In vivo mitochondrial function in HIV-infected persons treated with contemporary anti-retroviral therapy: a magnetic resonance spectroscopy study.

Autor: Brendan A I Payne, Kieren G Hollingsworth, Joanne Baxter, Edmund Wilkins, Vincent Lee, D Ashley Price, Michael Trenell, Patrick F Chinnery

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e84678 (2014)

Modern anti-retroviral therapy is highly effective at suppressing viral replication and restoring immune function in HIV-infected persons. However, such individuals show reduced physiological performance and increased frailty compared with age-matche

Externí odkaz: https://doaj.org/article/067b4aa45a4d408caf8944ada298a6aa

Physical activity, inactivity and sleep during the Diabetes Remission Clinical Trial (DiRECT)

Autor: Sophie Cassidy, Michael Trenell, Renae J. Stefanetti, Sarah J. Charman, Alison C. Barnes, Naomi Brosnahan, Louise McCombie, George Thom, Carl Peters, Sviatlana Zhyzhneuskaya, Wilma S. Leslie, Christopher Catt, Michael Catt, Alex McConnachie, Naveed Sattar, Falko F. Sniehotta, Michael E. J. Lean, Roy Taylor

Publikováno v: Diabetic medicine : a journal of the British Diabetic AssociationREFERENCES.

As sustained weight loss is vital for achieving remission of type 2 diabetes, we explored whether randomisation to weight loss plus maintenance in the DiRECT trial was associated with physical activity, inactivity or sleep.Participants were randomise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b444565e9bda90327c4979c3f55d0c
https://pubmed.ncbi.nlm.nih.gov/36398460

Movement as Medicine for Cardiovascular Disease Prevention: Pilot Feasibility Study of a Physical Activity Promotion Intervention for At-Risk Patients in Primary Care (Preprint)

Autor: Sarah Charman, Michael Catt, Falko Sniehotta, Michael Trenell, Sophie O'Connell, Keegan Knittle, Leah Avery

BACKGROUND Physical activity (PA) can reduce cardiovascular disease (CVD) risk factors, and although primary care settings offer a large reach to promote PA and reduce CVD risk, primary health care professionals may lack self-efficacy and tools to ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eeb360bac9a8afee006af281a990e1e5
https://doi.org/10.2196/preprints.29035

Using Wearable Activity Trackers to Predict Type 2 Diabetes: Machine Learning–Based Cross-sectional Study of the UK Biobank Accelerometer Cohort (Preprint)

Autor: Benjamin Lam, Michael Catt, Sophie Cassidy, Jaume Bacardit, Philip Darke, Sam Butterfield, Ossama Alshabrawy, Michael Trenell, Paolo Missier

BACKGROUND Between 2013 and 2015, the UK Biobank collected accelerometer traces from 103,712 volunteers aged between 40 and 69 years using wrist-worn triaxial accelerometers for 1 week. This data set has been used in the past to verify that individua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a87a3b092e99ba1c4bc403e736d4caa
https://doi.org/10.2196/preprints.23364

Cognitive behavioural therapy with optional graded exercise therapy in patients with severe fatigue with myotonic dystrophy type 1: a multicentre, single-blind, randomised trial

Autor: Kees Okkersen, Cecilia Jimenez-Moreno, Stephan Wenninger, Ferroudja Daidj, Jeffrey Glennon, Sarah Cumming, Roberta Littleford, Darren G Monckton, Hanns Lochmüller, Michael Catt, Catharina G Faber, Adrian Hapca, Peter T Donnan, Gráinne Gorman, Guillaume Bassez, Benedikt Schoser, Hans Knoop, Shaun Treweek, Baziel G M van Engelen, Marie Kierkegaard, Darren Monckton, Catharina Faber, Peter Donnan, Baziel van Engelen, Daphne Maas, Stephanie Nikolaus, Yvonne Cornelissen, Marlies van Nimwegen, Ellen Klerks, Sacha Bouman, Linda Heskamp, Arend Heerschap, Ridho Rahmadi, Perry Groot, Tom Heskes, Katarzyna Kapusta, Shaghayegh Abghari, Armaz Aschrafi, Geert Poelmans, Joost Raaphorst, Michael Trenell, Sandra van Laar, Libby Wood, Sophie Cassidy, Jane Newman, Sarah Charman, Renae Steffaneti, Louise Taylor, Allan Brownrigg, Sharon Day, Antonio Atalaya, Fiona Hogarth, Angela Schüller, Kristina Stahl, Heike Künzel, Martin Wolf, Anna Jelinek, Baptiste Lignier, Florence Couppey, Stéphanie Delmas, Jean-François Deux, Karolina Hankiewicz, Celine Dogan, Lisa Minier, Pascale Chevalier, Amira Hamadouche, Berit Adam, Michael Hannah, Emma McKenzie, Petra Rauchhaus, Vincent Van Hees, Sharon Catt, Ameli Schwalber, Ingemar Merkies, Juliane Dittrich

Publikováno v: Lancet Neurology, 17, 671-680
Lancet neurology, 17(8), 671-680. Lancet Publishing Group
Lancet Neurology, 17, 8, pp. 671-680
Lancet Neurology, 17(8), 671-680. Elsevier Science

Background: \ud Myotonic dystrophy type 1 is the most common form of muscular dystrophy in adults and leads to severe fatigue, substantial physical functional impairment, and restricted social participation. In this study, we aimed to determine wheth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d6c0dd11bb724ca61b2edfa09e7325
https://doi.org/10.1016/S1474-4422(18)30203-5