Origanum majorana L. protects against neuroinflammation-mediated cognitive impairment: a phyto-pharmacological study

Autor: Reham Wagdy, Reham M. Abdel-Kader, Ahmed H. El-Khatib, Michael W. Linscheid, Heba Handoussa, Nabila Hamdi

Publikováno v: BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-13 (2023)

Abstract Background Neuroinflammation and oxidative stress are critical players in the pathogenesis of numerous neurodegenerative diseases, such as Alzheimer’s disease (AD) which is responsible for most cases of dementia in the elderly. With the la

Externí odkaz: https://doaj.org/article/a99de4fdfb674488801b311fcb953917

Polyphenols LC-MS2 profile of Ajwa date fruit (Phoenix dactylifera L.) and their microemulsion: Potential impact on hepatic fibrosis

Autor: Khaled A. Nematallah, Nahla A. Ayoub, Essam Abdelsattar, Meselhy R. Meselhy, Mohey M. Elmazar, Ahmed H. El-Khatib, Michael W. Linscheid, Rania M. Hathout, Kavitha Godugu, Aya Adel, Shaker A. Mousa

Publikováno v: Journal of Functional Foods, Vol 49, Iss , Pp 401-411 (2018)

Ajwa fruits are among the most nutritious and economically valuable fruits. In this study, the effect of different solvents on the extraction of polyphenols was investigated. Aqueous acetone (50%) extract contained the highest content of polyphenols

Externí odkaz: https://doaj.org/article/e0f00ab4fbfc46c3a078e2b769d9da2f

Identification of phenolic secondary metabolites from Schotia brachypetala Sond. (Fabaceae) and demonstration of their antioxidant activities in Caenorhabditis elegans

Autor: Mansour Sobeh, Esraa ElHawary, Herbenya Peixoto, Rola M. Labib, Heba Handoussa, Noha Swilam, Ahmed H. El-Khatib, Farukh Sharapov, Tamer Mohamed, Sonja Krstin, Michael W. Linscheid, Abdel Nasser Singab, Michael Wink, Nahla Ayoub

Publikováno v: PeerJ, Vol 4, p e2404 (2016)

Background Schotia brachypetala Sond. (Fabaceae) is an endemic tree of Southern Africa whose phytochemistry and pharmacology were slightly studied. The present work aimed at profiling the major phenolics compounds present in the hydro-alcohol extract

Externí odkaz: https://doaj.org/article/9e191d45c1e94167b5916c54b12f3504

VUV Photodissociation Induced by a Deuterium Lamp in an Ion Trap

Autor: Jens Riedel, Michael W. Linscheid, Stefanie Ickert, Sebastian Beck

Publikováno v: Journal of the American Society for Mass Spectrometry. 30:2114-2122

Tandem mass spectrometry represents an important analytical tool to unravel molecular structures and to study the gas-phase behavior of organic molecules. Besides commonly used methods like collision-induced dissociation and electron capture or trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e5697cf9c66a43b6423e8dd6e27be9
https://doi.org/10.1007/s13361-019-02282-8

Characterization of hepatoprotective metabolites from Artemisia annua and Cleome droserifolia using HPLC/PDA/ESI/MS–MS

Autor: Hesham I. El-Askary, Amira Abdel Motaal, Abdulrhman Alsayari, Ahmed H. El-Khatib, Heba Handoussa, Michael W. Linscheid, Farid A. Badria

Publikováno v: Revista Brasileira de Farmacognosia, Volume: 29, Issue: 2, Pages: 213-220, Published: 27 MAY 2019
Revista Brasileira de Farmacognosia, Vol 29, Iss 2, Pp 213-220 (2019)
Revista Brasileira de Farmacognosia v.29 n.2 2019
Revista Brasileira de Farmacognosia
Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA

The hepatoprotective activities of two traditionally used plants, Cleome droserifolia (Forssk.) Delile, Cleomaceae, and Artemisia annua L., Asteraceae, were recently reported. However, the biologically active metabolites responsible for this activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce59b2ead3492eb7fd3f8d33899b6d28
https://doi.org/10.1016/j.bjp.2018.10.001