Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michael T. Empl"'
Autor:
Pascal Hoffmann, Marion Burmester, Marion Langeheine, Ralph Brehm, Michael T Empl, Bettina Seeger, Gerhard Breves
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0257824 (2021)
Infectious gastrointestinal diseases are frequently caused by toxins secreted by pathogens which may impair physiological functions of the intestines, for instance by cholera toxin or by heat-labile enterotoxin. To obtain a functional model of the hu
Externí odkaz:
https://doaj.org/article/45c0730f55d248448ba5588d540ad1cf
Autor:
Nadja Kampschulte, Michael T. Empl, Nils Helge Schebb, Ayah Alasmer, Michael Krohn, Pablo Steinberg
Publikováno v:
Journal of Agricultural and Food Chemistry. 68:9235-9244
The products of the cytochrome P450 monooxygenase (CYP)-catalyzed oxidation of arachidonic acid (AA), that is, epoxy- and hydroxy-fatty acids, play a crucial role in the homeostasis of several physiological processes. In a liver microsome-based multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64969f8c2173c9fc3dce3abcf654dbf8
https://doi.org/10.1021/acs.jafc.0c04690
https://doi.org/10.1021/acs.jafc.0c04690
Autor:
Christophe Lacroix, Michael T. Empl, Jianbo Zhang, Mostafa I. Fekry, Christina Engels, Shana J. Sturla, Clarissa Schwab, Mirjam Schneider, Pablo Steinberg
Publikováno v:
Toxicological Sciences
Toxicological Sciences, 159 (1)
Toxicological Sciences, 159 (1)
The diverse community of microbes present in the human gut has emerged as an important factor for cancer risk, potentially by altering exposure to chemical carcinogens. In the present study, human gut bacteria were tested for their capacity to transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc81fbabc11d86eab714d50d526678b9
http://doc.rero.ch/record/333134/files/TOXSCI_159_1_266.pdf
http://doc.rero.ch/record/333134/files/TOXSCI_159_1_266.pdf
Autor:
Ya-Qi Zhang, Marianna Lykaki, Jorg Thöming, Stefan Stolte, Michael T. Empl, Pablo Steinberg, Marta Markiewicz
Publikováno v:
Energy & Environmental Science. 12:366-383
Due to the finite nature and scarcity of crude oil-based fuels, increasing attention is being directed towards various forms of renewable energy. To obtain a fully functional renewable energy system, some compensation for the spatiotemporal fluctuati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9283bb815f74a60e6d72f92d69038a64
https://doi.org/10.1039/c8ee01696h
https://doi.org/10.1039/c8ee01696h
Autor:
Pascal Hoffmann, Susanne M Geisen, Nina Seiwert, Markus Christmann, Jerry W. Shay, Tina Kostka, Pablo Steinberg, Michael T. Empl, Jörg Fahrer, Janine Adam, Bettina Seeger, Shana J. Sturla
Publikováno v:
Carcinogenesis, 42 (8)
The protein O6-methylguanine-DNA methyltransferase (MGMT) is able to repair the mutagenic O6-methylguanine (O6-MeG) adduct back to guanine. In this context, it may protect against colorectal cancer formation associated with N-nitroso compounds. Such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d59ccbdd6fe940c9776ddd7b0f03a2
https://pubmed.ncbi.nlm.nih.gov/34115837
https://pubmed.ncbi.nlm.nih.gov/34115837
Autor:
Jörg Fohrer, Jörg Fahrer, Karlis Briviba, Pablo Steinberg, Michael T. Empl, Tina Kostka, Claudia Guigas, Nina Seiwert
Publikováno v:
Archives of Toxicology
Data from epidemiological studies suggest that consumption of red and processed meat is a factor contributing to colorectal carcinogenesis. Red meat contains high amounts of heme, which in turn can be converted to its nitrosylated form, NO-heme, when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c14728fb263f331149171f228b67415
https://pubmed.ncbi.nlm.nih.gov/32671443
https://pubmed.ncbi.nlm.nih.gov/32671443
Publikováno v:
Food and Chemical Toxicology. 95:196-202
High consumption of red meat entails a higher risk of developing colorectal cancer. Methionine, which is more frequently a component of animal proteins, and folic acid are members of the one carbon cycle and as such important players in DNA methylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30221dfe4d1a0f604680ebec63a35376
https://doi.org/10.1016/j.fct.2016.07.014
https://doi.org/10.1016/j.fct.2016.07.014
Autor:
Ina Willenberg, Anne Büsing, Pablo Steinberg, Astrid M. Drotleff, Waldemar Ternes, Michael T. Empl
Publikováno v:
Journal of Agricultural and Food Chemistry. 63:8930-8939
Tocotrienols, a vitamin E subgroup, exert potent anticancer effects, but easily degrade due to oxidation. Eight vitamin E reference compounds, α-, β-, γ-, or δ-tocopherols or -tocotrienols, were thermally oxidized in n-hexane. The corresponding p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282e5d59e95b4c11252c81d0e09fda08
https://doi.org/10.1021/acs.jafc.5b04388
https://doi.org/10.1021/acs.jafc.5b04388
Publikováno v:
Phytotherapy Research. 29:1640-1645
Polyphenols are secondary plant metabolites that possess potentially health-promoting properties and which occur in various edible plants and plant products. Especially the stilbenoid resveratrol has been extensively studied regarding its anticarcino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50386afdaf6f4c34525ad2b6ebd18195
https://doi.org/10.1002/ptr.5443
https://doi.org/10.1002/ptr.5443
Autor:
Laura C. Bartel, Maria Michael, Ina Willenberg, Jasmin Wonik, Nils Helge Schebb, Michael T. Empl
Publikováno v:
Food Chemistry. 167:245-250
Resveratrol oligomers are biologically active polyphenols found in wine. No information about the bioavailability of these polyphenols is available. In order to discover if the resveratrol oligomers can pass the intestinal barrier, transport of the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d8f4cbb50136e09c0d101b5f72d7ed
https://doi.org/10.1016/j.foodchem.2014.06.103
https://doi.org/10.1016/j.foodchem.2014.06.103