Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Michael Toss"'
Autor:
Tanjina Kader, Elena Provenzano, Madawa W. Jayawardana, Shona Hendry, Jia-Min Pang, Kenneth Elder, David J. Byrne, Lauren Tjoeka, Helen ML. Frazer, Eloise House, Sureshni I. Jayasinghe, Holly Keane, Anand Murugasu, Neeha Rajan, Islam M. Miligy, Michael Toss, Andrew R. Green, Emad A. Rakha, Stephen B. Fox, G. Bruce Mann, Ian G. Campbell, Kylie L. Gorringe
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Various histopathological, clinical and imaging parameters have been evaluated to identify a subset of women diagnosed with lesions with uncertain malignant potential (B3 or BIRADS 3/4A lesions) who could safely be observed rather than being
Externí odkaz:
https://doaj.org/article/b48a3f6e9ea54a189ccefd102db6473b
Autor:
Noorul Wahab, Michael Toss, Islam M. Miligy, Mostafa Jahanifar, Nehal M. Atallah, Wenqi Lu, Simon Graham, Mohsin Bilal, Abhir Bhalerao, Ayat G. Lashen, Shorouk Makhlouf, Asmaa Y. Ibrahim, David Snead, Fayyaz Minhas, Shan E. Ahmed Raza, Emad Rakha, Nasir Rajpoot
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-13 (2023)
Abstract Breast cancer (BC) grade is a well-established subjective prognostic indicator of tumour aggressiveness. Tumour heterogeneity and subjective assessment result in high degree of variability among observers in BC grading. Here we propose an ob
Externí odkaz:
https://doaj.org/article/a9e6a8e5c93b4edab4db8a7980977476
Autor:
Ayat Lashen, Abdulbaqi Al-Kawaz, Jennie N Jeyapalan, Shatha Alqahtani, Ahmed Shoqafi, Mashael Algethami, Michael Toss, Andrew R Green, Nigel P Mongan, Sudha Sharma, Mohammad R Akbari, Emad A Rakha, Srinivasan Madhusudan
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 47, Iss , Pp 100957- (2024)
RECQL is essential for genomic stability. Here, we evaluated RECQL in 449 pure ductal carcinomas in situ (DCIS), 152 DCIS components of mixed DCIS/invasive breast cancer (IBC) tumors, 157 IBC components of mixed DCIS/IBC and 50 normal epithelial term
Externí odkaz:
https://doaj.org/article/49f4f85691f14003931c5bd5105aab22
Autor:
Wenqi Lu, Ayat G Lashen, Noorul Wahab, Islam M Miligy, Mostafa Jahanifar, Michael Toss, Simon Graham, Mohsin Bilal, Abhir Bhalerao, Nehal M Atallah, Shorouk Makhlouf, Asmaa Y Ibrahim, David Snead, Fayyaz Minhas, Shan E Ahmed Raza, Emad Rakha, Nasir Rajpoot
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 1, Pp n/a-n/a (2024)
Abstract Early‐stage estrogen receptor positive and human epidermal growth factor receptor negative (ER+/HER2−) luminal breast cancer (BC) is quite heterogeneous and accounts for about 70% of all BCs. Ki67 is a proliferation marker that has a sig
Externí odkaz:
https://doaj.org/article/6a155cf9d05147a98b8a08c72dc26ccc
RANK is a poor prognosis marker and a therapeutic target in ER‐negative postmenopausal breast cancer
Autor:
Marina Ciscar, Eva M Trinidad, Gema Perez‐Chacon, Mansour Alsaleem, Maria Jimenez, Maria J Jimenez‐Santos, Hector Perez‐Montoyo, Adrian Sanz‐Moreno, Andrea Vethencourt, Michael Toss, Anna Petit, Maria T Soler‐Monso, Victor Lopez, Jorge Gomez‐Miragaya, Clara Gomez‐Aleza, Lacey E Dobrolecki, Michael T Lewis, Alejandra Bruna, Silvana Mouron, Miguel Quintela‐Fandino, Fatima Al‐Shahrour, Antonio Martinez‐Aranda, Angels Sierra, Andrew R Green, Emad Rakha, Eva Gonzalez‐Suarez
