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Autor:
Yuan-Tsong Chen, Takashi Morita, Hirotoshi Echizen, Michael T. M. Lee, Yosuke Ichimura, Mari Shiomi, Harumi Takahashi, Kiyoshi Mihara
Publikováno v:
Clinical pharmacokinetics. 51(12)
Genetic polymorphisms of cytochrome P450 (CYP) 2C9 (CYP2C9) and vitamin K epoxide reductase complex subunit 1 (VKORC1) and patient demographic characteristics are responsible for inter-individual differences in warfarin maintenance dosage requirement