Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Michael V Accardi"'
Autor:
John C Trefry, Franco D Rossi, Michael V Accardi, Brandi L Dorsey, Thomas R Sprague, Suzanne E Wollen-Roberts, Joshua D Shamblin, Adrienne E Kimmel, Pamela J Glass, Lynn J Miller, Crystal W Burke, Anthony P Cardile, Darci R Smith, Sina Bavari, Simon Authier, William D Pratt, Margaret L Pitt, Farooq Nasar
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009424 (2021)
Most alphaviruses are mosquito-borne and can cause severe disease in humans and domesticated animals. In North America, eastern equine encephalitis virus (EEEV) is an important human pathogen with case fatality rates of 30-90%. Currently, there are n
Externí odkaz:
https://doaj.org/article/c6d1539e38da43f78f4e7ec443930c9c
Publikováno v:
International journal of toxicology. 40(5)
A broad spectrum of chemical entities have been associated with drug-induced seizure (DIS), emphasizing the importance of this potential liability across various drug classes (e.g., antidepressants, antipsychotics, antibiotics, and analgesics among o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e08b38968585fea1c8ad326ba363fac
https://pubmed.ncbi.nlm.nih.gov/34514888
https://pubmed.ncbi.nlm.nih.gov/34514888
Autor:
Crystal W. Burke, Simon Authier, Farooq Nasar, Adrienne E. Kimmel, Joshua D. Shamblin, Pamela J. Glass, Michael V. Accardi, Darci R. Smith, Brandi L. Dorsey, Suzanne E. Wollen-Roberts, Sina Bavari, William D. Pratt, Lynn J. Miller, Margaret L. Pitt, John C. Trefry, Thomas R. Sprague, Franco Rossi, Anthony P. Cardile
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009424 (2021)
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009424 (2021)
Most alphaviruses are mosquito-borne and can cause severe disease in humans and domesticated animals. In North America, eastern equine encephalitis virus (EEEV) is an important human pathogen with case fatality rates of 30–90%. Currently, there are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa2833f649cd281c12307780df40367
http://europepmc.org/articles/PMC8259972
http://europepmc.org/articles/PMC8259972
Autor:
William D. Pratt, Anthony P. Cardile, John C. Trefry, Franco Rossi, Adrienne E. Kimmel, Michael V. Accardi, Lynn Miller, Suzanne E. Wollen-Roberts, Simon Authier, Farooq Nasar, Joshua D. Shamblin, Brandi L. Dorsey, Sina Bavari, Pamela J. Glass, Margaret L. Pitt, Thomas R. Sprague, Darci R. Smith
Most alphaviruses are mosquito-borne and can cause severe disease in humans and domesticated animals. In North America, eastern equine encephalitis virus (EEEV) is an important human pathogen with case fatality rates of 30-90%. Currently, there are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7de0ac86c16e3bf05cc7ad5a12fe2624
https://doi.org/10.1101/2020.12.21.423826
https://doi.org/10.1101/2020.12.21.423826
Autor:
Audrey Sanfacon, Emmanuel Boulay, Ariane Menard, Eric Troncy, Hai Huang, Loïs S. Miraucourt, Michael K. Pugsley, Anne-Marie Downey, Mireille Guerrier, Michael V. Accardi, Wendy Tan, Simon Authier, Michelle Dubuc-Mageau
Publikováno v:
International journal of toxicology. 39(6)
Introduction: Corrected QT (QTc) interval is an essential proarrhythmic risk biomarker, but recent data have identified limitations to its use. The J to T-peak (JTp) interval is an alternative biomarker for evaluating drug-induced proarrhythmic risk.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3398e1cf1e8cfd89a6f00ce54b33011f
https://pubmed.ncbi.nlm.nih.gov/33063577
https://pubmed.ncbi.nlm.nih.gov/33063577
Seizure liability assessments using the hippocampal tissue slice: Comparison of non-clinical species
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 93:59-68
Introduction Traditionally, rat hippocampal tissue slice models are used as an in vitro electrophysiology assay to assess seizurogenic potential in early drug development despite non-clinical species-specific differences noted during in vivo seizure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d56a4f2ecb18dc1c200fdb55efe576b
https://doi.org/10.1016/j.vascn.2017.11.003
https://doi.org/10.1016/j.vascn.2017.11.003
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 111:107012
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8f9fe39eaf083c656418ac9c9ffe0fb
https://doi.org/10.1016/j.vascn.2021.107012
https://doi.org/10.1016/j.vascn.2021.107012
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 111:106975
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c66f92f5d58ac45e2cd3e67fb2f3f78
https://doi.org/10.1016/j.vascn.2021.106975
https://doi.org/10.1016/j.vascn.2021.106975
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 111:106981
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ffc0f53c69fc6424435c974120c1f56
https://doi.org/10.1016/j.vascn.2021.106981
https://doi.org/10.1016/j.vascn.2021.106981
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 111:106972
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5a1fef7f2af2a15f5035f036cbd864f
https://doi.org/10.1016/j.vascn.2021.106972
https://doi.org/10.1016/j.vascn.2021.106972