Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Michael T. Falta"'
Autor:
Katherine M Littlefield, Renée O Watson, Jennifer M Schneider, Charles P Neff, Eiko Yamada, Min Zhang, Thomas B Campbell, Michael T Falta, Sarah E Jolley, Andrew P Fontenot, Brent E Palmer
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010359 (2022)
As of January 2022, at least 60 million individuals are estimated to develop post-acute sequelae of SARS-CoV-2 (PASC) after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While elevated levels of SARS-CoV-2-specific T ce
Externí odkaz:
https://doaj.org/article/7e3104f8b8854e44aae8079bdfe996d1
Publikováno v:
J Immunol
Sarcoidosis and chronic beryllium disease are noninfectious lung diseases that are characterized by the presence of noncaseating granulomatous inflammation. Chronic beryllium disease is caused by occupational exposure to beryllium containing particle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da17f141a13478625a98f36e2a775462
https://europepmc.org/articles/PMC9106315/
https://europepmc.org/articles/PMC9106315/
Autor:
Katherine M. Littlefield, Renée O. Watson, Jennifer M. Schneider, Charles P. Neff, Eiko Yamada, Min Zhang, Thomas B. Campbell, Michael T. Falta, Sarah E. Jolley, Andrew P. Fontenot, Brent E. Palmer
As of January 2022, at least 60 million individuals are estimated to develop post-acute sequelae of SARS-CoV-2 (PASC) after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While elevated levels of SARS-CoV-2-specific T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04a4606055be08a434ba461174d87851
https://doi.org/10.1101/2022.02.14.480317
https://doi.org/10.1101/2022.02.14.480317
Autor:
Angela M. Mitchell, Shaodong Dai, Michael T. Falta, Lisa A. Maier, Shaikh M. Atif, Lan Chen, Andrew P. Fontenot, Alex N. Tinega, Sarah A. Greaves, Johan Grunewald, Clemencia Pinilla, Yang Wang, Radleigh Santos, Douglas G. Mack, Avinash Ravindran
Publikováno v:
The Journal of experimental medicine. 218(10)
Löfgren’s syndrome (LS) is an acute form of sarcoidosis characterized by a genetic association with HLA-DRB1*03 (HLA-DR3) and an accumulation of CD4+ T cells of unknown specificity in the bronchoalveolar lavage (BAL). Here, we screened related LS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c193200bacff94a99a0b5792710e2f49
https://pubmed.ncbi.nlm.nih.gov/34515726
https://pubmed.ncbi.nlm.nih.gov/34515726
Autor:
Alex N. Tinega, Allison K. Martin, John W. Kappler, Douglas G. Mack, Lisa A. Maier, Michael T. Falta, Clemencia Pinilla, Frances Crawford, Jeremy Chase Crawford, Li Li, Paul G. Thomas, Shaikh M. Atif, Radleigh Santos, Laurie G. Landry, Maki Nakayama, Andrew P. Fontenot
Publikováno v:
J Clin Invest
Discovering dominant epitopes for T cells, particularly CD4+ T cells, in human immune-mediated diseases remains a significant challenge. Here, we used bronchoalveolar lavage (BAL) cells from HLA-DP2-expressing patients with chronic beryllium disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfdd75031b04936ec9af30746ce26ea
https://pubmed.ncbi.nlm.nih.gov/33938450
https://pubmed.ncbi.nlm.nih.gov/33938450
Autor:
Grecia Jimenez, Sonia M. Leach, Jill E. Slansky, Peter P. Lee, Tullia C. Bruno, Paul R. Reynolds, Paul T. Spellman, Daniel J. Munson, John H. Yim, Kami E. Chiotti, Diana L. Simons, Michael T. Falta, Taizo A. Nakano, Zuly E. Parra, Dmitri V. Rozanov, Colt Egelston, Andrew P. Fontenot, Virginia F. Borges, Brandon Moore, John W. Kappler
Publikováno v:
Proceedings of the National Academy of Sciences. 113:8272-8277
Infiltration of T cells in breast tumors correlates with improved survival of patients with breast cancer, despite relatively few mutations in these tumors. To determine if T-cell specificity can be harnessed to augment immunotherapies of breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a594cedf315fb6d64255c7097e5c8b9
https://doi.org/10.1073/pnas.1606994113
https://doi.org/10.1073/pnas.1606994113
Publikováno v:
The Journal of Immunology. 196:22-27
Chronic beryllium (Be) disease is a granulomatous lung disorder that results from Be exposure in a genetically susceptible host. The disease is characterized by the accumulation of Be-responsive CD4+ T cells in the lung, and genetic susceptibility is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c327486d5133e6f299316e8ad9dbf7f2
https://doi.org/10.4049/jimmunol.1502011
https://doi.org/10.4049/jimmunol.1502011
Autor:
Frances Crawford, Douglas G. Mack, John W. Kappler, Terry Gordon, Allison K. Martin, Philip L. Simonian, Andrew P. Fontenot, Robert R. Mercer, Rubin M. Tuder, Amy S. McKee, Michael T. Falta, Mark D. Hoover, Philippa Marrack
Publikováno v:
Proceedings of the National Academy of Sciences. 111:8553-8558
Susceptibility to chronic beryllium disease (CBD) is linked to certain HLA-DP molecules, including HLA-DP2. To elucidate the molecular basis of this association, we exposed mice transgenic (Tg) for HLA-DP2 to beryllium oxide (BeO) via oropharyngeal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0351477d8ebf5691f3a0be2bd754a0ef
https://doi.org/10.1073/pnas.1408048111
https://doi.org/10.1073/pnas.1408048111
Autor:
Andrew K. Sullivan, Douglas G. Mack, Manoel Otávio da Costa Rocha, Andrew P. Fontenot, Walderez O. Dutra, Michael T. Falta, Brian M. Freed, Kenneth John Gollob, Cristiane Alves da Silva Menezes
Publikováno v:
Clinical and Experimental Immunology. 169:109-118
Summary Human infection with Trypanosoma cruzi leads to Chagas disease, which presents as several different clinical conditions ranging from an asymptomatic form to a severe dilated cardiomyopathy. Several studies have demonstrated that T cells play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a6c681195d17c168a60094fc0f8762
https://doi.org/10.1111/j.1365-2249.2012.04608.x
https://doi.org/10.1111/j.1365-2249.2012.04608.x
Publikováno v:
The Journal of Immunology. 187:3694-3703
Unconventional antigens, such as metals, stimulate T cells in a very specific manner. To delineate the binding landscape for metal-specific T cell recognition, alanine screens were performed on a set of beryllium (Be)-specific T cell receptors (TCR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9227e3abbc7bdfc965b9befe5459e200
https://doi.org/10.4049/jimmunol.1101872
https://doi.org/10.4049/jimmunol.1101872