Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Michael V. Sefton"'
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
Islet transplantation is a promising treatment for type I diabetes (T1D). Despite the high loss of islets during transplantation, current islet transplant protocols continue to rely on portal vein infusion and intrahepatic engraftment. Because of the
Externí odkaz:
https://doaj.org/article/fece0d8a39a14871aba0e8d7ddb947eb
Autor:
Sibel Naska, Scott A. Yuzwa, Adam P.W. Johnston, Smitha Paul, Kristen M. Smith, Maryline Paris, Michael V. Sefton, Alessandro Datti, Freda D. Miller, David R. Kaplan
Publikováno v:
Stem Cell Reports, Vol 6, Iss 1, Pp 74-84 (2016)
Here, we asked whether we could identify pharmacological agents that enhance endogenous stem cell function to promote skin repair, focusing on skin-derived precursors (SKPs), a dermal precursor cell population. Libraries of compounds already used in
Externí odkaz:
https://doaj.org/article/4cd59b2569bd494892c8e39f93f2704b
Autor:
Shahab Lahooti, Michael V. Sefton
Publikováno v:
Cell Transplantation, Vol 9 (2000)
To achieve immunoisolation, mouse L929 fibroblasts were encapsulated in ~400 μm poly(hydroxyethyl methacrylate-co-methyl methacrylate) (HEMA-MMA) microcapsules and were subsequently implanted in the peritoneal cavity of syngeneic C3H mice. As a base
Externí odkaz:
https://doaj.org/article/73aa64cb879840b8ab9ddc4cc455d29b
Autor:
Hasan Uludag, Michael V. Sefton
Publikováno v:
Cell Transplantation, Vol 2 (1993)
To better understand encapsulated cell behaviour, Chinese Hamster Ovary (CHO) fibroblasts were encapsulated in HEMA-MMA microcapsules and short-term (
Externí odkaz:
https://doaj.org/article/722362274135438380cc247538a74eca
Publikováno v:
Regenerative Engineering and Translational Medicine. 9:4-21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e38de3245823023027b8328cc979d97
https://doi.org/10.1007/s40883-022-00263-0
https://doi.org/10.1007/s40883-022-00263-0
Autor:
Michael V. Sefton, Craig A. Simmons
Publikováno v:
Science
Helical alignments within the heart’s musculature have been speculated to be important in achieving physiological pumping efficiencies. Testing this possibility is difficult, however, because it is challenging to reproduce the fine spatial features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9652aadb8dea40e7f9f1ffe18a8ab83
https://pubmed.ncbi.nlm.nih.gov/35857545
https://pubmed.ncbi.nlm.nih.gov/35857545
Autor:
Michael V. Sefton, Miranda M. Carleton
Publikováno v:
Journal of Biomedical Materials Research Part A. 109:2720-2739
Skeletal muscles normally have a remarkable ability to repair themselves; however, large muscle injuries and several myopathies diminish this ability leading to permanent loss of function. No clinical therapy yet exists that reliably restores muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec66c8f03445d3169a7f43b88b129b7
https://doi.org/10.1002/jbm.a.37239
https://doi.org/10.1002/jbm.a.37239
Methacrylic acid-based biomaterials promote peripheral innervation in the subcutaneous space of mice
Autor:
Alaura M. Androschuk, Theresa H. Tam, Redouan Mahou, Cheun Lo, Michael W. Salter, Michael V. Sefton
Peripheral nerve innervation is essential for regulating tissue repair and regeneration. MAA-based biomaterials have been previously shown to promote angiogenesis. Here we show a new role for MAA-based biomaterials in promoting terminal axon nerve gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7b70f628bc31cc0883b585ee0fcab9
https://doi.org/10.1101/2022.04.03.486876
https://doi.org/10.1101/2022.04.03.486876
Publikováno v:
ACS Biomaterials Science & Engineering. 6:6368-6377
Impaired blood vessel formation limits the healing of diabetic ulcers and leaves patients at high risk for amputation. Nonbiologic vascular regenerative materials made of methacrylic acid (MAA) copolymer, such as MAA-co-methyl methacrylate beads, hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc484452343152f12f4ad41e0299e091
https://doi.org/10.1021/acsbiomaterials.0c01222
https://doi.org/10.1021/acsbiomaterials.0c01222
Publikováno v:
Tissue Engineering Part A. 25:911-923
Macrophages play a central role in the host response to tissue engineered constructs and their resultant vascularization. With a diversity of phenotypes, it is important to control the macrophage r...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ebdd9cbf8e83de8d7585f246f10a6b
https://doi.org/10.1089/ten.tea.2018.0222
https://doi.org/10.1089/ten.tea.2018.0222