Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Michael T. Yang"'
Autor:
Su-Jin Heo, Tristan P Driscoll, Stephen D Thorpe, Nandan L Nerurkar, Brendon M Baker, Michael T Yang, Christopher S Chen, David A Lee, Robert L Mauck
Publikováno v:
eLife, Vol 5 (2016)
Mesenchymal stem cell (MSC) differentiation is mediated by soluble and physical cues. In this study, we investigated differentiation-induced transformations in MSC cellular and nuclear biophysical properties and queried their role in mechanosensation
Externí odkaz:
https://doaj.org/article/16c1483368c14410ae3abebcf88a3596
Autor:
Kristin A. Knouse, Christopher S. Chen, Michael T. Yang, Ritika Chaturvedi, Kwanghun Chung, Jing W. Xiao, Chelsea L. Fortin, Heather E. Fleming, Canny Fung, Vyas Ramanan, Sangeeta N. Bhatia, Amanda X. Chen, Ype P. de Jong, Kelly R. Stevens, Margaret McCue, Charles M. Rice, Teodelinda Mirabella, Margaret A. Scull
In spite of the vast collective experience in tissue engineering, control of both tissue architecture and scale are fundamental translational roadblocks. An experimental framework that enables investigation into how architecture and scaling may be co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcfbdc18b5a3af569a8f8fb56d81db5
https://europepmc.org/articles/PMC5896001/
https://europepmc.org/articles/PMC5896001/
Publikováno v:
Cellular and Molecular Bioengineering. 7:26-34
Rigidity sensing plays a fundamental role in multiple cell functions ranging from migration, to proliferation and differentiation (Engler et al., Cell 126:677–689, 2006; Lo et al., Biophys. J. 79:144–152, 2000; Wells, Hepatology 47:1394–1400, 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d99e8ab9eedcf1426cee687e1cd6269
https://doi.org/10.1007/s12195-013-0307-6
https://doi.org/10.1007/s12195-013-0307-6
Autor:
Christopher S. Chen, Ricardo D. Solorzano, Ritika Chaturvedi, Kelly R. Stevens, Jan D. Baranski, Brian Carvalho, Michael T. Yang, Jeroen Eyckmans, Jordan S. Miller, Sangeeta N. Bhatia
Publikováno v:
Proceedings of the National Academy of Sciences. 110:7586-7591
Tissue vascularization and integration with host circulation remains a key barrier to the translation of engineered tissues into clinically relevant therapies. Here, we used a microtissue molding approach to demonstrate that constructs containing hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a0d99d0705751c084c45a7b1bb18cd
https://doi.org/10.1073/pnas.1217796110
https://doi.org/10.1073/pnas.1217796110
Autor:
Susie S. Cha, Sarah C. Stapleton, Michael T. Yang, Christopher S. Chen, Peter A. Galie, Colin K. Choi, Duc-Huy T. Nguyen
Publikováno v:
Proceedings of the National Academy of Sciences. 110:6712-6717
Angiogenesis is a complex morphogenetic process whereby endothelial cells from existing vessels invade as multicellular sprouts to form new vessels. Here, we have engineered a unique organotypic model of angiogenic sprouting and neovessel formation t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508c0c27d758f727b47495b449ce831a
https://doi.org/10.1073/pnas.1221526110
https://doi.org/10.1073/pnas.1221526110
Autor:
Nandan L. Nerurkar, Michael T. Yang, Su Jin Heo, Christopher S. Chen, Tristan P. Driscoll, Robert L. Mauck, Stephen D. Thorpe, David A. Lee, Brendon M. Baker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97b4a41884bb1a243e3ee7365eaf15c9
https://doi.org/10.7554/elife.18207.028
https://doi.org/10.7554/elife.18207.028
Autor:
David A. Lee, Nandan L. Nerurkar, Su Jin Heo, Tristan P. Driscoll, Brendon M. Baker, Christopher S. Chen, Robert L. Mauck, Michael T. Yang, Stephen D. Thorpe
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
Mesenchymal stem cell (MSC) differentiation is mediated by soluble and physical cues. In this study, we investigated differentiation-induced transformations in MSC cellular and nuclear biophysical properties and queried their role in mechanosensation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e8d42fc2c008476e3731f4a2dec1f6
https://pubmed.ncbi.nlm.nih.gov/27901466
https://pubmed.ncbi.nlm.nih.gov/27901466
Autor:
Brendon M. Baker, Michael T. Yang, Christopher S. Chen, Ritika Chaturvedi, Sangeeta N. Bhatia, Xiang-Qing Yu, Kelly R. Stevens, Duc-Huy T. Nguyen, Esteban Toro, Peter A. Galie, Alice A. Chen, Jordan S. Miller, Daniel M. Cohen
Publikováno v:
Nature materials
In the absence of perfusable vascular networks, three-dimensional (3D) engineered tissues densely populated with cells quickly develop a necrotic core [1]. Yet the lack of a general approach to rapidly construct such networks remains a major challeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600d3341b485c7bdb12b8a0498e9df78
https://doi.org/10.1038/nmat3357
https://doi.org/10.1038/nmat3357
Autor:
Christopher S. Chen, Yang Kao Wang, Xiang Yu, Daniel M. Cohen, Michael T. Yang, Jeroen Eyckmans, Michele A. Wozniak, Ling-Jie Gao
Publikováno v:
Stem Cells and Development. 21:1176-1186
Osteogenic differentiation of human mesenchymal stem cells (hMSCs) is classically thought to be mediated by different cytokines such as the bone morphogenetic proteins (BMPs). Here, we report that cell adhesion to extracellular matrix (ECM), and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3e0bf9be3c9507429ce7782fede3cc
https://doi.org/10.1089/scd.2011.0293
https://doi.org/10.1089/scd.2011.0293
Autor:
Christopher S. Chen, Brendon G. Ricart, Daniel A. Hammer, Christopher A. Hunter, Michael T. Yang
Publikováno v:
Biophysical Journal. 101(11):2620-2628
Dendritic cells (DCs) migrate from sites of inflammation to secondary lymphoid organs where they initiate the adaptive immune response. Although motility is essential to DC function, the mechanisms by which they migrate are not fully understood. We i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31dc031829527f4e4902ba7a82cc28f5