Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Michael Topper"'
Autor:
J. Tyson McDonald, JangKeun Kim, Lily Farmerie, Meghan L. Johnson, Nidia S. Trovao, Shehbeel Arif, Keith Siew, Sergey Tsoy, Yaron Bram, Jiwoon Park, Eliah Overbey, Krista Ryon, Jeffrey Haltom, Urminder Singh, Francisco J. Enguita, Victoria Zaksas, Joseph W. Guarnieri, Michael Topper, Douglas C. Wallace, Cem Meydan, Stephen Baylin, Robert Meller, Masafumi Muratani, D. Marshall Porterfield, Brett Kaufman, Marcelo A. Mori, Stephen B. Walsh, Dominique Sigaudo-Roussel, Saida Mebarek, Massimo Bottini, Christophe A. Marquette, Eve Syrkin Wurtele, Robert E. Schwartz, Diego Galeano, Christopher E. Mason, Peter Grabham, Afshin Beheshti
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Our previous research revealed a key microRNA signature that is associated with spaceflight that can be used as a biomarker and to develop countermeasure treatments to mitigate the damage caused by space radiation. Here, we expand on this wo
Externí odkaz:
https://doaj.org/article/0649faa161fd46558b42240dde0a9327
Autor:
Rossin Erbe, Zheyu Wang, Sharon Wu, Joanne Xiu, Neeha Zaidi, Jennifer La, David Tuck, Nathanael Fillmore, Nicolas A. Giraldo, Michael Topper, Stephen Baylin, Marc Lippman, Claudine Isaacs, Reva Basho, Ilya Serebriiskii, Heinz-Josef Lenz, Igor Astsaturov, John Marshall, Josephine Taverna, Jerry Lee, Elizabeth M. Jaffee, Evanthia T. Roussos Torres, Ashani Weeraratna, Hariharan Easwaran, Elana J. Fertig
Publikováno v:
Cell Reports, Vol 37, Iss 7, Pp 110033- (2021)
Externí odkaz:
https://doaj.org/article/1929927bbd9e4b6ca3ee96700e38831f
Autor:
Michael Kalos, Dale L. Ludwig, Gregory D. Plowman, Christopher M. Moxham, Ruslan D. Novosiadly, Jaafar N. Haidar, Andreas Sonyi, Darin Chin, Stacy Torgerson, Bing Han, Yanbin Lao, Tim Bailey, Danielle K. Bulaon, Yiwei Zhang, Xinlei Chen, Michael Topper, Sagit Hindi, Krishnadatt Persaud, Anthony L. Pennello, David Surguladze, Ivan Inigo, George Wang, Yang Shen, Scott W. Eastman, Carmine Carpenito, Maria Malabunga, Yiwen Li, Helen Kotanides
The programmed cell death protein 1 receptor (PD-1) and programmed death ligand 1 (PD-L1) coinhibitory pathway suppresses T-cell–mediated immunity. We hypothesized that cotargeting of PD-1 and PD-L1 with a bispecific antibody molecule could provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1986ead76832948fc92b79c10618c0e0
https://doi.org/10.1158/2326-6066.c.6550090
https://doi.org/10.1158/2326-6066.c.6550090
Autor:
Michael Kalos, Dale L. Ludwig, Gregory D. Plowman, Christopher M. Moxham, Ruslan D. Novosiadly, Jaafar N. Haidar, Andreas Sonyi, Darin Chin, Stacy Torgerson, Bing Han, Yanbin Lao, Tim Bailey, Danielle K. Bulaon, Yiwei Zhang, Xinlei Chen, Michael Topper, Sagit Hindi, Krishnadatt Persaud, Anthony L. Pennello, David Surguladze, Ivan Inigo, George Wang, Yang Shen, Scott W. Eastman, Carmine Carpenito, Maria Malabunga, Yiwen Li, Helen Kotanides
Supplementary Figures 1-9 and Supplementary Tables 1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae9b70f08e357e6f6d0737e3afa7b80
https://doi.org/10.1158/2326-6066.22542937.v1
https://doi.org/10.1158/2326-6066.22542937.v1
Autor:
