Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Michael Valenzuela"'
Autor:
Michael Valenzuela, T. Duncan, A. Abey, A. Johnson, C. Boulamatsis, M. A. Dalton, E. Jacobson, L. Brunel, G. Child, D. Simpson, M. Buckland, A. Lowe, J. Siette, F. Westbrook, P. McGreevy
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-20 (2022)
Abstract Background Older companion dogs naturally develop a dementia-like syndrome with biological, clinical and therapeutic similarities to Alzheimer disease (AD). Given there has been no new safe, clinically effective and widely accessible treatme
Externí odkaz:
https://doaj.org/article/181898ebad40466cb6118d9beda2119c
Autor:
David Bartrés‐Faz, Eider Arenaza‐Urquijo, Michael Ewers, Sylvie Belleville, Gaël Chételat, Nicolai Franzmeier, Julie Gonneaud, José María González deEchevarri, Ozioma Okonkwo, Stephanie Schultz, Michael Valenzuela, Yaakov Stern, Prashanthi Vemuri
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Reserve, resilience, maintenance, and related concepts are intensely debated in aging and Alzheimer's disease research. Methods Through a short survey, we gathered information about theoretical concepts and methodologies used am
Externí odkaz:
https://doaj.org/article/1cda8e7bec514d809c19e58eb5de4d42
Autor:
Thomas Duncan, Aileen Lowe, Kuldip Sidhu, Perminder Sachdev, Trevor Lewis, Ruby C.Y. Lin, Vladimir Sytnyk, Michael Valenzuela
Publikováno v:
Stem Cell Reports, Vol 9, Iss 2, Pp 557-570 (2017)
Summary: Repopulation of brain circuits by neural precursors is a potential therapeutic strategy for neurodegenerative disorders; however, choice of cell is critical. Previously, we introduced a two-step culture system that generates a high yield of
Externí odkaz:
https://doaj.org/article/634e79dec56e4e28b3de8f7af2cbe46d
Autor:
Thomas Duncan, Michael Valenzuela
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-9 (2017)
Abstract Alzheimer’s disease (AD) represents arguably the most significant social, economic, and medical crisis of our time. Characterized by progressive neurodegenerative pathology, AD is first and foremost a condition of neuronal and synaptic los
Externí odkaz:
https://doaj.org/article/ba826abc5a9f456fb9183897a33fb9e1
Autor:
Barbara Toson, Daina L Sturnieks, Jasmine Menant, Michael Valenzuela, Robert D Herbert, Kathryn Broadhouse, Stephen R Lord, Daina Sturnieks, Stephen Lord, Rob Herbert, Cameron Hicks, Mayna Ratanapongleka, Natassia Smith, Carly Chaplin, Bethany Halmy, Angeliki Stivactas, Ashley Woodbury, Dinaz Parekh, Matthew Hand, Isabella Hoi Kei leung, Polly Barr, Jennifer Davis
Publikováno v:
BMJ Open, Vol 9, Iss 8 (2019)
BackgroundPhysical and cognitive impairments are important risk factors for falls in older people. However, no studies have been adequately powered to examine whether cognitive or cognitive-motor training can prevent falls in older people. This is de
Externí odkaz:
https://doaj.org/article/99d7edc5b78346679775329f95e55055
Publikováno v:
Frontiers in Human Neuroscience, Vol 10 (2016)
Objective: To quantitatively aggregate effects of cognitive training (CT) on cognitive and functional outcome measures in patients with traumatic brain injury (TBI) more than 12-months post-injury.Design: We systematically searched six databases for
Externí odkaz:
https://doaj.org/article/13ab2f54a9fe4fc1b819fbc35a003bd5
Publikováno v:
PLoS Medicine, Vol 11, Iss 11, p e1001756 (2014)
BackgroundNew effective interventions to attenuate age-related cognitive decline are a global priority. Computerized cognitive training (CCT) is believed to be safe and can be inexpensive, but neither its efficacy in enhancing cognitive performance i
Externí odkaz:
https://doaj.org/article/5f0839db204b4af391a8df609e410457
Autor:
Paul D McGreevy, Dana Georgevsky, Johanna Carrasco, Michael Valenzuela, Deborah L Duffy, James A Serpell
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80529 (2013)
Dogs offer unique opportunities to study correlations between morphology and behavior because skull shapes and body shape are so diverse among breeds. Several studies have shown relationships between canine cephalic index (CI: the ratio of skull widt
Externí odkaz:
https://doaj.org/article/3dedfa35962c44d1a3b1d0bdc6afed52
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59982 (2013)
BACKGROUND: Cognitive training (CT) is effective at improving cognitive outcomes in children with and without clinical impairment as well as older individuals. Yet whether CT is of any preventative health benefit to working age adults is controversia
Externí odkaz:
https://doaj.org/article/b71c700e932641539d68aa883806f8d8
Autor:
Nicole A Kochan, Michael Valenzuela, Melissa J Slavin, Stacey McCraw, Perminder S Sachdev, Michael Breakspear
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23960 (2011)
BackgroundThe capacity of visual working memory (WM) is substantially limited and only a fraction of what we see is maintained as a temporary trace. The process of binding visual features has been proposed as an adaptive means of minimising informati
Externí odkaz:
https://doaj.org/article/058631b894a340cba629f83672f9008f