A novel platform for attenuating immune hyperactivity using EXO‐CD24 in COVID‐19 and beyond

Autor: Shiran Shapira, Marina Ben Shimon, Mori Hay‐Levi, Gil Shenberg, Guy Choshen, Lian Bannon, Michael Tepper, Dina Kazanov, Jonathan Seni, Shahar Lev‐Ari, Michael Peer, Dimitrios Boubas, Justin Stebbing, Sotirios Tsiodras, Nadir Arber

Publikováno v: EMBO Molecular Medicine, Vol 14, Iss 9, Pp 1-17 (2022)

Abstract A small but significant proportion of COVID‐19 patients develop life‐threatening cytokine storm. We have developed a new anti‐inflammatory drug, EXO‐CD24, a combination of an immune checkpoint (CD24) and a delivery platform (exosomes

Externí odkaz: https://doaj.org/article/e8cb646be73748bdab517e8146718ff6

Resultant and conductor of geometrically semi-stable self maps of the projective line over a number field or function field

Autor: Michael Tepper, Lucien Szpiro, Phillip Williams

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Publ. Mat. 58, no. 2 (2014), 295-329
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Publicacions Matemàtiques; Vol. 58, Núm. 2 (2014); p. 295-329

We study the minimal resultant divisor of self-maps of the projective line over a number field or a function field and its relation to the conductor. The guiding focus is the exploration of a dynamical analog to Theorem 1.1, which bounds the degree o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3281387a298f45b95093d6ffce8a4aca
https://doi.org/10.5565/publmat_58214_15

Isotriviality is equivalent to potential good reduction for endomorphisms of PN over function fields

Autor: Lucien Szpiro, Clayton Petsche, Michael Tepper

Publikováno v: Journal of Algebra. 322:3345-3365

Let K = k ( C ) be the function field of a complete non-singular curve C over an arbitrary field k. The main result of this paper states that a morphism φ : P K N → P K N is isotrivial if and only if it has potential good reduction at all places v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc26907ef716b418338faaa5928b536b
https://doi.org/10.1016/j.jalgebra.2008.11.027

A Novel Access to Tertiary and Secondary ortho-Aminophenylphosphines by Protected Group Synthesis and Palladium Catalyzed P-C Coupling Reactions

Autor: Michael Tepper, Stefan Schenk, Konstantin W. Kottsieper, Antonella Heßler, Othmar Stelzer

Publikováno v: Zeitschrift für Naturforschung B. 56:347-353

The dilithium salt 1a formed by ortho-metallation of N-tert-butoxycarbonylaniline (BOC-aniline) 1 with two equivalents of tert-butyllithium reacts with the chlorophosphines Ph3-nPCln (n = 1 -3) to yield the BOC protected ortho-aminophenylphosphines 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::716c3c10bf9607e5e62ce3aa4d3068f8
https://doi.org/10.1515/znb-2001-4-504

Wasserlösliche Phosohane, XIV. Hydrophile Derivate des Triphenylphosphans mit NH2-, COOH- und P(O)(OR)2-funktionalisierten Seitenketten / Water Soluble Phosphanes, XIV. Hydrophilic Derivatives of Triphenylphosphane with NH2, COOH and P (O)(OR)2 Functionalized Side Chains

Autor: Peter Machnitzki, Stefan Schenk, Michael Tepper, Christian Liek, Thomas Nickel, Othmar Stelzer

Publikováno v: Zeitschrift für Naturforschung B. 54:1532-1542

Nucleophilic phosphanylation of ortho-fluorophenylacetic acid or ortho-fluorobenzylamine with PhPH2 using KOtBu as the base affords the hydrophilic tertiary phosphanes 3 and 4a with terminal CH2-COOH and CH2-NH2 substituents. The corresponding second

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::097fda5c60c2b212e95a3e89930887d6
https://doi.org/10.1515/znb-1999-1210