Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Michael Tranter"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
RNA binding proteins (RBPs) play a central in the post-transcriptional regulation of gene expression, which can account for up to 50% of all variations in protein expression within a cell. Following their binding to target RNAs, RBPs most typically c
Externí odkaz:
https://doaj.org/article/2e2fbf0d4c2c4dc8964cd82bb5675cb3
Autor:
Sarah R. Anthony, Adrienne Guarnieri, Lindsey Lanzillotta, Anamarie Gozdiff, Lisa C. Green, Katherine O’Grady, Robert N. Helsley, A. Phillip Owens, Michael Tranter
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 336-346 (2020)
The goal of this study was to define the functional role of adipocyte-specific expression of the RNA binding protein Human antigen R (HuR). Mice with an adipocyte-specific deletion of HuR (Adipo-HuR−/-) were generated by crossing HuR floxed (HuRfl/
Externí odkaz:
https://doaj.org/article/327653bd611d4b6cb45968d881181b15
Autor:
Tyler W. Benson, Kelsey A. Conrad, Xinmin S. Li, Zeneng Wang, Robert N. Helsley, Rebecca C. Schugar, Taylor M. Coughlin, Caris Wadding-Lee, Salma Fleifil, Hannah M. Russell, Timothy Stone, Michael Brooks, Jennifer A. Buffa, Kevin Mani, Martin Björck, Anders Wanhainen, Naseer Sangwan, Sudha Biddinger, Rohan Bhandari, Akiirayi Ademoya, Crystal Pascual, W.H. Wilson Tang, Michael Tranter, Scott J. Cameron, J. Mark Brown, Stanley L. Hazen, A. Phillip Owens
Publikováno v:
Circulation. 147:1079-1096
Background: Large-scale human and mechanistic mouse studies indicate a strong relationship between the microbiome-dependent metabolite trimethylamine N-oxide (TMAO) and several cardiometabolic diseases. This study aims to investigate the role of TMAO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ecd4102d0197c9e127687032c013096
https://doi.org/10.1161/circulationaha.122.060573
https://doi.org/10.1161/circulationaha.122.060573
Autor:
Lisa C, Green, Samuel, Slone, Sarah R, Anthony, Adrienne R, Guarnieri, Sharon, Parkins, Shannon M, Shearer, Michelle L, Nieman, Sudeshna, Roy, Jeffrey, Aube, Xiaoqing, Wu, Liang, Xu, Onur, Kanisicak, Michael, Tranter
Publikováno v:
Journal of Molecular and Cellular Cardiology. 174:38-46
Cardiac fibrosis is regulated by the activation and phenotypic switching of quiescent cardiac fibroblasts to active myofibroblasts, which have extracellular matrix (ECM) remodeling and contractile functions which play a central role in cardiac remode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f600202cd98249e80b2a05b9e799ee94
https://doi.org/10.1016/j.yjmcc.2022.10.007
https://doi.org/10.1016/j.yjmcc.2022.10.007
Autor:
Sharon Parkins, Michael Tranter, Adrienne Guarnieri, Lisa Green, Sarah Anthony, Onur Kanisicak
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Cardiovascular Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90870fdda389e4f17c6043bb7809d6af
https://doi.org/10.1124/jpet.122.255620
https://doi.org/10.1124/jpet.122.255620
Autor:
Rohan Desarapu, Sarah Anthony, Adrienne Guarnieri, Sharon Parkins, Damaris Kuhnell, Scott Langevin, Michael Tranter
Publikováno v:
Physiology. 38
Obesity is a rapidly growing epidemic worldwide, especially in the United States, and is associated with cardiovascular disease (CVD), diabetes, cancer, and a multitude of other comorbidities. Adipose tissue has been shown to act as an endocrine orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c668e10532ed3f7c88e37aa123c50e8
https://doi.org/10.1152/physiol.2023.38.s1.5729547
https://doi.org/10.1152/physiol.2023.38.s1.5729547
Autor:
Samuel Slone, Sarah R. Anthony, Lisa C. Green, Michelle L. Nieman, Perwez Alam, Xiaoqing Wu, Sudeshna Roy, Jeffrey Aube, Liang Xu, John N. Lorenz, A. Phillip Owens, Onur Kanisicak, Michael Tranter
Publikováno v:
bioRxiv
Myocardial ischemia/reperfusion (I/R) injury and the resulting cardiac remodeling is a common cause of heart failure. The RNA binding protein Human Antigen R (HuR) has been previously shown to reduce cardiac remodeling following both I/R and cardiac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c616617f797378b82d427a86bdf37bc
https://europepmc.org/articles/PMC9882229/
https://europepmc.org/articles/PMC9882229/
Autor:
Joshua B. Benoit, Lisa C. Green, Perwez Alam, Salma M Fleifil, Michelle L. Nieman, Onur Kanisicak, A. Phillip Owens, Sam Slone, Anamarie Gozdiff, Michael Tranter, Adrienne R Guarnieri, Sarah R. Anthony
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 321:H228-H241
Adipose tissue homeostasis plays a central role in cardiovascular physiology, and the presence of thermogenically active brown adipose tissue (BAT) has recently been associated with cardiometabolic health. We have previously shown that adipose tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a70e407648093ac0e3c7d39c1a54e591
https://doi.org/10.1152/ajpheart.00957.2020
https://doi.org/10.1152/ajpheart.00957.2020
Autor:
Michael Tranter, Kristin Stanford
Publikováno v:
Circulation research. 131(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16906d0c9032cfe0ecd188ad3bccfe01
https://pubmed.ncbi.nlm.nih.gov/35652349
https://pubmed.ncbi.nlm.nih.gov/35652349
Publikováno v:
Mol Pharmacol
Canonical nonshivering thermogenesis (NST) in brown and beige fat relies on uncoupling protein 1–mediated heat generation, although alternative mechanisms of NST have been identified, including sarcoplasmic reticulum (SR)–calcium cycling. Intrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3b664589ef0eca5b0ac5a95c679603
https://europepmc.org/articles/PMC9341262/
https://europepmc.org/articles/PMC9341262/