Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Michael Timaner"'
Autor:
Rostislav Novak, Yamen Abu Ahmad, Michael Timaner, Eliya Bitman-Lotan, Avital Oknin-Vaisman, Roi Horwitz, Oliver Hartmann, Michaela Reissland, Viktoria Buck, Mathias Rosenfeldt, David Nikomarov, Markus Elmar Diefenbacher, Yuval Shaked, Amir Orian
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-12 (2022)
Abstract Molecular understanding of osteogenic differentiation (OD) of human bone marrow-derived mesenchymal stem cells (hBMSCs) is important for regenerative medicine and has direct implications for cancer. We report that the RNF4 ubiquitin ligase i
Externí odkaz:
https://doaj.org/article/b0277c5b77ee4bf686658fdcd6fc4695
Autor:
Madeleine Benguigui, Avital Vorontsova, Michael Timaner, Sapir Levin, Jozafina Haj-Shomaly, Abhilash Deo, Rotem Menachem, Bar Manobla, Tim J. Cooper, Ziv Raviv, Yuval Shaked
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Myeloid-derived suppressor cells (MDSCs) are known to promote tumor growth in part by their immunosuppressive activities and their angiogenesis support. It has been shown that Bv8 blockade inhibits the recruitment of MDSCs to tumors, thereby delaying
Externí odkaz:
https://doaj.org/article/dfdc5e1ca1d0488799c8de402783321b
Autor:
Michael Timaner, Ziv Raviv, Shai Shen-Orr, Yuval Shaked, Tongwu Zhang, Ksenia Magidey-Klein, Tim J Cooper, Ksenya Kveler, Rachelly Normand, Brian P. James, Roi Gazit, Ze'ev A. Ronai
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Metastasis is the major cause of death in patients with cancer. Myeloid skewing of hematopoietic cells is a prominent promoter of metastasis. However, the reservoir of these cells in the bone marrow (BM) compartment and their differentiati
Externí odkaz:
https://doaj.org/article/b1eb6c9ab4594ba7bc4b1dc99865ddec
Autor:
Michael Timaner, Ziv Raviv, Shai Shen-Orr, Yuval Shaked, Tongwu Zhang, Ksenia Magidey-Klein, Tim J Cooper, Ksenya Kveler, Rachelly Normand, Brian P. James, Roi Gazit, Ze'ev A. Ronai
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Externí odkaz:
https://doaj.org/article/d52b571268c14be3a4db3fc9ccc60dcd
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Immunomodulatory agents that induce antitumor immunity have great potential for treatment of cancer. We have previously shown that interleukin (IL)-31, a proinflammatory cytokine from the IL-6 family, acts as an antiangiogenic agent. Here,
Externí odkaz:
https://doaj.org/article/7d9ec16b9d2a4589b68fcef2e01d3fdd
Autor:
Chen Rachman-Tzemah, Shelly Zaffryar-Eilot, Moran Grossman, Dario Ribero, Michael Timaner, Joni M. Mäki, Johanna Myllyharju, Francesco Bertolini, Dov Hershkovitz, Irit Sagi, Peleg Hasson, Yuval Shaked
Publikováno v:
Cell Reports, Vol 19, Iss 4, Pp 774-784 (2017)
Surgery remains the most successful curative treatment for cancer. However, some patients with early-stage disease who undergo surgery eventually succumb to distant metastasis. Here, we show that in response to surgery, the lungs become more vulnerab
Externí odkaz:
https://doaj.org/article/2686e8bc65004844a77588d2f1547c24
Autor:
Dror Alishekevitz, Svetlana Gingis-Velitski, Orit Kaidar-Person, Lilach Gutter-Kapon, Sandra D. Scherer, Ziv Raviv, Emmanuelle Merquiol, Yael Ben-Nun, Valeria Miller, Chen Rachman-Tzemah, Michael Timaner, Yelena Mumblat, Neta Ilan, David Loven, Dov Hershkovitz, Ronit Satchi-Fainaro, Galia Blum, Jonathan P. Sleeman, Israel Vlodavsky, Yuval Shaked
Publikováno v:
Cell Reports, Vol 17, Iss 5, Pp 1344-1356 (2016)
Summary: While chemotherapy strongly restricts or reverses tumor growth, the response of host tissue to therapy can counteract its anti-tumor activity by promoting tumor re-growth and/or metastases, thus limiting therapeutic efficacy. Here, we show t
Externí odkaz:
https://doaj.org/article/33aac968c8234da399706c8ab64ff755
Chemotherapy-induced tumor immunogenicity is mediated in part by megakaryocyte-erythroid progenitors
Autor:
Avital Vorontsova, Tim J. Cooper, Jozafina Haj-Shomaly, Madeleine Benguigui, Sapir Levin, Bar Manobla, Rotem Menachem, Michael Timaner, Ziv Raviv, Yuval Shaked
Publikováno v:
Oncogene. 42:771-781
Chemotherapy remains one of the main treatment modalities for cancer. While chemotherapy is mainly known for its ability to kill tumor cells directly, accumulating evidence indicates that it also acts indirectly by enhancing T cell-mediated anti-tumo
Autor:
Yuval Shaked, Ruth Scherz-Shouval, Daphne Weihs, Peleg Hasson, Shay Soker, Tim J. Cooper, Ziv Raviv, Michael Timaner, Mahesh Devarasetty, Oshrat Levi-Galibov, Tamar Barenholz-Cohen, Avital Vorontsova, Jozafina Haj-Shomaly
supplemental materials and methods and supplemental figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f34a0f5448f772aab33f594ffb1f4bc
https://doi.org/10.1158/0008-5472.22582427.v1
https://doi.org/10.1158/0008-5472.22582427.v1
Autor:
Yuval Shaked, Ruth Scherz-Shouval, Daphne Weihs, Peleg Hasson, Shay Soker, Tim J. Cooper, Ziv Raviv, Michael Timaner, Mahesh Devarasetty, Oshrat Levi-Galibov, Tamar Barenholz-Cohen, Avital Vorontsova, Jozafina Haj-Shomaly
Metastasis is the main cause of cancer-related mortality. Despite intense efforts to understand the mechanisms underlying the metastatic process, treatment of metastatic cancer is still challenging. Here we describe a chemotherapy-induced, host-media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab98c365cdd35805965055294c15d9d
https://doi.org/10.1158/0008-5472.c.6570581
https://doi.org/10.1158/0008-5472.c.6570581