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Akademický článek

Using bioluminescence as a tool for studying diversity in marine zooplankton and dinoflagellates: an initial assessment

Autor: Francis Letendre, Abigail Blackburn, Ed Malkiel, Michael Twardowski

Publikováno v: PeerJ, Vol 12, p e17516 (2024)

Bioluminescence is light chemically produced by an organism. It is widespread across all major marine phyla and has evolved multiple times, resulting in a high diversity of spectral properties and first flash kinetic parameters (FFKP). The biolumines

Externí odkaz: https://doaj.org/article/e29333a5c76c4ec5ad76568570fc6e19

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Akademický článek

A review of mechanically stimulated bioluminescence of marine plankton and its applications

Autor: Francis Letendre, Michael Twardowski, Abigail Blackburn, Carina Poulin, Michael I. Latz

Publikováno v: Frontiers in Marine Science, Vol 10 (2024)

Bioluminescence is ubiquitous in marine ecosystems and found in uni- and multicellular organisms. Bioluminescent displays can be used to deter predators, attract mates, and lure and hunt prey. Mechanically stimulated flash kinetics of zooplankton and

Externí odkaz: https://doaj.org/article/6ed95c206baa42a38e7f941decb97181

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Akademický článek

Mechanism of Nucleic Acid Sensing in Retinal Pigment Epithelium (RPE): RIG-I Mediates Type I Interferon Response in Human RPE

Autor: Joshua Schustak, Michael Twarog, Xiaoqiu Wu, Henry Y. Wu, Qian Huang, Yi Bao

Publikováno v: Journal of Immunology Research, Vol 2021 (2021)

Age-related macular degeneration (AMD), a degenerative disease of the outer retina, is the leading cause of blindness among the elderly. A hallmark of geographic atrophy (GA), an advanced type of nonneovascular AMD (dry AMD), is photoreceptor and ret

Externí odkaz: https://doaj.org/article/feb4a8d30dc042da87508f4e98666dee

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Micron-scale hysteresis measurement using dynamic optical coherence elastography

Autor: Wenjie Li, Jinping Feng, Yicheng Wang, Qun Shi, Guoqin Ma, Salavat Aglyamov, Kirill V. Larin, Gongpu Lan, Michael Twa

Publikováno v: Biomed Opt Express

We present a novel optical coherence elastography (OCE) method to characterize mechanical hysteresis of soft tissues based on transient (milliseconds), low-pressure (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40efb94a48ed55445aa2844308b2b7da
https://europepmc.org/articles/PMC9203113/

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Akademický článek

TNFα induced by DNA-sensing in macrophage compromises retinal pigment epithelial (RPE) barrier function

Autor: Michael Twarog, Joshua Schustak, YongYao Xu, Matthew Coble, Katie Dolan, Robert Esterberg, Qian Huang, Magali Saint-Geniez, Yi Bao

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)

Abstract Increasing evidence suggests that chronic inflammation plays an important role in the pathogenesis of age-related macular degeneration (AMD); however, the precise pathogenic stressors and sensors, and their impact on disease progression rema

Externí odkaz: https://doaj.org/article/c705bd4509e74127925f63bc280d986c

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Akademický článek

A proteogenomic signature of age-related macular degeneration in blood

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

Age related macular degeneration is a common cause of visual impairment in the elderly, but the etiology is not fully understood. Here, the authors use genetic data, serum proteomics, and AMD phenotypic data from a large Icelandic cohort to discover

Externí odkaz: https://doaj.org/article/74ea238d5b954380bfe2f61fbea0fa44

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Molecular analysis of the VSX1 gene in familial keratoconus

Autor: Petra, Liskova, Neil D, Ebenezer, Pirro G, Hysi, Rhian, Gwilliam, Mohamed F, El-Ashry, Lalitha C, Moodaley, Scott, Hau, Michael, Twa, Stephen J, Tuft, Shomi S, Bhatacharya

Publikováno v: Molecular vision. 13

To evaluate the role of the visual system homeobox gene 1 (VSX1) in the pathogenesis of familial keratoconus.Families with two or more individuals with keratoconus were recruited and their members examined. The coding region and intron-exon junctions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::385b6e10fda3b1acebeb4e272f8e5429
https://pubmed.ncbi.nlm.nih.gov/17960127

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