Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Michael Voronkov"'
Autor:
Mihai Cernea, Georgiy Nikonov, Janna Ataiants, Cristina Ştefănuţ, John Abernethy, Michael Voronkov
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 866 (2024)
Developing an effective antidote for fentanyl-induced overdose to achieve timely reversal is an unmet public health need. Previously, we found that naloxone derivative NX90 with mild κ-opioid agonistic properties was three-fold more effective than t
Externí odkaz:
https://doaj.org/article/49b8a1bad02c41ab9a00f1b8d709a406
Autor:
Yuki Kikuchi, Eriko Sugano, Shiori Yuki, Kitako Tabata, Yuka Endo, Yuya Takita, Reina Onoguchi, Taku Ozaki, Tomokazu Fukuda, Yoshihiro Takai, Takahiro Kurose, Koichi Tanaka, Yoichi Honma, Eduardo Perez, Maxwell Stock, José R. Fernández, Masanori Tamura, Michael Voronkov, Jeffry B. Stock, Hiroshi Tomita
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8802 (2022)
Age-related macular degeneration is a progressive retinal disease that is associated with factors such as oxidative stress and inflammation. In this study, we evaluated the protective effects of SIG-1451, a non-steroidal anti-inflammatory compound de
Externí odkaz:
https://doaj.org/article/ab3e2b4ec5064c70809809faf75448a0
Autor:
José R. Fernández, Karl Rouzard, Corey Fitzgerald, Jason Healy, Masanori Tamura, Michael Voronkov, Jeffry B. Stock, Maxwell Stock, Eduardo Pérez
Publikováno v:
Cosmetics, Vol 8, Iss 4, p 110 (2021)
Over the past 15 years, small molecule isoprenylcysteine (IPC) analogs have been identified as a potential new class of topical anti-inflammatories. Clinical studies have demonstrated that IPCs are both safe and effective in promoting healthy skin wh
Externí odkaz:
https://doaj.org/article/c13a1b61ae7944d3bfa5402fd9bc6d17
Autor:
Kesava Asam, Agnieszka Staniszewski, Hong Zhang, Scott L Melideo, Adolfo Mazzeo, Michael Voronkov, Kristen L Huber, Eduardo Pérez, Maxwell Stock, Jeffry B Stock, Ottavio Arancio, Russell E Nicholls
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189413 (2017)
Soluble forms of oligomeric beta-amyloid (Aβ) are thought to play a central role in Alzheimer's disease (AD). Transgenic manipulation of methylation of the serine/threonine protein phosphatase, PP2A, was recently shown to alter the sensitivity of mi
Externí odkaz:
https://doaj.org/article/4945a53009bb4b04a6a1a25408a1a5e6
Autor:
Eduardo Pérez, José R. Fernández, Corey Fitzgerald, Karl Rouzard, Jason Healy, Masanori Tamura, Michael Voronkov, Jeffry B. Stock, Maxwell Stock
Publikováno v:
Journal of Cosmetic Dermatology.
Autor:
Yuki Kikuchi, Eriko Sugano, Shiori Yuki, Kitako Tabata, Yuka Endo, Yuya Takita, Reina Onoguchi, Taku Ozaki, Tomokazu Fukuda, Yoshihiro Takai, Takahiro Kurose, Koichi Tanaka, Yoichi Honma, Eduardo Perez, Maxwell Stock, Jose Fernandez, Masanori Tamura, Michael Voronkov, Jeffry B Stock, Hiroshi Tomita
Age-related macular degeneration is a progressive retinal disease that is associated with factors such as oxidative stress, decreased phagocytic activity, and inflammation. In this study, we evaluated the protective effects of SIG-1451, a non-steroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0e1d1c248d219930c2a4f82af5e830
Autor:
Kristen L. Huber, Maxwell Stock, C. Webb, Eduardo Perez, J. Healy, Michael Voronkov, Karl Rouzard, Masanori Tamura, José R. Fernández, Jeffry B. Stock
Publikováno v:
Journal of Cosmetic Dermatology. 19:2386-2393
Background Chia seeds have gained importance as it is the highest known plant source of omega-3 (ω3) polyunsaturated fatty acids. Specifically, chia seeds possess ω3 α-linolenic acid (ALA) and ω6 linoleic acid (LA), together known as Vitamin F, w
Autor:
C. Webb, Jeffry B. Stock, Joel S. Gordon, Maxwell Stock, Kristen L. Huber, Wendi Armbrister, José R. Fernández, Michael Voronkov, Eduardo Perez, J. Healy, Karl Rouzard, Masanori Tamura
Publikováno v:
Journal of Cosmetic Dermatology. 18:1366-1371
Background SIG-1273 is a novel cosmetic active that provides a broad spectrum of benefits to the skin. Considering the chronic skin exposure to pollution in urban areas, we sought to determine if SIG-1273 could provide additional protection against s
Autor:
Cristina Stefanut, M. Cernea, Levon Isakulyan, Georgiy Nikonov, Michael Voronkov, Janna Ataiants, John Abernethy
Publikováno v:
International Journal of Pharmaceutics. 611:121326
Developing an effective antidote for fentanyl-induced overdose (OD) is an unmet medical need that requires both lipophilicity comparable to fentanyl and fast onset of overdose reversal. We synthesized and evaluated a bioreversible derivative of nalox
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 159
Developing non-addictive and safer opioids for pain management is unmet medical need. Among a number of bioreversible derivatives of Nalbuphine - an equipotent to morphine opioid without serious side effects - NB-33 was identified in silico and confi