Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Michael T. Ivy"'
Publikováno v:
Oncology letters. 18(6)
Previous phase I DNA-vaccine based clinical trials using Mammaglobin-A (Mam-A), a human breast tumor associated antigen (TAA), demonstrated that this agent was safe and efficient at treating patients with stage IV breast cancer. The long-term success
Autor:
Jens Titze, Michael T. Ivy, Elbert L. Myles, Venkataswarup Tiriveedhi, Jeffrey C. Rathmell, Roy Zent
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1690, p 1690 (2021)
Volume 13
Issue 7
Cancers, Vol 13, Iss 1690, p 1690 (2021)
Volume 13
Issue 7
Simple Summary Cell based immunotherapy is rapidly emerging as a promising cancer treatment. Salt (sodium chloride) treatment to immune cell cultures is known to induce inflammatory activation. In our current study, we analyzed the anti-cancer abilit
Publikováno v:
Cellular Immunology. 302:1-10
Chronic inflammation is known to play a critical role in the development of cancer. Recent evidence suggests that high salt in the tissue microenvironment induces chronic inflammatory milieu. In this report, using three breast cancer-related cell lin
Autor:
Duaa Babaer, Yan Zhao, Jens Titze, Philip E. Lammers, Suneetha Amara, Michael T. Ivy, Venkataswarup Tiriveedhi
Publikováno v:
Oncotarget
Recent evidence from our laboratory has demonstrated that high salt (Δ0.05 M NaCl) induced inflammatory response and cancer cell proliferation through salt inducible kinase-3 (SIK3) upregulation. As calcium influx is known to effect inflammatory res
Autor:
Sri Harsha K. V. Subramanya, Gary Kelley, James Tyus, Ashley Payne, Dafeng Hui, Shannon Byers, Fur-Chi Chen, Samuel N. Nahashon, Xiaofei Wang, Michael T. Ivy, Joseph Donkor, Carl E. Darris, Ann Bohannon-Stewart, Boniface M. Kimathi
Publikováno v:
Genetics Research International
Genetics Research International, Vol 2014 (2014)
Genetics Research International, Vol 2014 (2014)
The identities of genes that underlie population variation in adipose tissue development in farm animals are poorly understood. Previous studies in our laboratory have suggested that increased fat tissue involves the expression modulation of an array
Autor:
Hideki Iwamoto, Jane Wright, Randy D. Blakely, Elizabeth A. Ennis, Shawn M. Ferguson, Ericka C. Holmstrand, C. David Weaver, Katie S. Emerson, Alicia M. Ruggiero, Michael T. Ivy, Michelle Lewis
Publikováno v:
ACS Chemical Neuroscience. 3:767-781
Current therapies to enhance CNS cholinergic function rely primarily on extracellular acetylcholinesterase (AChE) inhibition, a pharmacotherapeutic strategy that produces dose-limiting side effects. The Na(+)-dependent, high-affinity choline transpor
Autor:
Yilun Wang, Michael T. Ivy, Marlo D Kemp, Brenda S. McAdory, James G. Townsel, Zheng Cao, Robert F. Newkirk, Wei Xu
Publikováno v:
Gene. 326:189-199
We describe herein the cloning of a group of syntaxins in Limulus that are associated with the plasma membrane. Initially, multiple degenerate oligonucleotide primers (DOP) and probes were designed from sequences of known plasma membrane associated s
Autor:
Venkataswarup Tiriveedhi, Kevin L. Schey, Sade-Kemi Brown, Babak Banan, Margaret M. Whalen, Suneetha Amara, Michael T. Ivy, Karina Lopez, Elbert L. Myles, Terrance Johnson
The pro-inflammatory cytokines, tumor necrosis factor (TNF)-α, and interleukin (IL)-17, have been implicated in the pathogenesis of liver fibrosis. In this study, we investigated the role of TNFα and IL-17 toward induction of profibrotic factor, pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40020d91628126edf82b602a29905411
https://europepmc.org/articles/PMC4282823/
https://europepmc.org/articles/PMC4282823/
Autor:
Billy G. Hudson, Dorin-Bogdan Borza, W. Hayes McDonald, Aaron L. Fidler, Viravuth P. Yin, Cody L. Stothers, Michael T. Ivy, Robert Steele, Travis A Clark, Sergei V. Chetyrkin, Julie K. Hudson, Aspirnauts, Vadim Pedchenko, Roberto M. Vanacore, Gautam Bhave, Kristie L. Rose
Publikováno v:
Fidler, AL; Vanacore, RM; Chetyrkin, SV; Pedchenko, VK; Bhave, G; Yin, VP; et al.(2014). A unique covalent bond in basement membrane is a primordial innovation for tissue evolution. Proceedings of the National Academy of Sciences of the United States of America, 111(1), 331-336. doi: 10.1073/pnas.1318499111. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/77k6x5zp
Basement membrane, a specialized ECM that underlies polarized epithelium of eumetazoans, provides signaling cues that regulate cell behavior and function in tissue genesis and homeostasis. A collagen IV scaffold, a major component, is essential for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1aea0ec2c3ec2273f399be88f37f35
http://www.escholarship.org/uc/item/77k6x5zp
http://www.escholarship.org/uc/item/77k6x5zp
Publikováno v:
Neuroscience. 102:969-978
Cholinergic neurons have both a low-affinity and a high-affinity choline transport process. The high-affinity choline transport is sodium dependent and thus it can be referred to as choline cotransport. Choline cotransport has been shown to be up-reg