Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Michael T. Boyne"'
Autor:
William J. Kelley, Kathleen M. Wragg, Judy Chen, Tushar Murthy, Qichen Xu, Michael T. Boyne, Joseph R. Podojil, Adam Elhofy, Daniel R. Goldstein
Publikováno v:
JCI Insight, Vol 7, Iss 15 (2022)
Older people exhibit dysregulated innate immunity to respiratory viral infections, including influenza and SARS-CoV-2, and show an increase in morbidity and mortality. Nanoparticles are a potential practical therapeutic that could reduce exaggerated
Externí odkaz:
https://doaj.org/article/4576ad08e65547c38dee32f1176ea356
Autor:
Joseph R. Podojil, Andrew C. Cogswell, Ming-Yi Chiang, Valerie Eaton, Igal Ifergan, Tobias Neef, Dan Xu, Khyati A. Meghani, Yanni Yu, Sophia M. Orbach, Tushar Murthy, Michael T. Boyne, Adam Elhofy, Lonnie D. Shea, Joshua J. Meeks, Stephen D. Miller
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cancer treatment utilizing infusion therapies to enhance the patient’s own immune response against the tumor have shown significant functionality in a small subpopulation of patients. Additionally, advances have been made in the utilization of nano
Externí odkaz:
https://doaj.org/article/ab783c6c26c045b0aab255a9140c3f66
Autor:
Joseph R. Podojil, Samantha Genardi, Ming-Yi Chiang, Sandeep Kakade, Tobias Neef, Tushar Murthy, Michael T. Boyne, Adam Elhofy, Stephen D. Miller
Publikováno v:
The Journal of Immunology. 209:465-475
Type 1 diabetes (T1D) is an autoimmune disease characterized by T and B cell responses to proteins expressed by insulin-producing pancreatic β cells, inflammatory lesions within islets (insulitis), and β cell loss. We previously showed that Ag-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223dff27019c8dec48e0db098ab780b5
https://doi.org/10.4049/jimmunol.2200208
https://doi.org/10.4049/jimmunol.2200208
Autor:
Laxminarasimha, Donthireddy, Prashanthi, Vonteddu, Tushar, Murthy, Taekyoung, Kwak, Rukiye-Nazan, Eraslan, Joseph R, Podojil, Adam, Elhofy, Michael T, Boyne, John J, Puisis, Filippo, Veglia, Surya S, Singh, Farokh, Dotiwala, Luis J, Montaner, Dmitry I, Gabrilovich
Publikováno v:
Journal of Cancer. 13:1933-1944
In this study, we evaluated the ability of negatively charged bio-degradable nanoparticles, ONP- 302, to inhibit tumor growth. Therapeutic treatment with ONP-302 in vivo resulted in a marked delay in tumor growth in three different syngeneic tumor mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c562ef1ef7d67bf1502c76f2830cae
https://doi.org/10.7150/jca.69338
https://doi.org/10.7150/jca.69338
Publikováno v:
In Journal of Pharmaceutical and Biomedical Analysis August-September 2012 67-68:42-50
Autor:
William J. Kelley, Kathleen M. Wragg, Judy Chen, Tushar Murthy, Qichen Xu, Michael T. Boyne, Joseph R. Podojil, Adam Elhofy, Daniel R. Goldstein
Publikováno v:
JCI insight. 7(15)
Older people exhibit dysregulated innate immunity to respiratory viral infections, including influenza and SARS-CoV-2, and show an increase in morbidity and mortality. Nanoparticles are a potential practical therapeutic that could reduce exaggerated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5c5a358cdc5959902af077ca4e2324
https://pubmed.ncbi.nlm.nih.gov/35737459
https://pubmed.ncbi.nlm.nih.gov/35737459
Autor:
Michael T. Boyne, Anneliese Faustino, John E. Schiel, Eric Pang, Deepali Rathore, Sarah Rogstad
Publikováno v:
Expert Review of Proteomics. 15:431-449
Mass spectrometry (MS) is widely used in the characterization of biomolecules including peptide and protein therapeutics. These biotechnology products have seen rapid growth over the past few decades and continue to dominate the global pharmaceutical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dab3e0b432c0ec998f4a1f4665e1e812
https://doi.org/10.1080/14789450.2018.1469982
https://doi.org/10.1080/14789450.2018.1469982
Autor:
Tobias L. Freitag, Joseph A. Murray, Michael T. Boyne, Michael Koren, Stephen D. Miller, Daniel A. Leffler, Daniel R. Getts, Mark Matson, Thomas H. Oliphant, Amy Morris, Adam C. Bledsoe, Jocelyn A. Silvester, Seppo Meri, Glennda Smithson, Michele Gerber, Robert Fogel, Ciaran P. Kelly, Paul K. Haynes, Adam Elhofy, M. Roy First, Mark Turner, Tsung Teh Wu, Barbara E. Rizzardi, Joseph R. Podojil
Publikováno v:
Gastroenterology
BACKGROUND & AIMS: In celiac disease (CeD), gluten induces immune activation, leading to enteropathy. TAK-101, gluten protein (gliadin) encapsulated in negatively charged poly(dl-lactide-co-glycolic acid) nanoparticles, is designed to induce gluten-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc2a7e97e39bc121b3a980a6b51b15f
https://doi.org/10.1053/j.gastro.2021.03.014
https://doi.org/10.1053/j.gastro.2021.03.014
The suitability of a liquid chromatography–high-resolution mass spectrometry (LC–HRMS) method for monitoring peptide drug product quality is demonstrated on three case studies using the peptide drugs salmon calcitonin, bivalirudin and exenatide a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a71486c98a654a55e8dfc8aea072637
https://doi.org/10.1039/9781788016445-00313
https://doi.org/10.1039/9781788016445-00313
Publikováno v:
The Science and Regulations of Naturally Derived Complex Drugs ISBN: 9783030117504
Mass spectrometry is an essential tool for the characterization of complex drug products. Characterization of complex drug products presents unique challenges, as these products are often difficult to characterize not only because of the complexity i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfa39a1cd08e05c72f69c5ebf90701f9
https://doi.org/10.1007/978-3-030-11751-1_8
https://doi.org/10.1007/978-3-030-11751-1_8