult life cycle and may interrupt age-specific goals. The majority of prior research on i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed53bd72940e35970bdb13852392563
https://doi.org/10.1089/jayao.2018.0024