Michael Kalos, Gregory D. Plowman, Dale L. Ludwig, Ruslan D. Novosiadly, Douglas Burtrum, Yiwei Zhang, Prachi Sharma, Lauren Boucher, Michael Topper, Andreas Sonyi, Darin Chin, Xinlei Chen, Amelie Forest, Anthony L. Pennello, Ivan Inigo, Leyi Shen, Colleen Burns, Jaafar N. Haidar, David Surguladze, Jingxing Li, Juqun Shen, Carmine Carpenito, Maria B. Lebron, Rose Marie Sattler, Helen Kotanides
Figure S3 shows CD137 receptor modulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3bb6a3afe5cfbbb01f18d1ddaccd41
https://doi.org/10.1158/1535-7163.22519410
https://doi.org/10.1158/1535-7163.22519410
Autor:
Michael Kalos, Gregory D. Plowman, Dale L. Ludwig, Ruslan D. Novosiadly, Douglas Burtrum, Yiwei Zhang, Prachi Sharma, Lauren Boucher, Michael Topper, Andreas Sonyi, Darin Chin, Xinlei Chen, Amelie Forest, Anthony L. Pennello, Ivan Inigo, Leyi Shen, Colleen Burns, Jaafar N. Haidar, David Surguladze, Jingxing Li, Juqun Shen, Carmine Carpenito, Maria B. Lebron, Rose Marie Sattler, Helen Kotanides
Table S2 shows human immune effector ADCC and CDC activity EC50 (nM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a7d8844ae274ecd96486d49338c0e0
https://doi.org/10.1158/1535-7163.22519383
https://doi.org/10.1158/1535-7163.22519383
Autor:
Michael Kalos, Gregory D. Plowman, Dale L. Ludwig, Ruslan D. Novosiadly, Douglas Burtrum, Yiwei Zhang, Prachi Sharma, Lauren Boucher, Michael Topper, Andreas Sonyi, Darin Chin, Xinlei Chen, Amelie Forest, Anthony L. Pennello, Ivan Inigo, Leyi Shen, Colleen Burns, Jaafar N. Haidar, David Surguladze, Jingxing Li, Juqun Shen, Carmine Carpenito, Maria B. Lebron, Rose Marie Sattler, Helen Kotanides
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20e7787d1efd66b5f6dc06f92584d9f
https://doi.org/10.1158/1535-7163.22519389
https://doi.org/10.1158/1535-7163.22519389
Autor:
Kathryn M. Ferguson, Ruslan D. Novosiadly, Yang Shen, Amelie Forest, Jason M. Walker, Michelle D. Iacolina, Michael Topper, Michal Vieth, Scott W. Eastman, Jaafar N. Haidar, Atrish Bagchi
Supplementary Table S1 - Therapeutic antibody induced EGFR ECR mutations; Supplementary Table S2 - Mean SPR KD values for binding of wild type (WT) and cetuximab resistance variants of sEGFR to immobilized Fab fragments from cetuximab (FabC225) and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d92447c8e255cf0b039b66a1add238
https://doi.org/10.1158/1535-7163.22510134
https://doi.org/10.1158/1535-7163.22510134
Autor:
J. Tyson McDonald, Lily Farmerie, Meghan Johnson, Jiwoon Park, JangKeun Kim, Eliah Overbey, Jeffrey Haltom, Urminder Singh, Eve Syrkin Wurtele, Francisco Enguita, Victoria Zaksas, Joseph Guarnieri, Michael Topper, Douglas Wallace, Stephen Baylin, Robert Meller, Masafumi Muratani, D. Marshall Porterfield, Brett Kaufman, Marcelo Mori, Christopher Mason, Peter Grabham, Afshin Beheshti
From our previous work we have shown a key miRNA signature that is associated with spaceflight can be used as a biomarker and countermeasure to mitigate the damage caused by space radiation. Here, we have further expanded on this work to determine ke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b6ef51f65d51e4e3f984a92775e0192
https://doi.org/10.21203/rs.3.rs-2370597/v1
https://doi.org/10.21203/rs.3.rs-2370597/v1
Autor:
Michael Topper
Publikováno v:
Journal of Human Resources. :0722-12422R1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51e61b7969b9ff7034f3bd989ab32700
https://doi.org/10.3368/jhr.0722-12422r1
https://doi.org/10.3368/jhr.0722-12422r1