Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Michael V. Tullius"'
Autor:
Michael V. Tullius, Richard A. Bowen, Peter S. Back, Saša Masleša-Galić, Susana Nava, Marcus A. Horwitz
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTMelioidosis, caused by the intracellular bacterial pathogen and Tier 1 select agent Burkholderia pseudomallei (Bp), is a highly fatal disease endemic in tropical areas. No licensed vaccine against melioidosis exists. In preclinical vaccine st
Externí odkaz:
https://doaj.org/article/f68583f2360041059761a3bd664124bc
Autor:
Cameron R Cunningham, Ameya Champhekar, Michael V Tullius, Barbara Jane Dillon, Anjie Zhen, Justin Rafael de la Fuente, Jonathan Herskovitz, Heidi Elsaesser, Laura M Snell, Elizabeth B Wilson, Juan Carlos de la Torre, Scott G Kitchen, Marcus A Horwitz, Steven J Bensinger, Stephen T Smale, David G Brooks
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005356 (2016)
Persistent viral infections are simultaneously associated with chronic inflammation and highly potent immunosuppressive programs mediated by IL-10 and PDL1 that attenuate antiviral T cell responses. Inhibiting these suppressive signals enhances T cel
Externí odkaz:
https://doaj.org/article/6cc1d512b71d4350b891aaacda9d2b44
Autor:
Marcus A. Horwitz, Chia-Jung Yu, Jeffrey I. Zink, Michael V. Tullius, Sheba Plamthottam, Zilu Li, Bai-Yu Lee, Barbara Jane Dillon, Ruining Wang, Daniel L. Clemens
Publikováno v:
ACS Infectious Diseases. 5:281-291
Francisella tularensis causes a serious and often fatal infection, tularemia. We compared the efficacy of moxifloxacin formulated as free drug vs disulfide snap-top mesoporous silica nanoparticles (MSNs) in a mouse model of pneumonic tularemia. We fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80d798ac8387b353537841d8d7ba7c0
https://doi.org/10.1021/acsinfecdis.8b00268
https://doi.org/10.1021/acsinfecdis.8b00268
Publikováno v:
Infection and Immunity. 87
Mycobacterium tuberculosis, one of the world's leading causes of death, must acquire nutrients, such as iron, from the host to multiply and cause disease. Iron is an essential metal and M. tuberculosis possesses two different systems to acquire iron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec8b2c707617a4655e69bb75b203e73f
https://doi.org/10.1128/iai.00540-18
https://doi.org/10.1128/iai.00540-18
Autor:
Wenxi Xu, Laura M. Snell, Mengdi Guo, Giselle Boukhaled, Bethany L. Macleod, Ming Li, Michael V. Tullius, Cynthia J. Guidos, Ming-Sound Tsao, Maziar Divangahi, Marcus A. Horwitz, Jun Liu, David G. Brooks
Publikováno v:
The Journal of Immunology. 206:62.08-62.08
Chronic viral infections increase severity of Mycobacterium tuberculosis (Mtb) coinfection, yet how they alter the pulmonary microenvironment to foster coinfection and worsen disease severity is unclear. We developed a coinfection model in mice with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::936af5fe858c8a05568e867236fa6ab7
https://doi.org/10.4049/jimmunol.206.supp.62.08
https://doi.org/10.4049/jimmunol.206.supp.62.08
Autor:
Bethany L. MacLeod, Michael V. Tullius, Ming-Sound Tsao, Jun Liu, W. Xu, Ming Li, Maziar Divangahi, Giselle M. Boukhaled, David G. Brooks, Laura M. Snell, Mengdi Guo, Marcus A. Horwitz, Cynthia J. Guidos
Publikováno v:
Immunity
Summary Chronic viral infections increase severity of Mycobacterium tuberculosis (Mtb) coinfection. Here, we examined how chronic viral infections alter the pulmonary microenvironment to foster coinfection and worsen disease severity. We developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e5eb538152f1934178db00f08f19ba
https://doi.org/10.1016/j.immuni.2021.01.003
https://doi.org/10.1016/j.immuni.2021.01.003
Publikováno v:
Infection and immunity. 87(2)
Mycobacterium tuberculosis, one of the world’s leading causes of death, must acquire nutrients, such as iron, from the host to multiply and cause disease. Iron is an essential metal and M. tuberculosis possesses two different systems to acquire iro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a2eb9d9953bafb6054e45e7f4aab9a2
https://pubmed.ncbi.nlm.nih.gov/30455201
https://pubmed.ncbi.nlm.nih.gov/30455201
Publikováno v:
Infection and Immunity. 82:3900-3909
Leprosy remains a major global health problem and typically occurs in regions in which tuberculosis is endemic. Vaccines are needed that protect against both infections and do so better than the suboptimal Mycobacterium bovis BCG vaccine. Here, we ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6220b871c90b3640549bf7b62a2225
https://doi.org/10.1128/iai.01499-13
https://doi.org/10.1128/iai.01499-13
Autor:
Heidi Contreras, Neda Bionghi, Lisa M. McMath, James A. J. Fitzpatrick, Michael V. Tullius, Jacqueline M. Kimmey, Marcus A. Horwitz, Matthew S. Joens, Celia W. Goulding, Vincent P. Le
Publikováno v:
Journal of Biological Chemistry. 289:18279-18289
Mycobacterium tuberculosis has evolved various mechanisms by which the bacterium can maintain homeostasis under numerous environmental assaults generated by the host immune response. M. tuberculosis harbors enzymes involved in the oxidative stress re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f2ef2a852dd7b56f275a15c7e55062
https://doi.org/10.1074/jbc.m114.570119
https://doi.org/10.1074/jbc.m114.570119
Autor:
Ameya Champhekar, Michael V. Tullius, Scott G. Kitchen, Elizabeth B. Wilson, Anjie Zhen, Marcus A. Horwitz, Laura M. Snell, David G. Brooks, Jonathan Herskovitz, Cameron R. Cunningham, Juan Carlos de la Torre, Steven J. Bensinger, Barbara Jane Dillon, Stephen T. Smale, Heidi Elsaesser, Justin Rafael de la Fuente
Publikováno v:
PLoS pathogens, vol 12, iss 1
PLoS Pathogens, Vol 12, Iss 1, p e1005356 (2016)
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 1, p e1005356 (2016)
PLoS Pathogens
Persistent viral infections are simultaneously associated with chronic inflammation and highly potent immunosuppressive programs mediated by IL-10 and PDL1 that attenuate antiviral T cell responses. Inhibiting these suppressive signals enhances T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd235fbab089e62ec3fc38c4cb0c5d4
https://escholarship.org/uc/item/5094109c
https://escholarship.org/uc/item/5094109c
