Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Michael U. Martin"'
Autor:
Niamh Corduff, MBBS, FRACS, Je-Young Park, MD, Pacifico E. Calderon, MD, MBEth, MEd, Hosung Choi, MD, Mary Dingley, MBBS, FACCSM, FCPCA, Wilson W. S. Ho, MBChB, FRCSEd, Michael U. Martin, PhD, Lis S. Suseno, MD, Fang-Wen Tseng, MD, Vasanop Vachiramon, MD, Rungsima Wanitphakdeedecha, MD, MA, MSc, Jonathan N. T. Yu, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss 6, p e5892 (2024)
Background:. As long-term, regular aesthetic botulinum neurotoxin A (BoNT-A) use becomes more commonplace, it is vital to understand real-world risk factors and impact of BoNT-A immunoresistance. The first Aesthetic Council on Ethical Use of Neurotox
Externí odkaz:
https://doaj.org/article/be2c0341340d465c9548fd917449176c
Autor:
Wilson W. S. Ho, Lisa Chan, Niamh Corduff, Wang-Tak Lau, Michael U. Martin, Clifton Ming Tay, Sandy Wang, Raymond Wu
Publikováno v:
Toxins, Vol 15, Iss 7, p 456 (2023)
With increasing off-label aesthetic indications using higher botulinum neurotoxin A (BoNT-A) doses and individuals starting treatment at a younger age, particularly in Asia, there is a greater risk of developing immunoresistance to BoNT-A. This warra
Externí odkaz:
https://doaj.org/article/1d7bfe7b12254036bc48fb9971ad1108
Autor:
Wilson W. S. Ho, MBChB, FRCSEd, Philipp Albrecht, MD, Pacifico E. Calderon, MD, MBEth, Niamh Corduff, MBBS, FRACS, David Loh, MBBS, Michael U. Martin, PhD, Je-Young Park, MD, Lis S. Suseno, MD, Fang-Wen Tseng, MD, Vasanop Vachiramon, MD, Rungsima Wanitphakdeedecha, MD, MA, MSc, Chong-Hyun Won, MD, PhD, Jonathan N. T. Yu, MD, Mary Dingley, MBBS, FACCSM, FCPCA
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 10, Iss 6, p e4407 (2022)
Background:. Botulinum neurotoxin A (BoNT-A) injection is the most widely performed aesthetic procedure and a first-line therapeutic option for various medical conditions. The potential for BoNT-A immunoresistance and secondary nonresponse related to
Externí odkaz:
https://doaj.org/article/d3d0a0c0a8e34491a526fb886264d38c
Publikováno v:
Nature immunology. 20(9)
Therapeutic efficacy in inflammatory diseases is hampered by disease complexity. A monoclonal antibody that neutralizes IL-1R3, the common co-receptor of most inflammatory IL-1 cytokines, opens up new perspectives in effective disease management.
Autor:
Michael U. Martin
Publikováno v:
Seminars in Immunology. 25:449-457
Interleukin-33 (IL-33) is an unconventional member of the IL-1 family: it is a dual function cytokine. Many different cell types, tissue cells and leukocytes, produce IL-33 either constitutively or after stimulation and release it by a poorly defined
Autor:
Anna M. Möbus, Jan Grimmel, Shafaqat Ali, Sybelle Goedicke, Michael U. Martin, Ralf Ross, Ana-Maria Bulau, Philip Bufler
Publikováno v:
Journal of Immunological Methods. 387:219-227
The dual function cytokines IL-1α, IL-33 and IL-37 are members of the IL-1 cytokine family. Besides of being able to bind to their cognate receptors on target cells, they can act intracellularly in the producing cell. All three are able to transloca
Autor:
Tanja Schmudlach, Christian Krettek, Stefan Baus, Frank Hildebrand, Konstantinos Raymondos, Christian Weilbach, Michael Frink, Tobias Welte, Michael U. Martin
Publikováno v:
Injury. 43:189-195
Alveolar IL-8 has been reported to early identify patients at-risk to develop ARDS. However, it remains unknown how alveolar IL-8 is related to pulmonary and systemic inflammation in patients predisposed for ARDS. We studied 24 patients 2-6h after mu
Autor:
Shafaqat Ali, Jan Klare, Meike Thomas, Antje Mohs, Michael Schmitz, Michael U. Martin, Ralf Ross
Publikováno v:
The Journal of Immunology. 187:1609-1616
Full-length IL-33 is a member of the IL-1 family of cytokines, which can act in an autocrine or paracrine manner by binding to the IL-33R on several different target cell types. In addition, IL-33 can act in an intracrine fashion by translocating to
Publikováno v:
Biochemical and Biophysical Research Communications. 391:1512-1516
IL-33 is a member of the IL-1 family of cytokines with dual function which either activates cells via the IL-33 receptor in a paracrine fashion or translocates to the nucleus to regulate gene transcription in an intracrine manner. We show that full l
Publikováno v:
Biochemical and Biophysical Research Communications. 354:1089-1094
Ligand binding in the Toll-like/interleukin-1 receptor family results in the recruitment of an intracellular signaling complex. IRAK-1, which is centrally involved in this complex, is able to homo-oligomerize and to bind to Tollip and the adapters My