Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Michael Tarasev"'
Autor:
Marty Emanuele, Jennell White, S. Chakraborty, Michael Tarasev, Lancelot Moira, Xiufeng Gao, Patrick C. Hines
Publikováno v:
Clinical Hemorheology and Microcirculation. 80:127-138
BACKGROUND: Red blood cell (RBC)-modifying therapies have provided new opportunities for patients with sickle cell disease, although the absence of validated biomarkers of RBC function is a barrier to FDA approval and clinical adoption. Flow Adhesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e460b9c162a125825b2cb74634fd20c9
https://doi.org/10.3233/ch-200944
https://doi.org/10.3233/ch-200944
Autor:
Ahmar U. Zaidi, Michael Tarasev, Xiufeng Gao, Ke Liu, Jennell White, Patrick C. Hines, Michael U. Callaghan
Publikováno v:
British Journal of Haematology. 196:1052-1058
Sickle cell disease (SCD) is characterized by frequent and unpredictable vaso-occlusive crises (VOCs). Sickle erythrocytes (SSRBCs) contribute to VOCs by participating in a series of adhesive events with blood cells and the vascular endothelium. Adhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a12262ee51b15d1bb1bc77296125bb
https://doi.org/10.1111/bjh.17954
https://doi.org/10.1111/bjh.17954
Autor:
Xiufeng Gao, Ahmar U. Zaidi, Michael U. Callaghan, Patrick C. Hines, Jennell White, Ke Liu, Michael Tarasev
Publikováno v:
British Journal of Haematology. 194:1074-1082
Blood cell adhesion to P-selectin and vascular cell adhesion molecule-1 (VCAM-1) contributes to the pathophysiology of vaso-occlusion crisis (VOC) events in individuals with sickle cell disease (SCD). We evaluated the use of standardized flow adhesio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2101c9bef5d76e98e4a53fc6ed23354d
https://doi.org/10.1111/bjh.17643
https://doi.org/10.1111/bjh.17643
Sickle cell disease (SCD) is characterized by frequent and unpredictable vaso-occlusive crises (VOCs) resulting in increased morbidity and mortality. Reliable biomarkers that predict the onset and progression of VOCs in SCD are unavailable, thus the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3abf909342f50ef1686f2f2c9f0b3aef
https://doi.org/10.1101/2022.10.20.22281335
https://doi.org/10.1101/2022.10.20.22281335
Autor:
Michael Tarasev, Xiufeng Gao, Marta Ferranti, Robert Goodrich, Allie Edenstrom, Aliya Zaidi, Patrick C. Hines
Publikováno v:
Blood. 140:4976-4977
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec916fc91cf642ecb4210a5649583931
https://doi.org/10.1182/blood-2022-170885
https://doi.org/10.1182/blood-2022-170885
Autor:
Michael Tarasev, Sabrina Mota, Xiufeng Gao, Marta Ferranti, Aliya U. Zaidi, Bryan Hannan, Patrick Hines
BackgroundLong-term outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are now recognized as an emerging public health challenge - a condition termed Long-COVID. The pathophysiology of Long-COVID remains to be established. Funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23a8dc48e2786d408a255a3643ed279d
https://doi.org/10.1101/2022.03.09.22271297
https://doi.org/10.1101/2022.03.09.22271297
Publikováno v:
Am J Transl Res
A lack of objective metrics in Sickle Cell Disease (SCD) makes it difficult to assess individual patient therapy options or assess the effects of therapy. This is further complicated by mechanisms of action involving multiple interconnected effects,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6c86336703797f0b155343d04c7e507
https://pubmed.ncbi.nlm.nih.gov/35173841
https://pubmed.ncbi.nlm.nih.gov/35173841
Autor:
Michael Tarasev, Marta Ferranti, Cidney Allen, Xiufeng Gao, Kayla Topping, Biola Makinde-Odesola, Lanetta Bronté-Hall, Patrick Hines
Publikováno v:
Blood. 138:959-959
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause severe vascular complications associated with endothelial dysfunction and systemic inflammation. COVID19-specific IgG are detectable within a week of infection. Long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e293f68eef796867ed708086f94c7ed
https://doi.org/10.1182/blood-2021-154308
https://doi.org/10.1182/blood-2021-154308
Autor:
Patrick C. Hines, Janet L. Kwiatkowski, Xiufeng Gao, Meera Chitlur, Wendy Hollon, Andrew Herppich, Michael Tarasev
Publikováno v:
Blood. 138:923-923
Introduction Pyruvate Kinase Deficiency (PKD) is an inherited glycolytic enzymopathy that is characterized by a life-long chronic hemolytic anemia with severe comorbidities. Hypercoagulability due to increased platelet activity caused by nitric oxide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19df6c138f3811f2dc0fdc3e268e5deb
https://doi.org/10.1182/blood-2021-149744
https://doi.org/10.1182/blood-2021-149744
Publikováno v:
Translational Research. 181:96-107
Hemoglobin S (Hb-S) polymerization is the primary event in sickle cell disease causing irreversible damage to red blood cell (RBC) membranes over repeated polymerization cycles. A single polymerization triggered by a hypoxic environment was reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a1df3ef32668a983b394ec0725ab13
https://doi.org/10.1016/j.trsl.2016.09.005
https://doi.org/10.1016/j.trsl.2016.09.005