Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michael Takla"'
Autor:
Norman Zerbe, Lars Ole Schwen, Christian Geißler, Katja Wiesemann, Tom Bisson, Peter Boor, Rita Carvalho, Michael Franz, Christoph Jansen, Tim-Rasmus Kiehl, Björn Lindequist, Nora Charlotte Pohlan, Sarah Schmell, Klaus Strohmenger, Falk Zakrzewski, Markus Plass, Michael Takla, Tobias Küster, André Homeyer, Peter Hufnagl
Publikováno v:
Journal of Pathology Informatics, Vol 15, Iss , Pp 100387- (2024)
Over the past decade, artificial intelligence (AI) methods in pathology have advanced substantially. However, integration into routine clinical practice has been slow due to numerous challenges, including technical and regulatory hurdles in translati
Externí odkaz:
https://doaj.org/article/224c25035ba642a39b737874f9152e0c
Autor:
Michael Takla, Kamalan Jeevaratnam
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 12, Pp 1760-1776 (2020)
The COVID-19 pandemic has required clinicians to urgently identify new treatment options or the re-purposing of existing drugs. Of particular interest are chloroquine (CQ) and hydroxychloroquine (HCQ). The aims of this systematic review are to system
Externí odkaz:
https://doaj.org/article/0fec8895fddd4734ad8b34d92c6f0224
Transcriptional profiles of genes related to electrophysiological function in Scn5a+/− murine hearts
Autor:
Michael Takla, Charlotte E. Edling, Kevin Zhang, Khalil Saadeh, Gary Tse, Samantha C. Salvage, Christopher L.‐H. Huang, Kamalan Jeevaratnam
Publikováno v:
Physiological Reports, Vol 9, Iss 19, Pp n/a-n/a (2021)
Abstract The Scn5a gene encodes the major pore‐forming Nav1.5 (α) subunit, of the voltage‐gated Na+ channel in cardiomyocytes. The key role of Nav1.5 in action potential initiation and propagation in both atria and ventricles predisposes organis
Externí odkaz:
https://doaj.org/article/edef003b381440f3af65dbd7393d25d6
Publikováno v:
Subcellular Biochemistry ISBN: 9783031265754
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c347b72e32d93a09f6ed811fb2bca9ec
https://doi.org/10.1007/978-3-031-26576-1_10
https://doi.org/10.1007/978-3-031-26576-1_10
Publikováno v:
Journal of Molecular and Cellular Cardiology. 139:190-200
The SCN5A gene encodes Nav1.5, which, as the cardiac voltage-gated Na+ channel's pore-forming α subunit, is crucial for the initiation and propagation of atrial and ventricular action potentials. The arrhythmogenic propensity of inherited SCN5A muta
Transcriptional profiles of genes related to electrophysiological function in Scn5a+/- murine hearts
Autor:
Samantha C. Salvage, Kamalan Jeevaratnam, Charlotte E. Edling, Michael Takla, Gary Tse, Khalil Saadeh, Christopher L.-H. Huang, Kevin Zhang
Publikováno v:
Physiological Reports, Vol 9, Iss 19, Pp n/a-n/a (2021)
Funder: University of Surrey; Id: http://dx.doi.org/10.13039/501100003513
The Scn5a gene encodes the major pore‐forming Nav1.5 (α) subunit, of the voltage‐gated Na+ channel in cardiomyocytes. The key role of Nav1.5 in action potential initi
The Scn5a gene encodes the major pore‐forming Nav1.5 (α) subunit, of the voltage‐gated Na+ channel in cardiomyocytes. The key role of Nav1.5 in action potential initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1441935c644dcf3b2a59408139218e50
Autor:
Daniel Romberg, Klaus Strohmenger, Christoph Jansen, Tobias Küster, Nick Weiss, Christian Geißler, Tomasz Sołtysiński, Michael Takla, Peter Hufnagl, Norman Zerbe, André Homeyer
Publikováno v:
Computer Methods and Programs in Biomedicine. 215:106596
Background and objective: Artificial intelligence (AI) apps hold great potential to make pathological diagnoses more accurate and time efficient. Widespread use of AI in pathology is hampered by interface incompatibilities between pathology software.
Autor:
Michael Takla, Kamalan Jeevaratnam
BackgroundThe COVID-19 pandemic has required clinicians to urgently identify new treatment options or the repurposing of existing drugs. Several drugs are now being repurposed with the aim of identifying if these drugs provide some level of disease r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1f994d99724fc9476dd98c4ce856d1
https://doi.org/10.1101/2020.05.28.20115741
https://doi.org/10.1101/2020.05.28.20115741
Publikováno v:
Journal of molecular and cellular cardiology. 139
The SCN5A gene encodes Na