Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michael T. Petassi"'
Autor:
Alba Guarné, Yao Shen, Michael T. Petassi, Joaquin Ortega, Joseph E. Peters, Josué Gómez-Blanco
Publikováno v:
Nature Structural & Molecular Biology. 29:143-151
Tn7 transposable elements are unique for their highly specific, and sometimes programmable, target-site selection mechanisms and precise insertions. All the elements in the Tn7-family utilize a AAA+ adaptor (TnsC) to coordinates target-site selection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8564a216a4f23be3b76d1d1b0ec3ad
https://doi.org/10.1038/s41594-022-00724-8
https://doi.org/10.1038/s41594-022-00724-8
Autor:
Michael T. Petassi, Amy Tsai, Jung-Un Park, Eshan Mehrotra, Shan-Chi Hsieh, Elizabeth H. Kellogg, Joseph E. Peters, Ailong Ke
Publikováno v:
Science
CRISPR-associated transposition systems allow guide RNA-directed integration of a single DNA cargo in one orientation at a fixed distance from a programmable target sequence. We used cryo-electron microscopy (cryo-EM) to define the mechanism that und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0715213cc1f88ce97e50fdba1766e4
https://doi.org/10.1016/j.bpj.2021.11.1096
https://doi.org/10.1016/j.bpj.2021.11.1096
Publikováno v:
Cell
SummaryCRISPR-Cas defense systems have been coopted multiple times in nature for guide RNA-directed transposition by Tn7-like elements. Prototypic Tn7 uses dedicated proteins for two targeting pathways, one targeting a neutral and conserved attachmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba10923730eab0960f4e9549f00028f
https://doi.org/10.1016/j.cell.2020.11.005
https://doi.org/10.1016/j.cell.2020.11.005
Publikováno v:
Molecular Microbiology.
Horizontally acquired genetic information in bacterial chromosomes accumulates in blocks termed genomic islands. Tn7-like transposons form genomic islands at a programmed insertion site in bacterial chromosomes, attTn7. Transposition involves five tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a12fa9cee56faac794bbdf9b3b298bff
https://doi.org/10.1111/mmi.12740
https://doi.org/10.1111/mmi.12740
Publikováno v:
Molecular microbiology. 93(6)
Horizontally acquired genetic information in bacterial chromosomes accumulates in blocks termed genomic islands. Tn7-like transposons form genomic islands at a programmed insertion site in bacterial chromosomes, attTn7. Transposition involves five tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82354f8752870810c20f110c2a3e87fa
https://pubmed.ncbi.nlm.nih.gov/25091064
https://pubmed.ncbi.nlm.nih.gov/25091064