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 4, Pp 1-12 (2023)
Abstract Despite strong preclinical data, the therapeutic benefit of the RANKL inhibitor, denosumab, in breast cancer patients, beyond the bone, is unclear. Aiming to select patients who may benefit from denosumab, we hereby analyzed RANK and RANKL p
Externí odkaz:
https://doaj.org/article/1a7e932a6a184ce6a384d4a58e43a0be
Autor:
Noorul Wahab, Islam M Miligy, Katherine Dodd, Harvir Sahota, Michael Toss, Wenqi Lu, Mostafa Jahanifar, Mohsin Bilal, Simon Graham, Young Park, Giorgos Hadjigeorghiou, Abhir Bhalerao, Ayat G Lashen, Asmaa Y Ibrahim, Ayaka Katayama, Henry O Ebili, Matthew Parkin, Tom Sorell, Shan E Ahmed Raza, Emily Hero, Hesham Eldaly, Yee Wah Tsang, Kishore Gopalakrishnan, David Snead, Emad Rakha, Nasir Rajpoot, Fayyaz Minhas
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 2, Pp 116-128 (2022)
Abstract Recent advances in whole‐slide imaging (WSI) technology have led to the development of a myriad of computer vision and artificial intelligence‐based diagnostic, prognostic, and predictive algorithms. Computational Pathology (CPath) offer
Externí odkaz:
https://doaj.org/article/0ab322726d414a3280ea866dedb9d11e
Publikováno v:
Diagnostic Histopathology. 29:71-74
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20cb188ca855a1d5d7046874d4d5dd22
https://doi.org/10.1016/j.mpdhp.2022.10.007
https://doi.org/10.1016/j.mpdhp.2022.10.007
Autor:
Mashael A. Algethami, Michael Toss, Juliette Brownlie, Corinne L. Woodcock, Chandar Jaipal, AHMED SHOQAFI, Katia Mesquita, Adel Alblihy, Nigel Mongan, Emad Rakha, Jennie N. Jeyapalan, Srinivasan Madhusudan, Andrew R. Green
Publikováno v:
Cancer Research. 83:P3-05
Unravelling the clinicopathological and functional significance of Replication Protein A (RPA) heterotrimeric complex in sporadic breast cancers Mashael Algethami1, Michael S Toss 1,4, Juliette Brownlie 1, Corinne L Woodcock 1,2, Chandar Jaipal1, Ahm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a685d535a7c5fbf5f6b3a75a357a85f1
https://doi.org/10.1158/1538-7445.sabcs22-p3-05-18
https://doi.org/10.1158/1538-7445.sabcs22-p3-05-18
Autor:
Marina Ciscar, Eva M Trinidad, Gema Perez‐Chacon, Mansour Alsaleem, Maria Jimenez, Maria J Jimenez‐Santos, Hector Perez‐Montoyo, Adrian Sanz‐Moreno, Andrea Vethencourt, Michael Toss, Anna Petit, Maria T Soler‐Monso, Victor Lopez, Jorge Gomez‐Miragaya, Clara Gomez‐Aleza, Lacey E Dobrolecki, Michael T Lewis, Alejandra Bruna, Silvana Mouron, Miguel Quintela‐Fandino, Fatima Al‐Shahrour, Antonio Martinez‐Aranda, Angels Sierra, Andrew R Green, Emad Rakha, Eva Gonzalez‐Suarez
Publikováno v:
EMBO Molecular Medicine. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62c108380550b08bff4430c30a01ca09
https://doi.org/10.15252/emmm.202216715
https://doi.org/10.15252/emmm.202216715
Differential gene expression analysis unravels key genes associated with breast cancer proliferation
Background: Improved understanding of breast cancer (BC) complex molecular pathways is required to predict prognosis and develop new therapeutic strategies. The purpose of this study is to apply an integrated approach that combine both clinical and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf8f484f4f8b4955f4946b618f3968b6
https://doi.org/10.21203/rs.3.rs-1906644/v1
https://doi.org/10.21203/rs.3.rs-1906644/v1
