Recalling gist memory depends on CA1 hippocampal neurons for lifetime retention and CA3 neurons for memory precision

Autor: Erika Atucha, Shih-Pi Ku, Michael T. Lippert, Magdalena M. Sauvage

Publikováno v: Cell Reports, Vol 42, Iss 11, Pp 113317- (2023)

Summary: Why some of us remember events more clearly than others and why memory loses precision over time is a major focus in memory research. Here, we show that the recruitment of specific neuroanatomical pathways within the medial temporal lobe (MT

Externí odkaz: https://doaj.org/article/14a8fb6445e64ec18e5f36b6e0d205b5

Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life

Autor: Gabriel Berdugo-Vega, Gonzalo Arias-Gil, Adrian López-Fernández, Benedetta Artegiani, Joanna M. Wasielewska, Chi-Chieh Lee, Michael T. Lippert, Gerd Kempermann, Kentaroh Takagaki, Federico Calegari

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)

Ageing affects several brain areas causing a decrease in cognitive abilities and memory. We find that increasing the endogenous potential of the hippocampus to generate new neurons throughout life rejuvenates learning and memory, indicating that neur

Externí odkaz: https://doaj.org/article/053faa42850e4fdca82723e9f3346693

CAVE: An Open-Source Tool for Combined Analysis of Head-Mounted Calcium Imaging and Behavior in MATLAB

Autor: Jennifer Tegtmeier, Marcel Brosch, Kathrin Janitzky, Hans-Jochen Heinze, Frank W. Ohl, Michael T. Lippert

Publikováno v: Frontiers in Neuroscience, Vol 12 (2018)

Calcium imaging in freely behaving rodents using head-mounted miniature microscopes is currently becoming an increasingly popular technique in neuroscience. Due to the large amounts of complex data that the technique produces, user friendly software

Externí odkaz: https://doaj.org/article/20cffa7985c048068df425a97fbf2a95

Author Correction: Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life

Autor: Gabriel Berdugo-Vega, Gonzalo Arias-Gil, Adrian López-Fernández, Benedetta Artegiani, Joanna M. Wasielewska, Chi-Chieh Lee, Michael T. Lippert, Gerd Kempermann, Kentaroh Takagaki, Federico Calegari

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Externí odkaz: https://doaj.org/article/8f64781251524094a613455cffc29489

Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life

Autor: Gonzalo Arias-Gil, Gerd Kempermann, Benedetta Artegiani, Joanna M. Wasielewska, Gabriel Berdugo-Vega, Chi-Chieh Lee, Federico Calegari, Kentaroh Takagaki, Michael T. Lippert, Adrian López-Fernández

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications, 11(1):135
Nature Communications 11(1), 135 (2020). doi:10.1038/s41467-019-14026-z

Functional plasticity of the brain decreases during ageing causing marked deficits in contextual learning, allocentric navigation and episodic memory. Adult neurogenesis is a prime example of hippocampal plasticity promoting the contextualisation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f8c45704bcf362ba69e3a7a7ea41de
https://doaj.org/article/053faa42850e4fdca82723e9f3346693